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My diagnosis of multiple myeloma in early ’94 led to induction chemotherapy, stem cell mobilization and an autologous stem cell transplant all in 1995. Fifteen years later, in late 2010, I developed atrial fibrillation (Afib) and I was diagnosed with Chemotherapy-induced cardiomyopathy-(CIC).
The damage (CIC) done to my heart should come as no surprise once you study the short, long-term and late stage side effects caused by the cardiotoxic chemotherapies prescribed for my treatments, listed below.
CIC diagnosed 15 years after active therapy is my definition of a late stage side effect.
This blog post will focus on CIC specifically however I have to manage a host of heart problems all related to the cardiotoxic chemotherapies that I underwent listed below.
Since I developed CIC, Afib, etc. in late 2010, I have come to focus on specific heart-health issues- specifically an aortic aneurysm, enlarged aortic root, weakened left ventricle and enlarged left atrium. While I it is clear that cardio-toxic chemotherapy did serious damage my heart, I have to wonder is Marfan’s Syndrome, a condition that runs in my family, may also be a contributing factor.
A bit more than half of CIC survivors die within 10 years of their diagnosis. The standard-of-care, FDA approved treatment for CIC is/are ACE-inhibitors, ARBs and beta blockers (BB).
When I was first diagnosed with CIC in late 2010, I too was prescribed a standard-of-care therapy-metoprolol. After only a day or two on the medication I felt awful (fatigue, shortness of breath) and I chose to discontinue taking this drug. I chose to pursue evidence-based, non-toxic, non-conventional therapies. The dozen or so blog posts linked below document years of struggling with CIC, Afib, BP, etc.
My issue then, was to manage my heart health as well as my CIC, Afib, blood clot, ejection fraction (EF), Aortic aneurysm, etc. and live a normal quality-of-life (QOL) without toxic medications.
It took a few years to figure out what I was doing but the results of five echocardiograms over six years- 2015-2021, as of my echocardiogram in June of 2021- are listed below.
several other supplements.
In short, all metrics of my CIC is/are stable or have improved since my diagnosis of CIC in 12/2010.
When T.V. commercials say “when diet and exercise aren’t enough” they are enough in my case. I am NOT saying that all use of toxic heart, BP, etc. meds are bad. I am saying that conventional therapies often have more short, long-term and late stage side effects than your M. D. will tell you about and I am saying that evidence-based, non-toxic heart therapies should be pursued first.
You must understand ALL of the pros and cons, the risks and rewards to any therapy. And if you can’t control something, then by-all-means, use a conventional therapy.
Blog Posting about Chemotherapy-Induced Cardiomyopathy-
I’ve spent years researching and writing about chemotherapy-induced cardiomyopathy for years- the good, bad and the ugly.
If you’ve undergone cardiotoxic chemotherapy regimens, consider evidence-based, non-toxic therapies shown to heal chemotherapy-induced Cardiomyopathy. Scroll down the page to learn more.
“Doctors turn to professional guidelines to help them identify the latest thinking on appropriate medical treatments, but a study out Friday finds that in the realm of heart disease, most of those guidelines aren’t based on the highest level of evidence…
A paper in JAMA, the journal of the American Medical Association, that was released online ahead of print, finds that less than 10 percent of cardiovascular guidelines are based on the most carefully conducted scientific studies, known as randomized controlled trials. A lot of the rest are based on much weaker evidence…”
All have improved-
6/2021 Left Ventricle: The left ventricular systolic function is low normal, with an estimated ejection fraction of 50-55%.
2/2020- Left Ventricle: The left ventricular systolic function is low normal, with an estimated ejection fraction of 50-55%.
10/2018- Left Ventricle: The left ventricular systolic function is mildly decreased, ejection fraction of 40-45%.
9/2016- Left Ventricle: The left ventricular systolic function is mildly to moderately decreased, with an estimated ejection fraction of 40-45%.
10/2015-The left ventricular systolic function is mildly decreased, with an estimated ejection fraction of 40-45%.
2/2020 The aortic root is abnormal. There is moderate dilatation of the ascending aorta. There is severe dilatation of the aortic root.
10/2018- The aortic root is abnormal. There is moderate dilatation of the ascending aorta. There is moderate dilatation the aortic root.
09/2016- The aortic root is abnormal. There is moderate dilatation of the ascending aorta. There is severe dilatation of the aortic root.
10/2015- The aortic root is abnormal. There is moderate dilatation of the ascending aorta. There is severe dilatation of the aortic root. Maximal diameter of aortic root is 5.3 cm