Recently Diagnosed or Relapsed? Stop Looking For a Miracle Cure, and Use Evidence-Based Therapies To Enhance Your Treatment and Prolong Your Remission
Multiple Myeloma an incurable disease, but I have spent the last 25 years in remission using a blend of conventional oncology and evidence-based nutrition, supplementation, and lifestyle therapies from peer-reviewed studies that your oncologist probably hasn't told you about.
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Chemotherapy-induced Nausea and Vomiting
Chemotherapy-induced nausea and vomiting is one of the most common side effects of the many short-term side effects that may challenge the MM patient. The good news is that chemo-induced nausea is a short-term problem.
In my experience, conventional therapies were not very effective at managing chemotherapy-induced nausea and vomiting, so I thought I would post info about medicinal plants as well as some home remedies that may help MM patients manage their chemotherapy-induced nausea and vomiting.
My approach to most therapies is to combine both conventional and non-conventional therapies.
Home Remedies for Cancer Treatment-Induced Nausea
When I was first diagnosed with MM, I thought the only issue was how to effectively manage MM. It turns out that there is a lot more to our challenge than that.
Please don’t be surprised if your oncologist doesn’t mention any of the therapies above. Cannabis, for example, is still illegal, federally, in the United States, and conventional medicine won’t discuss it, no matter how effective it might be.
Email me at David.PeopleBeatingCancer@gmail.com to learn more about managing MM with both conventional and non-conventional therapies.
Good luck,
David Emerson
- MM Survivor
- MM Cancer Coach
- Director PeopleBeatingCancer
Medicinal Plants for Chemotherapy-Induced Nausea and Vomiting: A Systematic Review of Antiemetic, Chemosensitizing, and Immunomodulatory Mechanisms
Background: Chemotherapy-induced nausea and vomiting (CINV) is a major burden for cancer patients, often poorly managed by conventional antiemetics, prompting exploration of medicinal plant therapies for better supportive care.
Objective: This systematic review critically evaluates medicinal plants for CINV, detailing bioactive compounds, diverse antiemetic mechanisms, and promising chemosensitizing and immunomodulatory properties.
Methods: A comprehensive literature search and critical analysis of studies investigating medicinal plants for CINV were performed.
Key Findings: This review synthesizes evidence for 22 botanicals.
- Ginger (gingerols, shogaols) acts via 5-hydroxytryptamine 3 (5-HT₃) receptor antagonism and substance P/neurokinin-1 (NK-1) inhibition, and offers chemosensitization by downregulating P-glycoprotein.
- Cannabis (THC, CBD) modulates the endocannabinoid system and 5-HT₃ receptors for CINV relief and may enhance chemotherapy sensitivity.
- Mint (menthol, menthone) relaxes gastrointestinal smooth muscle and offers anti-inflammatory benefits.
- Chamomile (apigenin) has antispasmodic/anxiolytic effects; its apigenin also sensitizes cancer cells to chemotherapy.
- Turmeric (curcumin) acts on neurotransmitter systems, offers potent anti-inflammatory/antioxidant effects, and boosts chemosensitivity via NF-κB/P-gp modulation.
Plants like Pinellia ternata, lemon, fennel, and licorice show varied mechanisms (gastrointestinal regulation, anti-inflammatory, neurotransmitter modulation).
Many botanicals show chemosensitizing (inhibiting efflux pumps, promoting apoptosis) and immunomodulatory (affecting cytokines, immune cells) properties. Synergistic plant combinations (eg, ginger with P. ternata or turmeric) are noted for enhanced efficacy and safety.
Conclusion: Medicinal plants offer a compelling, multi-targeted approach for CINV management, with potential beyond symptomatic relief via their antiemetic, chemosensitizing, and immunomodulatory actions. Rigorous clinical trials are needed to integrate these botanicals into evidence-based supportive cancer care…
Medicinal Plants That Can Be Used in Combination
Although individual medicinal plants have demonstrated efficacy in the management of CINV, traditional medicine often emphasizes the synergistic potential of plant combinations to enhance therapeutic outcomes. This section explores several promising combinations, underscoring their potential for synergistic effects in alleviating CINV while calling for further research to validate and optimize their clinical application…
Conclusion
Medicinal plants present a compelling, multi-targeted therapeutic option that may enhance current strategies for CINV management, offering potential beyond symptomatic relief.
Among the 22 plants studied, ginger, cannabis, and turmeric show the strongest evidence and more prominent antiemetic efficacy in clinical and preclinical models and exert anti-inflammatory effects.
Their documented antiemetic, chemosensitizing, and immunomodulatory actions strongly support their further investigation. Future research should prioritize dose standardization, comprehensive safety profiling, and large-scale clinical trials to guide their evidence-based integration into oncology care”
Chemotherapy-induced nausea and vomiting Chemotherapy-induced nausea and vomiting