Cardiovascular Disease in Lung Cancer Survivors

How can you reduce cardiovascular disease in Lung Cancer Survivors? By living a heart-healthy lifestyle through nutrition, supplementation, and lifestyle therapies.

There is growing research showing that lung cancer survivors experience higher rates of cardiovascular disease (CVD) than people without a cancer history.

The research below indicates that lung cancer survivors — like other cancer survivors — have a significantly higher risk of cardiovascular disease than people without a cancer history. This increased risk persists long after cancer treatment and involves multiple cardiovascular outcomes, including CHD, stroke, and heart failure.

Shared risk factors, treatment-related cardiotoxicity, and cancer-related biological changes all appear to play roles. These findings underscore the importance of integrated survivorship care that addresses heart health alongside cancer monitoring.

I have posted the video below because it explains the problem of cardiovascular disease in lung cancer survivors, and it explains what to do about it.

Cardiovascular Disease in the Modern Cancer Survivor

I am a long-term cancer survivor of an incurable blood cancer called multiple myeloma. I was diagnosed with chemotherapy-induced cardiomyopathy in late 2015, fully 15 years after my oncologist prescribed cardiotoxic chemotherapy to me.

The cardio-oncologist prescribed a common heart medication called metoprolol. I think lung cancer survivors may benefit from conventional health therapies. However, I had a reaction to the medication and disconintued taking it. I researched evidence-based, heart healthy therapies that I could pursue on my own such as nutrition, exercise, and supplementation such as CoQ10, curcumin, omega-3 fatty acids, etc.

I was able to lower my blood pressure, increase my ejection-fraction and stabilize my heart health. I have been able to live without conventional heart medication since 2015.

Again, conventional cardiology should be a part of your long-term survivor plan. I am just saying that evidence-based non-conventional heart health should be included too.

Scroll down the page, post a question or a comment if you’d like to learn more about cancer survivorship.

Good luck,

David Emerson

Cancer Survivor
Cancer Coach
Director PeopleBeatingCancer

Increased risk of coronary heart disease and stroke in lung cancer survivors: A Korean nationwide study of 20,458 patients

Abstract

Objectives: With advances in lung cancer treatments, the number of lung cancer survivors has increased. As cardiovascular diseases (CVD) are some of the major causes of non-cancer deaths, CVD management is an integral part of cancer survivorship care. However, there is sparsity of data on cardiovascular risk in lung cancer survivors who underwent lung cancer surgery. We aimed to compare the incidence of CVD between lung cancer survivors and the general non-cancer population…

Results: A total of 20,458 lung cancer patients undergoing lung cancer surgery were compared to 27,321 non-cancer control subjects. Lung cancer survivors showed a greater risk for all cardiovascular (CV) events (adjusted hazard ratio [aHR] = 1.27, 95% confidence interval [CI]: 1.19-1.36), CHD (aHR = 1.26, 95% CI: 1.16-1.36), and IS (aHR = 1.22, 95% CI: 1.07-1.39).

Chemotherapy and radiotherapy were associated with an increased risk of CV events, CHD, and MI. Lung cancer survivors who were CV event-free for one year, and up to three years, were still at a higher risk for all CV events compared to the non-cancer control population.

Conclusions: Lung cancer survivors showed an increased risk of CHD and IS compared with the general non-cancer population. Therefore, paying careful attention to cardiovascular risk in lung cancer survivors is suggested, especially for those who receive chemotherapy and/or radiotherapy, in order to ensure both early and long-term survivorship.

Risk of cardiovascular disease among cancer survivors: systematic review and meta-analysis

Background: There have been conflicting studies on the associations between cancer and cardiovascular disease (CVD) risk. The hypothesis of this meta-analysis was to investigate whether cancer survivors had an increased risk of CVD compared to those without cancer based on population-based cohort studies…

Findings: A total of 160 population-based cohort studies involving 49,395,865 participants (9,092,869 cancer survivors vs. 40,302,996 non-cancer controls) were identified. Overall, the HR for CVD in cancer survivors was 1.47 [95% CI, 1.33-1.62] compared with that in non-cancer controls. Cancer increased the risk of all 17 CVD subtypes, with cancer having the greatest effect on venous embolism, thrombosis or thrombophlebitis (HR, 3.07 [2.03-4.65]) and the least on ischemic heart disease (HR, 1.13 [1.03-1.24]). The increased risk of CVD was consistently shown in cancer survivors of brain, hematological, respiratory, male genital, and breast cancers, whereas no significant higher CVD risk was observed for other cancer types. Elevated risk of CVD was consistently shown in subgroup analyses of study design, age at cancer diagnosis, sex, location, follow-up duration, control, disease diagnosis, and therapy. Male and younger cancer survivors had elevated risk of CVD than female and older cancer survivors.

Interpretation: This meta-analysis provides an up-to-date comprehensive global overview that cancer survivors had increased risk of CVD and 17 CVD subtypes than non-cancer controls. CVD risk evaluation and management need to be prioritized in cancer survivors, particularly among male, younger, and specific cancer survivors (brain, hematological, respiratory, male genital, and breast). This study provides supporting evidence that may inform future updates to guidelines for CVD prevention in cancer survivors, highlighting its public health relevance.

cardiovascular disease in Lung Cancer Survivors cardiovascular disease in Lung Cancer Survivors cardiovascular disease in Lung Cancer Survivors

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Cardiovascular Disease in Lung Cancer Survivors

Cardiovascular Disease in the Modern Cancer Survivor

David Emerson

Increased risk of coronary heart disease and stroke in lung cancer survivors: A Korean nationwide study of 20,458 patients

Abstract

Risk of cardiovascular disease among cancer survivors: systematic review and meta-analysis

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