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Alzheimer’s Disease- Curcumin, Resveratrol

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In addition to mounting research on herbal compounds for the treatment of Alzheimer’s Disease, curcuminoids and resveratrol appear to be beneficial as anti-Alzheimer’s Disease agents.

What does it mean when two natural compounds are both effective therapies for two seemingly distinct diseases?Curcumin and Optimized Resveratrol are both effective in killing multiple myeloma, my cancer. The study linked and excerpted below talk about curcumin and Optimized Resveratrol ‘s ability to also treat Alzheimer’s Disease (AD).

And these two chronic, incurable diseases are not the only diseases that Curcumin and Optimized Resveratrol treat.

  • Curcumin as nutritional supplement may help treat cancer, inflammation, ulcerative colitis, rheumatoid arthritis, osteo arthritis, diabetes, depression, anxiety, cognitive function and fatigue, chronic anterior uveitis and other conditions.”
  • “Resveratrol  supplementation may treat cancer, may lower bad cholesterol, may reduce levels of inflammation,  improves insulin sensitivity in diabetics, may help memory function and may help prevent the onset of Alzheimer’s Disease dementia and other neurodegenerative disorders.”

Full disclosure. shortly after my high-dose toxic cancer therapies in 1994 and 1995, I developed a common side effect called chemotherapy-induced cognitive dysfunction, also called chemo brain.

I discovered a host of evidence-brain health therapies such as curcumin and resveratrol that have helped my health my brain damage.

I hope that enhancing my brain health prevents all types of demential including Alzheimer’s Disease.

I am a long-term survivor of an incurable cancer and cancer coach. For more information about natural supplementation to treat Alzheimer’s Disease, scroll down the page, post a question or comment and I will reply ASAP.

Thank you,

David Emerson

  • Cancer Survivor
  • Cancer Coach
  • Director PeopleBeatingCancer

Recommended Reading:


Curcuminoids and resveratrol as anti-Alzheimer agents.

“Alzheimer’s disease (AD) is by far the most common cause of dementia globally. This neurodegenerative disorder of the brain is chronic and progressive, characterized clinically by the deterioration in the key symptoms of behavioral and cognitive abilities

Treatment options for this disease currently are limited…

In addition to mounting research on herbal compounds for the treatment of AD, curcuminoids and resveratrol appear to be beneficial as anti-Alzheimer’s Disease agents…

This review article revisits and presents the current research done on the potential of the curcuminoids curcumin and demethoxycurcumin and the polyphenolic compound resveratrol as anti-AD compounds.”


Curcumin- Non-Toxic, Inexpensive, Alzheimer’s Disease Therapy

There is limited choice in modern Alzheimer’s Disease therapeutics, and drugs available have limited success with multiple side effects in addition to high cost

There are distinct similarities between my cancer, multiple myeloma and Alzheimer’s Disease. Both are incurable. Both have few effective conventional treatments. What conventional therapies there are cause harmful side effects and are expensive. Curcumin supplementation is a nutriceutical that is effective for both myeloma and AD, causes little collateral damage and is inexpensive.

So why don’t oncologists and neurologists prescribe Curcumin to their patients??? Why hasn’t the Food and Drug Administration approved Curcumin for Multiple Myeloma and Alzheimer’s Disease? My guess is that pharmaceutical companies won’t pay for studies for products that can’t be patented.

The brand of Curcumin that I take is Life Extension Super Bio Curcumin . This formulation has shown the ability to absorb into the blood stream better than other brands. I recommend LE Super Bio Curcumin .

For more information about nutritional supplementation and chronic disease, scroll down the page, post a question or a comment and I will reply ASAP.

Therapeutic potential of turmeric in Alzheimer’s disease: curcumin or curcuminoids?

“Alzheimer’s disease (AD) is the most common form of dementia. There is limited choice in modern therapeutics, and drugs available have limited success with multiple side effects in addition to high cost

Hence, newer and alternate treatment options are being explored for effective and safer therapeutic targets to address AD…

Turmeric possesses multiple medicinal uses including treatment for AD. Curcuminoids, a mixture of CU, demethoxycurcumin, and bisdemethoxycurcumin, are vital constituents of turmeric.

The progress in understanding the disease etiology demands a multiple-site-targeted therapy, and the curcuminoid mixture of all components, each with different merits, makes this mixture more promising in combating the challenging disease.”


The Most BioAvailable Curcumin Formulas

“Based on a review of these studies, it is evident that better bioavailability of formulated curcumin (CU) products is mostly attributed to improved solubility, stability, and possibly low first-pass metabolism”

A search of the Pubmed database for the word curcumin yields 601 studies spanning health topics from multiple myeloma (MM) and colorectal cancer, to chemotherapy regimens that integrate with CU, to Alzheimer’s Disease, arthritis and more. Based on years of reading studies and personal accounts, I think it is safe to say that CU supplementation is safe and relatively inexpensive and effective.

I have read posts about myeloma patients taking daily doses of CU from 400 milligrams to 8 grams (1000 milligrams = 1 gram). By almost any measure, CU is a safe, inexpensive wonder drug.

The only challenge is that CU is famously difficult to absorb in the body. In other words, a person has to mix curcumin with some sort of fat (coconut oil, chocolate, etc.) or take a brand of curcumin capsule that is already formulated to be more “bioavailable” in order to derive the full benefit of CU.

The study linked and exerpted below reviews different formulations of CU. The study itself lists the three most bioavailable formulation/brand of CU and I’ve added an excerpt from a further review from Consumerlab.com that lists four additional bioavailable brands of CU.

I consult the independent evaluation service Consumerlab.com frequently. For one low annual payment, I can read about and evaluate all of the nutritional supplements that I take.

Please watch the video below to learn more about the evidence-based, integrative therapies to combat treatment side effects and enhance your chemotherapy.

The challenge for every myeloma patient is to achieve the deepest, longest remission possible while sustaining the least amount of collateral damage (side effects) possible. Numerous studies document the anti-MM and integrative efficacy of curcumin.

This link is to the Google search page for “curcumin in myeloma.” Whether it is an article authored by Pat Killingsworth or Margaret from Margaret’s Corner, or PubMed, curcumin is documented to be both cytotoxic to myeloma in addition to being “integrative”  or enhancing the action of Velcade, Revlimid, and Thalidomide.

A common question asked by multiple myeloma patients considering supplementing with curcumin is about the daily dose. Unfortunately, I have several possible answers:

  • The research into MM and curcumin usually refers to a “time and dose dependent manner.” Meaning, the more curcumin the patient takes, the more MM cells are killed.
  • I read about patients with active MM taking doses at many different amounts, from 1 gram a day up to 8 grams a day.
  • For comparison, I take 400 milligrams. My MM is not active therefore I take a maintenance dose. To clarify, 1000 milligrams = 1 gram.

David Emerson

  • Myeloma Survivor
  • MM Cancer Coach
  • Director PeopleBeatingCancer

Recommended Reading:


Curcumin

CU is a bright yellow chemical produced by some plants. It is the principal curcuminoid of turmeric (Curcuma longa), a member of the ginger family, Zingiberaceae. It is sold as an herbal supplement, cosmetics ingredient, food flavoring, and food coloring.[1]

Turmeric curcumin benefits

“Are you looking for a way to boost every facet of your health with a single spice? It sounds crazy, but turmeric curcumin with BioPerine may be the magic supplement we’ve been seeking. Turmeric benefits the body and mind in more ways than you can imagine. Similar to bone broth, turmeric impacts almost every facet of life. Over 10,000 peer-reviewed and clinical studies support using turmeric for better health…”

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5 comments
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