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Category Archives for Pre-Myeloma

Solitary Plasmacytoma

The most common of these is solitary plasmacytoma of bone (SPB), accounting for 3–5% of all plasma cell malignancies. Prognostic Nomogram for Predicting Overall Survival of Solitary Bone Plasmacytoma

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Smoldering Multiple Myeloma-

Smoldering multiple myeloma is an intermediate stage between MGUS and myeloma and is associated with a higher risk of progression of approximately 10% year. Smoldering Multiple Myeloma (SMM) is a term

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Does Smoldering Multiple Myeloma Always Progress to full MM?

“SMM is distinct from monoclonal gammopathy of undetermined significance (MGUS) due to a higher risk of progression to active MM disease. For patients at high-risk of progressing from SMM…” No.

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Living with MGUS

“…enabled detection of MGUS in 5.1% of the members of the community tested in the Olmsted County screening study cohort in the age group of 50 years or older.” According to the research

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MGUS Diagnosis

Monoclonal Gammopathy of Undetermined Significance is not cancer. MGUS is pre-cancer or a stage before full-blown multiple myeloma.  MGUS aka monoclonal gammopathy of undetermined significance is a

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Smoldering Multiple Myeloma- First Steps?

“We’ve seen data before by the Mayo Clinic and the University of North Carolina showing that multiple myeloma patients who are seen by a myeloma specialist live longer…” Hi David- I

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Solitary Plasmacytoma on Rib w/ Amyloidosis

“The Bortezomib/Dexamethasone regimen induced high rates of rapid hematologic and organ responses in AL amyloidosis patients.” Hi David- My wife is newly diagnosed with a solitary plasmacytoma

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Chemo does NOT help Smoldering Myeloma

Based on the current evidence, early treatment didn’t significantly affect mortality and response rate… The diagnosis of an incurable cancer like multiple myeloma is awful. Patients feel as if

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Monoclonal Gammopathy of Undetermined Significance (MGUS) and HPV

What Does It Mean for MGUS and HPV to be “Associated?” Actionable Non-Toxic Therapy is For the Pre-Myeloma Patient- The study linked and excerpted below cites a small study of MGUS patients,

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MGUS, SMM Neuropathy

“Peripheral Neuropathy is not only induced by treatment, as studies have found percentages of PN in newly diagnosed MM patients in 13% … Vitamin D Deficiency Getting enough, but not too much,

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Solitary Plasmacytoma of Bone- Q & A

“”Solitary plasmacytoma (SP) is an early-stage plasma cell malignancy that is in between monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma (MM) along the spectrum

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High-Risk SMM- Therapy

Hi David- Thank you for such an informative site! There is so much to learn with Multiple Myeloma. At 44, I was diagnosed with Monoclonal Gammopathy of Undetermined Significance (MGUS).  Last year at

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