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I have chronic atrial fibrillation aka A-Fib as a result of aggressive cardiotoxic chemo and a diagnosis of chemotherapy-induced cardiomyopathy in 12/10.
A-Fib and cardiomyopathy are a pretty common long-term side-effect of high-dose chemotherapy. I’ve read that I can live a live an active, normal life (EveryDay Health) if I take care of my heart, reduce my risk of stroke and avoid congestive heart failure…
I’ve posted some of my echocardiogram results from the past five (5) echos over the past six years. I have achieved the improvements without toxic therapies of any kind.
The study linked and excerpted below states that Coq10 supplementation (100mg daily) improves ejection fraction. Not to get too technical but since my heart rhythm is way off, blood flow both in and out is also way off. Coq10 keeps the heart muscle strong keeping the ejection fraction up.
Coq10 supplementation is an easy, cost-effective therapy.
I am a cancer survivor and cancer coach. For more information about short, long-term and late stage side effects of aggressive chemotherapy, scroll down the page, post a question or comment and I will reply ASAP.
“The objective of this meta-analysis was to evaluate the impact of CoQ₁₀ supplementation on the ejection fraction (EF) and New York Heart Association (NYHA) functional classification in patients with CHF…
Supplementation with CoQ₁₀ resulted in a pooled mean net change of 3.67% in the EF… Subgroup analyses showed significant improvement in EF for crossover trials, trials with treatment duration ≤12 wk in length, studies published before 1994, and studies with a dose ≤100 mg CoQ₁₀/d and in patients with less severe CHF. These subgroup analyses should be interpreted cautiously because of the small number of studies and patients included in each subgroup…
“The burden of cardiovascular and metabolic diseases is increasing with every year. Although the management of these conditions has improved greatly over the years, it is still far from perfect. With all of this in mind, there is a need for new methods of prophylaxis and treatment.
Coenzyme Q10 (CoQ10) is an essential compound of the human body. There is growing evidence that COQ10 is tightly linked to cardiometabolic disorders. Its supplementation can be useful in a variety of chronic and acute disorders. This review analyses the role of COQ10 in hypertension, ischemic heart disease, myocardial infarction, heart failure, viral myocarditis, cardiomyopathies, cardiac toxicity, dyslipidemia, obesity, type 2 diabetes mellitus, metabolic syndrome, cardiac procedures and resuscitation…
The prevalence of the Atrial Fibrillation (AF) and HF are growing worldwide year by year . Atrial fibrillation can be called a typical atrial arrhythmia in patients diagnosed with HF. It is associated with an increase in morbidity and mortality [68, 69].
CoQ10 plays an important role in oxydative phosphorilation, producing ATP and this bioenergetic function is essential for proper heart functioning . Besides that, it has the property to scavenge ROS and antioxidant function …
Cardiomyopathy is a debilitating condition, which is associated with a high mortality and poor quality of life. There is extensive evidence from in vitro and animal studies that it is linked to increased oxidative stress .
Mice models of diabetic cardiomyopathy demonstrate that COQ10 decreases diabetes-induced left ventricular diastolic dysfunction; cardiomyocyte hypertrophy, fibrosis and apoptosis; expression of the atrial natriuretic peptide, connective tissue growth factor, pro-inflammatory mediators, and β-myosin heavy chain [80, 81]…
“Purpose-The aim of this systematic review was to summarize and evaluate the evidence available for oral supplementation with coenzyme Q10 (CoQ10) to improve the tolerability of cancer treatments
Results-Six studies were included in the review, including three randomized clinical trials and three nonrandomized clinical trials. Patients in five of six studies received anthracyclines. The results suggested that CoQ10 provides some protection against cardiotoxicity or liver toxicity during cancer treatment. However, because of inadequate reporting and analysis, as well as questionable validity of outcome measures, the results are not conclusive.
Conclusion- Suggestions that CoQ10 might reduce the toxicity of cancer treatments have not been tested by rigorous trials. Further investigations are necessary to determine whether CoQ10 can improve the tolerability of cancer treatments..”
All have improved-
6/2021 Left Ventricle: The left ventricular systolic function is low normal, with an estimated ejection fraction of 50-55%.
2/2020- Left Ventricle: The left ventricular systolic function is low normal, with an estimated ejection fraction of 50-55%.
10/2018- Left Ventricle: The left ventricular systolic function is mildly decreased, ejection fraction of 40-45%.
9/2016- Left Ventricle: The left ventricular systolic function is mildly to moderately decreased, with an estimated ejection fraction of 40-45%.
10/2015-The left ventricular systolic function is mildly decreased, with an estimated ejection fraction of 40-45%.
2/2020 The aortic root is abnormal. There is moderate dilatation of the ascending aorta. There is severe dilatation of the aortic root.
10/2018- The aortic root is abnormal. There is moderate dilatation of the ascending aorta. There is moderate dilatation the aortic root.
09/2016- The aortic root is abnormal. There is moderate dilatation of the ascending aorta. There is severe dilatation of the aortic root.
10/2015- The aortic root is abnormal. There is moderate dilatation of the ascending aorta. There is severe dilatation of the aortic root. Maximal diameter of aortic root is 5.3 cm