Aronja has chemotherapeutic properties against acute lymphoblastic leukemia (ALL)… Red Wine Polyphenols induce apoptosis in human lymphoblastic leukemia cells
My life as a long-term cancer survivor of an “incurable cancer” can be characterized as evidence-based but non-conventional. Further, I am therapy-agnostic meaning I don’t care if a therapy is conventional, or non-conventional. I just care what works and doesn’t cause collateral damage aka side effects.
I supplement with Life Extension Optimized Resveratrol. Resveratrol is the “red wine polyphenols” discussed in the study linked below.
Nutritional supplementation isn’t about taking one-a-day or centrum synthetic multivitamins. I believe that supplementation is about putting red wine polyphenols, for example, in your body regularly (without drinking a bunch of wine…).
An alternative cancer therapy put me in complete remission in early 1999, I worried of either a relapse of my primary cancer, multiple myeloma or a secondary cancer from all the toxic therapies that I had undergone from ’95-’97.
The risk of a relapse or being diagnosed with a secondary cancer since my complete remission in ’99 is well over 100% by now. I remain cancer-free through nutrition, nutritional supplementation, daily moderate exercise and an anti-cancer lifestyle.
I am both a cancer survivor and cancer coach. Over 14 years of experience and research coupled with my interaction with cancer patients, survivors and caregivers has taught me that there are a host of non-conventional cancer therapies than can be of real value to blood cancer patients.
Have you been diagnosed with leukemia? If so, what stage?
For more information about non-conventional cancer therapies scroll down the page, post a question or comment and I will reply ASAP.
“Aronia melanocarpa (black chokeberry) has attracted scientific interest due to its deep purple, almost black pigmentation that arises from dense contents of polyphenols, especially anthocyanins.”
“The aim of the present study was to determine the anticancer effect of a polyphenol-rich Aronia melanocarpa juice (AMJ) containing 7.15 g/L of polyphenols in the acute lymphoblastic leukemia Jurkat cell line, and, if so, to clarify the underlying mechanism and to identify the active polyphenols involved. AMJ inhibited cell proliferation, which was associated with cell cycle arrest in G(2)/M phase, and caused the induction of apoptosis…
In addition, AMJ exerted a strong pro-apoptotic effect in human primary lymphoblastic leukemia cells but not in human normal primary T-lymphocytes. Thus, the present findings indicate that AMJ exhibits strong anticancer activity through a redox-sensitive mechanism in the p53-deficient Jurkat cells and that this effect involves several types of polyphenols. They further suggest that AMJ has chemotherapeutic properties against acute lymphoblastic leukemia by selectively targeting lymphoblast-derived tumor cells.”
“This large group of natural phenols can be broadly separated into two categories, flavonoids and non-flavonoids. Flavonoids include the anthocyanins and tannins which contribute to the color and mouthfeel of the wine. The non-flavonoids include the stilbenoids such as resveratrol and phenolic acids such as benzoic, caffeic and cinnamic acids…”
“The aim of the present study was to determine whether a red wine polyphenolic extract (RWPs, a rich source of polyphenols; 2.9g/L) affects the proliferation of human lymphoblastic leukemia cells (Jurkat cells)…
Thus, these findings indicate that Red Wine Polyphenols induce apoptosis in Jurkat cells by a redox-sensitive mechanism involving the intracellular formation of superoxide anions and consequently the up-regulation of p73 and down-regulation of UHRF1…”