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Cryotherapy for Early Breast Cancer-Solution to Over Treatment

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Many patients with breast cancer have relatively non-aggressive disease, but are overtreated,” especially older women… “The solution is to have a treatment option that provides a solution with very little morbidity,” 

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My mom was diagnosed with DCIS at the age of 75. Mom underwent a lumpectomy, five years of an aromatase inhibitor (tamoxifen) and whole-breast radiation. Mom developed atrial fibrillation about 7-8 years after her WBR. I’ll never know if the radiation caused heart damage and her A-Fib but I will always suspect that my mom was over-treated for her DCIS.

That was in 2005. Skip ahead to today. As the article linked and excerpted below explains cryotherapy/cryosurgery could be a less invasive DCIS therapy with reduced risks of collateral damage such as heart damage. It’s too early to definitively say if women who are diagnosed with early stage breast cancer will benefit from cryotherapy. But I look forward to the day when women have the choice.

Mom was diagnosed with DCIS in the other breast about six months ago (12/16).

To learn more about DCIS and the evidence-based therapies that can help you prevent its spread into invasive breast cancer, please watch the video below:

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I am a cancer survivor and cancer coach. Have you been diagnosed with early stage breast cancer? What therapy are you considering? Scroll down the page, post a question or comment and I will reply to you ASAP.

Thank you,

David Emerson

  • Cancer Survivor
  • Cancer Coach
  • Director PeopleBeatingCancer

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Cryoablation shows promise in treating low-risk breast cancers

“Cryoablation — the destruction of cancer cells through freezing — shows early indications of effectiveness in treating women with low-risk breast cancers. Researchers said that over the four years of the study, there has only been one case of cancer recurrence out of 180 patients…

As part of the Ice 3 Trial, Dr. Tomkovich and colleagues at 18 centers across the U.S. have been studying cryoablation as a primary treatment for breast cancer without surgical lumpectomy. Starting in 2014, the researchers began performing cryoablation on women ages 60 and over with biopsy-proven, low-risk breast cancer. The patients undergo the procedure and then are followed for recurrence with mammography at six and 12 months and then annually for five years

“Lumpectomy is 90 to 95 percent effective at removing cancer,” Dr. Tomkovich said. “We were going for something close to that, but our preliminary results have been even better. We’re getting the same results at 18 centers around the country.”

Cryosurgery: The Future of Breast Cancer Treatment?

“A recently completed study by the American College of Surgeons Oncology Group (ACOSOG) found promising results in 86 patients with breast cancer treated with cryosurgery, but called for further evaluation...

Dr Holmes is the principal investigator for a new trial — FROST (ClinicalTrials.gov Identifier: NCT01992250).2 The sponsor, Sanarus Technologies, based in Pleasanton, California, makes the cryoablation device, the Visica 2 Treatment System, which will be used at 20 participating US sites. The system is cleared by US Food and Drug Administration (FDA) for the ablation or destruction of both cancerous and benign tumors...

Like the earlier ACOSOG trial, FROST, will not be randomized, but contains 2 study arms. One arm will enroll women ages 70 and older whose breast cancers, by virtue of age, are generally considered indolent enough to avoid follow-up radiation or sentinel node biopsy…

Dr Holmes added that the other arm will be women aged 50 to 69 years who will be required to have follow-up radiation to reduce the risk of recurrence. But lymph node surgery will be optional in the younger cohort, as will chemotherapy, if the nodes show further cancer…

Each participant will receive 5 years of hormonal therapy following cryosurgery for control of systemic disease. Maximum tumor size at time of diagnosis is 1.5 centimeters or less. Each participant will be clinically node negative, estrogen receptor–positive, and HER2-neu negative at enrollment — “excellent candidates” for minimally invasive cryosurgery, according to Dr Holmes…

 

 

 

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