Download the FREE ebook "Beating Myeloma: If I Knew Then What I Know Now" and arm yourself with the information about autologous stem cell transplantation, treatment options, and side effects that I wish I had known about when I began treatment.
We get it. Multiple Myeloma is incurable. The real problem of a multiple myeloma diagnosis isn’t achieving remission after we are diagnosed. The challenge is that almost every survivor lives his/her life from remission to relapse, from peak to valley. As soon as we achieve remission, we fear the day when our myeloma returns. Consider the idea of the cancer stem cell.
Therefore, all mm survivors ask ourselves “Why is it practically a medical certainty that our myeloma will return? And what can we do about it???”
Whether you consider your coming cancer experiences to be a battle or a chess match, it is critical that you understand the basics of how your opponent functions.
I am both a multiple myeloma survivor and multiple myeloma cancer coach. I need to understand cancer issues like the cancer stem cell theory.
What does the CSC theory mean for multiple myeloma patients, survivors and caregivers? I can only speak as a MM survivor.
My belief is that while I achieved complete remission from my MM in 4/99, I live my life as if I have MM cancer stem cells running around inside me. There are always going to be microscopic cancer stem cells hiding inside me ready to form lesions in my bone marrow.
Therefore I practice lifestyle therapies that evidence-based research says kills multiple myeloma. I live an evidence-based, anti-myeloma lifestyle through nutrition, supplementation, bone health, lifestyle, mind-body therapies and more. Think of it like low-dose, maintenance therapy. But non-toxic.
To learn more about evidence-based but non-toxic multiple myeloma therapies, scroll down the page, post a question or comment and I will reply to you ASAP.
“THE IMPLICATIONS of a stem cell model of cancer for the way we understand as well as treat malignancies are clear and dramatic. Current therapies take aim against all tumor cells, but our studies and others have shown that only a minor fraction of cancer cells have the ability to reconstitute and perpetuate the malignancy. If traditional therapies shrink a tumor but miss these cells, the cancer is likely to return…
Treatments that specifically target the CSCs could destroy the engine driving the disease, leaving any remaining nontumorigenic cells to eventually die off on their own.”
“The bone marrow microenvironment provides to MM CSCs self-renewal, survival and drug resistance thanks to the presence of normal and cancer stem cell niches. The niches and CSCs interact each other through adhesion molecules and the interplay between ligands and receptors activates stemness signaling (Hedgehog, Wnt and Notch pathways). MM CSCs are also supposed to be responsible for drug resistance that happens in three steps from the initial cancer cell homing microenvironment-mediated to development of microenvironment-independent drug resistance.”
“Researchers at the University of Southern California (USC) recently made significant strides toward settling a decades-old debate centering on the role played by stem cells in cancer development. According to the study’s findings, genes that are reversibly repressed in embryonic stem cells are over-represented among genes that are permanently silenced in cancers; this link lends support to the increasingly discussed theory that cancer is rooted in small populations of stem cells.”