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Diet Slows MGUS Progression

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Diet slows MGUS progression? It wasn’t too long ago when pre-MM patients (MGUS, SMM) were told that there were no therapies for MGUS and that there was nothing they could do to treat their blood disorder.

To be honest, I think that this study simply proves what most laypeople know about the impact of nutrition on pre-MM. I think the study below is instructing conventional oncology to get their heads out of the sand…


Listen to Dr. Shah talking about nutrition and MGUS, SMM


Keep in mind that hundreds of studies have already demonstrated the ability of curcumin to kill monoclonal proteins slowing the progression of pre-MM to frank MM.

I am a long-term MM survivor. I decided to not undergo any conventional therapies for my MM after I was told I was end-stage in late 1997. I follow an anti-mm lifestyle through diet, supplementation and lifestyle therapies.

Email me at David.PeopleBeatingCancer@gmail.com if you would like to learn more about how to understand your risk of progression to MM based on your diagnostic info or if you would like to lean more about evidence-based non-conventional therapies shown to reduce the risk of MM.

thank you,

David Emerson

  • MM Survivor
  • MM Cancer Coach
  • Director PeopleBeatingCancer

Study links high-fiber diet to delayed progression of blood cancer

“Researchers at Memorial Sloan Kettering Cancer Center (MSK) have reported results from the first-ever clinical trial demonstrating that a high-fiber, plant-based dietary intervention may delay progression to multiple myeloma, a rare and incurable blood cancer affecting the bone marrow…

The study enrolled 20 participants with a precancerous blood disorder and an elevated body mass index (BMI) at risk of developing multiple . They received 12 weeks of high fiber plant-based meals and 24 weeks of coaching. Two participants with progressing disease prior to the study showed a significant improvement of their disease progression trajectory. Additionally, at one year after enrollment, none of the participants had progressed to multiple myeloma

“This study showcases the power of nutrition—specifically a high fiber plant-based diet—and unlocks a better understanding of how it can lead to improvements in the microbiome and metabolism to build a stronger immune system,” said Dr. Shah. “These findings further support how we as physicians can empower patients, especially those with precancerous conditions, with knowledge on reducing their through dietary changes…”

During the study, participants were encouraged to eat as much as they wanted if it was whole plant-based foods such as fruits, vegetables, nuts, seeds, whole grains, and legumes. With these dietary changes there were significant improvements in quality of life, , gut microbiome health and inflammation.

On average, participants lost eight percent of their body weight after 12 weeks. Following these positive results, Dr. Shah is currently enrolling for a larger, multi-center study with 150 participants called NUTRIVENTION-3

These findings were confirmed in a smoldering myeloma mouse model where 44% of mice fed the high fiber diet did not progress to myeloma compared to the standard diet where all mice progressed to myeloma…”

A High-Fiber Dietary Intervention (NUTRIVENTION) in Precursor Plasma Cell Disorders Improves Biomarkers of Disease and May Delay Progression to Myeloma

“Conclusion- This is the first interventional clinical trial and in vivo study to show that a HFPBD intervention may delay progression from MGUS/SMM to MM. To our knowledge there has been no similar dietary interventional study in hematological cancers or solid tumors. Together our in vivo and clinical data support the beneficial anti-inflammatory role of a HFPBD providing a link between diet, microbiota, and immune modulation to delay disease progression in MGUS/SMM…”

Diet slows MGUS progression Diet slows MGUS progression

 

 

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