Learn how you can manage and alleviate your current side effects while actively working to prevent a relapse or secondary cancer using evidence-based, non-toxic therapies.
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Adolescent and Young Adult (AYA) cancer survivors as well as survivors of pediatric cancers can be considered to be cured of their cancer yet experience a myriad of long-tern and late stage side effects in the years and decades following the end of conventional therapies.
I should know. I am an AYA cancer survivor who has lived with long-term and late stage side effects since the completion of my autologous stem cell transplant in late 1995. Though I gave been “cancer free” since 1999.
Full disclosure: I was 34 when I was first diagnosed. This is pretty old for a pediatric or AYA cancer patient. My point in researching and writing this post is two things.
Let me be specific.
I will focus on the studies linked and excerpted below.
The bottom study below documents the depressive feelings caused by the survivor coming to the realization that he/she will be dogged by long-term and late stage side effects for the rest of their lives.
Again, the issues is conventional FDA approved thinking versus evidence-based but non-conventional thinking and therapies. This approach is highlighted in the posts below.
If you would like to learn more about side effect prevention, scroll down the page, post a question or a comment and I will reply to you ASAP.
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Hang in there.
“Children with Hodgkin lymphoma can be cured with intensive chemotherapy, radiation, and other modalities, but a large majority of patients who survive into adulthood may pay a steep price years later in terms of accelerated aging and neurocognitive impairment…
In addition, this accelerated epigenetic aging in HL survivors was accompanied by neurocognitive deficits, including declines in visual-motor processing, short-term memory, verbal learning and recall, and executive function…
Williams and colleagues had previously reported that compared with their healthy siblings, long-term survivors of HL had significantly higher risk (P < .05 for all comparisons) of neurocognitive impairment, anxiety, depression, unemployment, and impaired physical/mental quality of life…
More than 80% of the survivors had some degree of accelerated aging, compared with only 23% of controls…”
A Toxic Inheritance: Chemotherapy Could Increase Disease Susptibiity in Future Generations
“New research led by Washington State University has found that a common chemotherapy drug called ifosfamide may have toxic effects that can be passed down to the children and grandchildren of adolescent cancer survivors…
The study, published in the journal iScience, discovered that male rats who received ifosfamide during adolescence had an increased incidence of disease in their offspring and grand-offspring. This is the first known study to show that the susceptibility to disease resulting from cancer treatment can be passed down to the third generation of unexposed offspring…
The findings suggest that if a patient receives chemotherapy, and then later has children, that their grandchildren, and even great-grandchildren, may have an increased disease susceptibility due to their ancestors’ chemotherapy exposure,” said Michael Skinner, a WSU biologist and corresponding author on the study…
The researchers also analyzed the rats’ epigenomes, which are molecular processes that are independent of DNA sequence, but influence gene expression, including turning genes on or off. Previous research has shown that exposure to toxicants, particularly during development, can create epigenetic changes that can be passed down through sperm and ova…
The results of the researchers’ analysis showed epigenetic changes in two generations linked to the chemotherapy exposure of the originally exposed rats. The fact that these changes could be seen in the grand-offspring, who had no direct exposure to the chemotherapy drug, indicates that the negative effects were passed down through epigenetic inheritance…”