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Cancer-related Fatigue in Myeloma

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There isn’t a day that goes by where I don’t read a comment about cancer-related fatigue in myeloma. A myeloma patient is struggling with this side effect of chemotherapy to manage their incurable blood cancer. Myeloma patients desperate for help managing side effects from their treatment.

Sadly, the most frequently offered solutions are moderate exercise, coffee or even ritalin. No, a good night’s sleep does not help cancer-related fatigue in myeloma.

Interestingly, the content linked below offers traditional chinese medicine called Bushen-Jianpi decoction.


What are the health benefits of Bushen-Jianpi decoction?

While scientific research is ongoing, some studies and traditional uses suggest potential health benefits:

1. Improved Digestive Health

  • Spleen Strengthening: BJD is traditionally used to enhance spleen function, which, in TCM, is responsible for digestion and nutrient absorption.
  • Relief of Gastrointestinal Symptoms: It may alleviate symptoms like bloating, diarrhea, and poor appetite by supporting digestive processes.

2. Enhanced Kidney Function

  • Kidney Nourishment: It is used to address kidney deficiencies, which, in TCM, are linked to fatigue, low back pain, and reduced vitality.
  • Hormonal Balance: Some studies suggest BJD may regulate hormones by improving kidney function, which, in TCM, is tied to reproductive health.

3. Immune System Support

  • Boosting Qi and Immunity: By strengthening the spleen and kidney, BJD is believed to fortify the immune system, helping the body resist illness.

4. Fatigue and Energy Enhancement

  • Reduction of Chronic Fatigue: BJD is commonly prescribed for people experiencing chronic fatigue due to kidney and spleen deficiency.

5. Potential Role in Treating Chronic Conditions

  • Diabetes Management: Some studies suggest BJD might help regulate blood sugar levels and improve metabolic health.
  • Liver Fibrosis: Research indicates potential protective effects against liver damage and fibrosis.
  • Menopausal Symptoms: In TCM, kidney deficiencies are linked to menopausal symptoms, and BJD might provide relief by addressing this imbalance.

6. Anti-Inflammatory and Antioxidant Properties

  • Reduction of Inflammation: Some herbal components in the decoction may possess anti-inflammatory effects.
  • Oxidative Stress: The formula might help reduce oxidative stress, protecting cells from damage.

Common Ingredients in Bushen-Jianpi Decoction

The specific composition can vary, but it typically includes herbs such as:

  • Dang Shen (Codonopsis root): Supports energy and digestion.
  • Huang Qi (Astragalus root): Boosts immunity and Qi.
  • Bai Zhu (Atractylodes root): Enhances spleen function.
  • Shu Di Huang (Prepared Rehmannia root): Nourishes kidney Yin.
  • Shan Yao (Chinese yam): Supports spleen and kidney health.


When I was told that I was end-stage after 3.5 years of surgery, chemo and radiation, I decided to try other forms of medicine.

The shops in the video above look like the shop I went to in the Chinatown here in Cleveland, Ohio. I don’t know if you have a Chinatown were you live but good luck in finding the herbs listed below.

Email me a David.PeopleBeatingCancer@gmail.com if you have questions about multiple myeloma

Good luck,

David Emerson

  • MM Survivor
  • MM Cancer Coach
  • Director PeopleBeatingCancer

Bushen-Jianpi decoction

A traditional Chinese medicine (TCM) that is used for Yin deficiency of the liver, kidney and spleen, with potential immunomodulating and antineoplastic activities. Bushen-Jianpi decoction (BSJPD; BJD) consists of various herbs, including, but not limited to:
  • Radix Codonopsis (Dang Shen),
  • Fructus Lycii (the fruit of Chinese wolfberry),
  • Rhizoma Atractylodis Macrocephalae (Baishu; Bai Zhu),
  • Fructus Ligustri Lucidi,
  • Cuscuta chinensis (Chinese dodder) seed,
  • and Psoralea corylifolia Linn.
As a TCM, Bushen-Jianpi is used as an antineoplastic agent as it is thought to invigorate the spleen and tonify the kidney, which presumably prevents or treats a variety of cancers.
Upon administration of Bushen-Jianpi decoction, the ingredients in the decoction may affect signaling pathways involved in carcinogenesis and enhance the immune system by increasing the levels of numerous cytokines and a variety of immune cells, such as cytotoxic T lymphocytes (CTLs), natural killer cells (NKs) and macrophages. It may also reduce the expression of various proteins involved in tumorigenesis.”

Effects of Jianpi Therapy for cancer-related fatigue:a Meta-Analysis of Randomized Controlled Trials

“The Jianpi therapeutic strategy in traditional Chinese medicine aims to enhance the spleen’s digestive function and overall wellness. It has shown promise in improving cancer-related fatigue (CRF).

This research systematically evaluates the effectiveness of Jianpi therapy in reducing fatigue in cancer patients through a meta-analytic review.

Methods: An exhaustive search was performed within PubMed, Embase, Web of Science, Cochrane Library, SinoMed, Wanfang Data, China Science and Technology Journal Database, and China National Knowledge Infrastructure (CNKI) for randomized controlled trials concerning the application of Jianpi therapy to address CRF…

The Cochrane Risk of Bias Assessment Tool 2.0 was utilized to assess the potential biases within the studies.A comprehensive analysis was performed on 45 eligible studies, all of which were conducted within China and encompassed a total of 3,596 participants.

The meta-analysis indicated that Jianpi decoction alone exhibited the most significant improvement in the proportion of CD4 cells (SMD=1.34, 95% CI 0.54 to 2.31, P<0.001) and hemoglobin (MD=7.45, 95% CI 4.18 to 10.72, Z=4.47, P<0.001), while also more significantly reducing Piper Fatigue Scale scores (SMD=-2.05, 95% CI -2.71 to -1.39, P<0.001).

The combined therapy, which integrated Jianpi therapy with standard care, demonstrated the greatest advantage in enhancing the proportion of CD3 cells (SMD=1.25, 95% CI 0.46 to 2.04, P<0.001).

Furthermore, Jianpi therapy was found to be effective in lowering tumor necrosis factor-alpha levels P<0.001) and concurrently enhancing interferon-gamma (MD=5.15, 95% CI 3.20 to 7.09, P=0.002), interleukin-2 (MD=8.37, 95% CI 6.14 to 10.59, P<0.001).

Our research indicates that Jianpi therapy effectively alleviates CRF, reduces inflammation, and strengthens immune function. However, further high-quality, multicenter randomized controlled trials are essential to confirm these findings and strengthen the evidence.”

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