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Cannabis Manages Myeloma Pain

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Medical cannabis manages myeloma pain according to the research linked below. When I say “myeloma pain,” I mean pain that occurs from the damage caused by the cancer itself, as well as pain caused by therapies meant to manage myeloma.

According to research, almost all MM survivors suffer pain of some kind, usually bone pain. 

The issue then becomes, what do MM survivors do to live with their pain?



I am a long-term MM survivor.  I deal with many different long-term side effects from my conventional therapies. I rely on several pain management therapies, including:

  • Medical cannabis
  • Acupuncture 
  • Moderate Exercise
  • Nutritional Supplementation 

and more. While I have used opioids before, I admit that I try to keep them to a minimum, if at all.

David Emerson

  • MM Survivor
  • MM Cancer Coach
  • Director PeopleBeatingCancer

Patterns, Efficacy, and Cognitive Effects of Medical Cannabis Use in Chronic Musculoskeletal Pain Patients

Abstract

Background: Medical cannabis (MC) is being used with greater frequency in the management of chronic pain. While its efficacy in pain relief is promising, questions about patterns of use and efficacy warrant further investigation. This study aimed to evaluate long-term MC use patterns, perceived efficacy, and its impact on cognition among patients with chronic musculoskeletal noncancer pain.

Methods: This prospective study included patients who were certified for MC between October 2022 and December 2024. Patients who were certified for MC under Pennsylvania state guidelines for a minimum of one year were tracked, yielding 129 patients for analysis. The patients completed an Inventory of Medical Cannabis Use (IMCU) questionnaire assessing usage patterns, dosage knowledge, efficacy, cognitive effects, and tolerance changes. The responses were collected in a password-protected database.

Results: A total of 77.5% of patients reported using MC daily or near daily. Topical formulations were most frequently used (63.6%). Approximately half of the respondents were uncertain of their exact tetrahydrocannabinol/cannabidiol (THC/CBD) dosage, with a median oral dose of 10 mg recorded among those who provided estimates.

High levels of perceived efficacy were reported, with over 93% of respondents agreeing or strongly agreeing that MC improved their primary symptoms.

Cognitive and motor effects were minimal for most users, with 72.1% reporting no impact. Furthermore, 79.8% of respondents indicated stable usage patterns over the prior three months, and very few reported a need or external suggestion to reduce MC intake.

Conclusions: Long-term MC use is a stable and well-tolerated option for managing chronic musculoskeletal pain, with high patient-reported efficacy and minimal cognitive impact. These findings support its role in pain management while highlighting the need for further research on optimal dosing and long-term safety.

What is Musculoskeletal pain”

Musculoskeletal pain is a broad term that describes pain felt in the bones, muscles, ligaments, tendons, and other tissues that support the body’s movement. It can range from mild discomfort to debilitating pain, affecting daily activities and quality of life. 

Causes of Musculoskeletal Pain: 
    • Injuries: Fractures, sprains, strains, and muscle tears are common causes of acute musculoskeletal pain. 
    • Overuse: Repetitive movements or activities can lead to inflammation and pain in muscles, tendons, and ligaments. 
  • Age-related changes: Arthritis, osteoporosis, and other age-related conditions can cause chronic musculoskeletal pain. 
  • Underlying conditions: Conditions like fibromyalgia, inflammatory diseases, and autoimmune disorders can also cause widespread musculoskeletal pain. 
  • Poor posture and body mechanics: Improper posture or body mechanics can strain muscles and joints, leading to pain. 
  • Infections: In some cases, infections can cause pain in the joints or bones. 
  • Tumors: While rare, bone tumors can cause musculoskeletal pain. 
Symptoms of Musculoskeletal Pain:
  • Pain: The most common symptom is pain, which can range from mild to severe, localized to a specific area or widespread. 
  • Stiffness: Muscles and joints may feel stiff, making it difficult to move or bend. 
  • Weakness: Pain and inflammation can cause muscle weakness, making it difficult to perform everyday tasks. 
  • Reduced range of motion: Pain and stiffness can limit the ability to move joints through their full range of motion. 
  • Fatigue: Pain and discomfort can interfere with sleep, leading to fatigue and decreased energy levels. 
  • Swelling, warmth, or redness: Inflammation can cause swelling, warmth, or redness in the affected area. 
  • Joint noises: Popping or grinding sounds may be heard in affected joints. 

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