Recently Diagnosed or Relapsed? Stop Looking For a Miracle Cure, and Use Evidence-Based Therapies To Enhance Your Treatment and Prolong Your Remission
Multiple Myeloma an incurable disease, but I have spent the last 25 years in remission using a blend of conventional oncology and evidence-based nutrition, supplementation, and lifestyle therapies from peer-reviewed studies that your oncologist probably hasn't told you about.
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Can Myeloma Patients Slow Aging?
Can myeloma patients slow aging? Chemotherapy causes senescence, therefore ageing myeloma patients. The more chemotherapy the MM patient undergoes, the more their bodies age.
This post is not about looking younger. This post is about MM patients trying to counteract some of the negative effects of chemotherapy. Senescent cells can make MM more aggressive.
Does Chemo Age You? – Oncology Support Network
According to the research linked below, both polyphenols and vitamin D have been shown to counteract aging. Polyphenols such as
- Curcumin
- Resveratrol and
- Green Tea
demonstrate many beneficial properties in addition to slowing senescence. Vitamin D can also slow cellular aging, according to research.
I am a long-term MM survivor. Living with MM since my diagnosis in early 1994 has taught me that conventional oncology is only a piece of the MM picture.
Email me at David.PeopleBeatingCancer@gmail.com to learn more about managing MM with both conventional and non-conventional therapies like polyphenols.
Good luck,
David Emerson
- MM Survivor
- MM Cancer Coach
- Director PeopleBeatingCancer
The Antiaging Potential of Dietary Plant-Based Polyphenols: A Review on Their Role in Cellular Senescence Modulation
Abstract
Aging is a complex biological process characterized by a progressive decline in physiological functions and an increased risk of chronic diseases. A key mechanism of this process is cellular senescence, the permanent arrest of the cell cycle in response to stress or damage, which contributes to the accumulation of dysfunctional cells in tissues.
Recent research has highlighted the role of polyphenols, bioactive compounds present in numerous plant-based foods, in positively modulating these processes. Polyphenols exert antioxidant effects, regulate gene expression and improve mitochondrial function, helping to delay cellular aging and prevent age-related diseases.
In addition, some polyphenols exhibit senolytic properties, selectively eliminating senescent cells and promoting tissue regeneration. This review summarizes the current evidence on the effects of polyphenols on aging and cellular senescence, exploring the underlying molecular mechanisms and discussing their potential in nutritional strategies aimed at promoting healthy aging…
Polyphenols
Structurally, polyphenols are characterized by one or more aromatic rings and two or more hydroxyl groups. They are widely found in vegetables, fruits, cereals, red wine, tea, and related derived foods and beverages [18].
Dietary polyphenols exhibit a range of beneficial biological activities, including:
- antioxidant,
- anti-inflammatory,
- anticancer,
- antimicrobial,
- and neuroprotective effects [19].
Based on their chemical structure, dietary polyphenols can be classified into five major groups: phenolic acids (e.g., hydroxybenzoic and hydroxycinnamic acids), stilbenes, lignans, flavonoids (such as flavanols, isoflavones, anthocyanins, flavanones, flavones, and flavonols), and tannins [20].
Compounds within each subclass have shown potential health-promoting properties when regularly consumed as part of a balanced diet…
Conclusions
Targeting SCs represents a promising strategy to counteract age-related diseases. Naturally occurring flavonoids, with senolytic and senomorphic properties, have demonstrated efficacy in preclinical models by modulating the SASP and promoting tissue homeostasis.
Future research should focus on improving delivery systems and conducting robust clinical trials to validate their therapeutic potential in humans and support the development of effective senotherapeutics.
A new study suggests that Vitamin D supplements may help preserve telomeresexternal link —the DNA caps at the ends of chromosomes that maintain genetic stability and protect against cell death. If the findings can be replicated, researchers say, they could point to a “promising strategy” for countering biological aging.
Can myeloma patients slow aging Can myeloma patients slow aging Can myeloma patients slow aging