Myeloma- CoQ10 Cardiotoxicity

last year
/ Healthy Living Products Multiple Myeloma non-conventional therapies
/ By David Emerson
/ 9 COMMENTS

“clinical studies suggest that (the chemotherapy side effect) anthracycline–induced cardiotoxicity can be prevented by administering coenzyme Q10 during cancer chemotherapy

This blog post is at the top of my “I wish I knew then what I know now” list. According to the articles linked below, CoQ10 could have prevented the cardiotoxicity causing the multiple myeloma side effect that has permanently damaged my heart…

Anthracyclines (Daunorubicin (Daunomycin),Daunorubicin (liposomal),Doxorubicin (Adriamycin), Doxorubicin, Epirubicin, Idarubicin, Valrubicin) cause cardiotoxicty.
Coq10 supplementation during anthracycline administration prevents cardiotoxicity.
Most importantly, according to the evidence-based research linked and excerpted below, “Studies further suggest that Coq10 does not interfere with the antineoplastic action of anthracyclines and might even enhance their anticancer effects...”

I was diagnosed with multiple myeloma (MM) in early 1994. I underwent anthracyclines, cytoxan, busulphan and melphalan all in 1995. My oncologist said nothing about the possible short or long-term cardio toxicity of these chemotherapy regimens. Without warning I developed chronic Afib in late 2010 and chemotherapy-induced cardiomyopathy shortly thereafter.

Based on the studies linked below, this damage could have been prevented with CoQ10 supplementation. In case you’re wondering, no, the toxic chemotherapy is not why I’m here to write this blog post. I “failed” my conventional therapies in mid-1997 and was told that “nothing more could be done for me…”

If I were about to undergo cardiotoxic chemotherapy, Coq10 supplementation would be a no-brainer.

“Prevents cardiotoxicity and does not interfere with the cancer-killing action of the chemo.”

If you are about to undergo cardiotoxic chemotherapy, please read the studies linked below and consider supplementing with the brand of CoQ10 supplement that I take daily called Life Extension Super Ubiquinol Coq10.

If you have any questions about the prevention and/or treatment of collateral damage from chemotherapy or radiation scroll down the page, post a question or comment and I will reply ASAP.

To Learn More about CoQ10- click now

Thank you,

David Emerson

Multiple Myeloma Survivor
MM Cancer Coach
Director PeopleBeatingCancer

Coenzyme q10 for prevention of anthracycline–induced cardiotoxicity.

“Preclinical and clinical studies suggest that anthracycline–induced cardiotoxicity can be prevented by administering coenzyme Q10 during cancer chemotherapy. Studies further suggest that coenzyme Q10 does not interfere with the antineoplastic action of anthracyclines and might even enhance their anticancer effects...

Coenzyme Q10, an essential component of the electron transport system and a potent intracellular antioxidant, appears to prevent damage to the mitochondria of the heart, thus preventing the development of anthracycline–induced cardiomyopathy…”

Gene Variant Linked to Childhood Cancer Drug’s Cardio Side Effects

” In Nature Genetics, an international team described a gene variant that dials up the risk of heart problems in children treated with the cancer drug anthracycline…

Some of the patients had developed cardiotoxicity-related symptoms while others did not…

Although available treatments have extended the lives of many children with cancer, drug-related side effects can cause long-term health problems in a subset of these patients. For instance, the team noted, as many as 57 percent of anthracycline-treated children develop asymptomatic cardiac dysfunction, while an estimated 16 percent experience congestive heart failure…

Consequently, there’s ongoing interest in using genetic approaches to dig for factors that mediate the risk of drug-related complications in children treated with anthracycline or other cancer drugs…”

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Nancy P Hardy says 10 months ago

It is probably best not to take Co-Q10 if you are taking Bortezomib (Velcade): https://pubs.rsc.org/en/content/articlelanding/2022/mo/d1mo00106j

David Emerson says 10 months ago

Thanks for your input Nancy-

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Myeloma- CoQ10 Cardiotoxicity

“clinical studies suggest that (the chemotherapy side effect) anthracycline–induced cardiotoxicity can be prevented by administering coenzyme Q10 during cancer chemotherapy

Recommended Reading:

Coenzyme q10 for prevention of anthracycline–induced cardiotoxicity.

Gene Variant Linked to Childhood Cancer Drug’s Cardio Side Effects

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