Diagnosed with SMM, SPB, or MGUS?
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Category Archives for Pre-Myeloma
Smoldering Multiple Myeloma- What’s My Risk of Multiple Myeloma?
“SMM is distinct from monoclonal gammopathy of undetermined significance (MGUS) due to a higher risk of progression to active MM disease. For patients at high-risk of progressing from SMM…” A
Continue readingSmoldering Multiple Myeloma- Early Treatment?
“…there is a need to better understand the significant heterogeneity in SMM and to identify the patients who benefit the most from early treatment from those who can safely defer treatment.” I
Continue readingDiagnosis of Asymptomatic Malignant Multiple Myeloma???
“Often, no symptoms (of multiple myeloma) are noticed initially. As it progresses, bone pain, anemia, kidney dysfunction, and infections may occur.” I have recently been diagnosed with asymptomatic
Continue readingSingle Plasmacytoma, MGUS or SMM? To treat or watchful waiting?
Single Plasmacytoma, Smoldering Multiple Myeloma (SMM) and Monoclonal Gammopathy of Undetermined Significance (MGUS)- Asymptomatic aka no signs or symptoms? A diagnosis of a single plasmacytoma (SP),
Continue readingSauna as MGUS Therapy
“As hyperthermia is nonmyelosuppressive and can potentiate the tumoricidal effects of radiation, chemotherapy, and immunotherapy, its use as part of a multimodality treatment approach is attractive.” Hi
Continue readingIt’s Either Smoldering Multiple Myeloma or Multiple Myeloma
If you are not young, early stage (MM) and low-risk then, according to the research below, your average first remission will be about 2-3 years and your OS will be about the average 5-7 years. Hi David-
Continue readingMGUS Progressing to Multiple Myeloma- Obesity and Inflammation?
“…based on 29 cases that progressed to MM or other LP diseases later in life, our study found midlife obesity to be a risk factor for progression among individuals diagnosed with MGUS.” Hi
Continue readingPrevent SMM from becoming Multiple Myeloma
“However, most patients eventually relapse and often demonstrate multiple drug resistance. Therefore there is still an urgent and unmet need to define the molecular mechanisms of resistance for available
Continue readingHigh FLC Ratio, No M-spike, No Crab- MGUS? Risk of MM?
treatment of MGUS/SMM patients with curcumin resulted in an improvement in markers of disease progression (i.e., free light-chain ratio (rFLC), paraprotein levels, percentage plasma cells) in some patients
Continue readingHigh Risk Smoldering Multiple Myeloma? To Treat or To Wait?
A recent update confirmed an overall survival advantage after a median follow-up of more than six years,”How can overall survival be measured in pre-Multiple Myeloma (MGUS, SMM)? The oncologist in
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