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[…] Curcumin inhibits “inhibits Aβ-induced neuronal damage” […]
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I admit that I don’t understand all the jargon in the studies linked and excerpted below. But I do understand enough of what the studies are saying to write this blog post. In short:
I am a long-term cancer survivor of an incurable cancer called multiple myeloma. I have researched and supplemented with curcumin since 2006. The only real drawback with curcumin supplementation is it’s inability to get into the bloodstream. Several formulations of curcumin have superior bioavailability.
The brand of Curcumin that I take is Life Extension Super Bio Curcumin . The formulation that LEF developed is much more “bio-available” (absorbed into the blood stream) than other brands. This is why I take LE Super Bio Curcumin .
For more information on nutritional supplementation to help manage chronic disease, scroll down the page, post a question or comment and I will reply ASAP.
thank you,
David Emerson
“There is evidence to suggest that the addition of curcumin to cultured neuronal cells decreases brain inflammation and protects against β-amyloid-induced neurotoxicity…
Curcumin may be beneficial in protecting against development or progression of AD if taken over the long term and started before symptoms of AD become apparent.”
“Alzheimer‘s disease (AD) is one of the common neurodegenerative diseases and amyloid-β (Aβ) is thought to be a key molecule contributing to AD pathology…
Recently, curcumin is supposed to be beneficial to AD treatment. This study investigates the inhibitory effects of curcumin on Aβ-induced cell damage and death involving NMDA receptor-mediated intracellular Ca(2+) elevation in human neuroblastoma SH-SY5Y cells. Cells were impaired significantly in Aβ-damaged group compared with the control group, and cell viability was decreased while the released LDH from the cytosol was increased…
Curcumin promotes cell growth and decreases cell impairment induced by Aβ.
These results indicated that curcumin inhibits Aβ-induced neuronal damage and cell death involving the prevention from intracellular Ca(2+) elevation mediated by the NMDA receptor.
[…] Curcumin inhibits “inhibits Aβ-induced neuronal damage” […]
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