Ask the Cancer Coach-“Metastatic prostate cancer, gleason score of 9”

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Cancer Coach- I have prostate cancer gleason 9 that has spread to bones- my situation is as follows:

My History

1. I was diagnosed with Gleason 9 Prostate Cancer in September 2011 with PSA of 53
2. Prostate in Lymph nodes at that time.
3. October started Hormon Therapy and casadox 0.50MG
4. December 2011 started radiation (35 Sessions ) ended in January 2012
5. February 2012 PSA 1.53
6. May 2012 PSA 3.54
7. May 2012 CT SCAN and Bone Scan ( Cancer already in rib Bone )
7. December 2012 PSA 3.9
8. May 2013 PSA 9.8
9. I am still on Hormon therapy ( Zoladox and 150MG of Casodex )
10. PSA is still around 8 till now
11, I am 56 Years old
12. My health is excellant, I work 10 hours aday and walk several KM a day.
13. From your Experience, can this type of cancer be managed especially it is in the bones?
14. How long peaople live like in my case
15. I live in JOrdan
Your views please

George


Hi George-

I will address each of your items below-

1. “I was diagnosed with Gleason 9 Prostate Cancer in September 2011 with PSA of 53”

You are coming up on your two year anniversary of what seems to me to be advanced prostate cancer- you are doing well based on this.

2. “Prostate in Lymph nodes at that time”

Lymph node involvement adds to your PCa complications-

3. October started Hormone Therapy and casadox 0.50MG
4. December 2011 started radiation (35 Sessions ) ended in January 2012
5. February 2012 PSA 1.53
6. May 2012 PSA 3.54
7. May 2012 CT SCAN and Bone Scan ( Cancer already in rib Bone )
7. December 2012 PSA 3.9
8. May 2013 PSA 9.8
9. I am still on Hormone therapy ( Zoladox and 150MG of Casodex )
10. PSA is still around 8 till now

Your radiation and chemo has managed to reduce your PSA levels- this is good.

11, I am 56 Years old
12. My health is excellant, I work 10 hours a day and walk several KM a day.

I think it is to your credit that you are working long days and walking several KM a day. The walking has the effect of strengthening bones.

13. From your Experience, can this type of cancer be managed especially it is in the bones?

Based on what I have read and researched about prostate cancer, you can integrate your conventional therapy with adjuvant or lifestyle changes. In other words, nutritional supplementation such as curcumin, green tea, vitamin D3, ellagic acid,  others, has been shown to increase the efficacy of chemo while reducing toxicity. I will link studies below.

Green Tea, Curcumin, Fish oil, Vit. D, Pomi-T food supplement Inhibit Prostate Cancer Tumor Growth, Research Finds

“My great-grandfather and grandfather both died with prostate cancer and both my uncle and father are living with prostate cancer. I have to believe that chances are good that I will develop prostate cancer someday. And I certainly keep a close watch on my PSA levels…”

Intensive lifestyle changes may affect the progression of prostate cancer.

“None of the experimental group patients but 6 control patients underwent conventional treatment due to an increase in PSA and/or progression of disease on magnetic resonance imaging. PSA decreased 4% in the experimental group but increased 6% in the control group (p = 0.016)…”

Please keep in mind that your lifestyle CAN change your genetic expression in regards to your prostate cancer-

I am a long-term survivor of an “incurable” cancer. I don’t believe any cancer at any stage is incurable. Yes, your situation is difficult but no situation is hopeless.

Let me know if you have any questions.

David Emerson

  • Cancer Survivor
  • Cancer Coach
  • Director PeopleBeatingCancer

The Most BioAvailable Curcumin Formulas

“Based on a review of these studies, it is evident that better bioavailability of formulated curcumin (CU) products is mostly attributed to improved solubility, stability, and possibly low first-pass metabolism”

A search of the Pubmed database for the word curcumin yields 601 studies spaning health topics from multiple myeloma and colorectal cancer, to chemotherapies that synergizes with CU, to Alzheimer’s Disease, arthritis and more. Based on years of reading studies and personal accounts, I think it is safe to say that CU supplementation is safe and relatively inexpensive.

I have read about myeloma patients taking daily doses of CU from 400 milligrams to 8 grams (1000 milligrams = 1 gram). By almost any measure, CU is a safe, inexpensive wonder drug.

The only challenge is that CU is famously difficult to absorb in the body. In other words, a person has to mix curcumin with some sort of fat (coconut oil, chocolate, etc.) or take a brand of curcumin capsule that is already formulated to be more “bioavailable” in order to derive the full benefit of CU.

The study linked and exerpted below reviews different formulations of CU. The study itself lists the three most bioavailable formulation/brand of CU and I’ve added an excerpt from a further review from Consumerlab.com that lists four additional bioavailable brands of CU.


Recommended Reading:


Curcumin

CU is a bright yellow chemical produced by some plants. It is the principal curcuminoid of turmeric (Curcuma longa), a member of the ginger family, Zingiberaceae. It is sold as an herbal supplement, cosmetics ingredient, food flavoring, and food coloring.[1]

Bioavailable curcumin formulations: A review of pharmacokinetic studies in healthy volunteers.

“Curcumin is a widely studied natural compound which has shown tremendous in vitro therapeutic potential. Despite that, the clinical efficacy of the native CU is weak due to its low bioavailability and high metabolism in the gastrointestinal tract. During the last decade, researchers have come up with different formulations with a focus on improving the bioavailability of curcumin. As a result, a significant number of bioavailable curcumin-based formulations were introduced with the varying range of enhanced bioavailability.

The purpose of this review is to collate the published clinical studies of CU products with improved bioavailability over conventional (unformulated) CU. Based on the literature search, 11 curcumin formulations with available human bioavailability and pharmacokinetics data were included in this review. Further, the data on clinical study design, analytical method, pharmacokinetic parameters and other relevant details of each formulation were extracted.

Based on a review of these studies, it is evident that better bioavailability of formulated curcumin products is mostly attributed to improved solubility, stability, and possibly low first-pass metabolism. The review hopes to provide a quick reference guide for anyone looking information on these bioavailable curcumin formulations.

Based on the published reports,

exhibited over 100-fold higher bioavailability relative to reference unformulated CU. Suggested mechanisms accounting for improved bioavailability of the formulations and details on the bioanalysis methods are also discussed.”

According to Consumerlab.com:

“Novasol has the highest bioavailability (185 x compared to unforumulated CU), followed by Curcuwin (136 x), Longvida (100 x), Meriva (48 x), BCM-95 (27 x), Curcumin C3 Complex + Bioperene (20 x), and then Theracumin (16 x).”

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