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Recently Diagnosed or Relapsed? Stop Looking For a Miracle Cure, and Use Evidence-Based Therapies To Enhance Your Treatment and Prolong Your Remission

Multiple Myeloma an incurable disease, but I have spent the last 25 years in remission using a blend of conventional oncology and evidence-based nutrition, supplementation, and lifestyle therapies from peer-reviewed studies that your oncologist probably hasn't told you about.

Click the orange button to the right to learn more about what you can start doing today.

Enzyme alpha-1-antitrypsin, MM, Allo SCT, Graft-Vs.-Host Disease (GvHD)

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“A natural enzyme derived from human blood plasma showed potential in significantly reducing the effects of graft-vs.-host disease (GvHD), a common and deadly side effect of lifesaving bone marrow transplants for MM.”

When I underwent an autologous stem cell transplant for my multiple myeloma (MM) in 12/95 I did so because allo SCT were too dangerous. Auto SCT’s were safer than allo SCT’s. Graft vs. Host disease (GvHD) is still a serious side effect of allo SCT. As you can see from the article linked and excerpted below, allo transplants have come a long way.

Allogeneic (the stem cells come from a donor) Hematopoietic stem cell transplantation sometimes can actually cure the patient from whatever blood cancer he/she is suffering from. That’s the good news. The bad news is that allo BMT’s result in GvHD in 30%-70% of patients. GvHD can result in relatively minor collateral damage up to death.

Due to the problematic nature of GVHD, anything that has the potential to treat this difficult side effect needs to be explored.

I am both a Multiple Myeloma survivor and MM cancer coach.  My experience as a long-term survivor of this incurable blood cancer has taught me that there is a world of evidence-based, non-conventional therapies that can ease or eliminate the collateral damage caused by conventional toxic therapies.

I work with MM patients to research and identify those therapies that can enhance their treatments while reducing or eliminating their short, long-term and late stage side effects of therapy.

Have you been diagnosed with multiple myeloma? Are you considering a bone marrow transplant? Have you had a BMT and are experiencing GvHD?  Scroll down the page, post a question or comment and I will reply ASAP.

thank you,

David Emerson

  • Multiple Myeloma Survivor
  • MM Cancer Coach
  • Director PeopleBeatingCancer

Recommended Reading:


Hematopoietic stem cell transplantation

Hematopoietic stem cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood.[1][2] It may be autologous (the patient’s own stem cells are used), allogeneic (the stem cells come from a donor) or syngeneic (from an identical twin)…”

Natural Enzyme Provides Potential New Approach for Treating Graft-Vs.-Host Disease

A natural enzyme derived from human blood plasma showed potential in significantly reducing the effects of graft-vs.-host disease, a common and deadly side effect of lifesaving bone marrow transplants…

In this study, which appears in the Proceedings of the National Academy of Sciences, researchers used alpha-1-antitrypsin in mice that received allogeneic bone marrow transplants. The drug significantly reduced mortality from graft-vs.-host disease, compared to control mice who did not receive the drug.

In addition, alpha-1-antitrypsin reduced the number of inflammatory cells called T Effector cells that are known to be present in graft-vs.-host disease. It also increased the number of T-regulatory cells, which immunologists believe play a positive role in immune responses.”

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6 comments
Sibling Cord Blood May Offer Best Chance For Bone Marrow Transplant - PeopleBeatingCancer says 3 years ago

[…] Enzyme alpha-1-antitrypsin May Reduce Graft-Vs.-Host Disease (GvHD) […]

Reply
Stem Cell Transplant for Blood Cancers- What you Need to Know - PeopleBeatingCancer says 3 years ago

[…] Enzyme alpha-1-antitrypsin May Reduce Graft-Vs.-Host Disease (GvHD) […]

Reply
Jean Dugan says 3 years ago

My daughter had bmt 6/6/18. Out in 12 days. Excellent CBC. Early July lv enzymes went up. I complained. No one listened. Now they think GVHD of liver.

Oops. I already wrote you. Sorry.

Can you help me with this? Thanks

Reply
    David Emerson says 3 years ago

    Hi Jean,

    No problem writing me twice. I don’t remember what I said last time but I think that 1) the article you read cites alpha-1-antitrypsin as possibly helping your daughter. You should ask your oncologist. Secondly, there are a number of evidence-based non-toxic therapies that have been shown to reduce or health stem cell transplant side effects. For example, an antioxidant called milk thistle has been shown to help heal the liver- it is possible that your daughter is having problems with her liver due to past chemo and this is why her enzymes increases.

    David Emerson

    Reply
Jean says 3 years ago

My daughter had a BMT 6/6. Elevated liver enzymes now. Doc thinks graft vs host. Wants to give prednesone….argh.

Reply
    David Emerson says 3 years ago

    Hi Jean,

    Your oncologist is prescribing the standard-of-care therapy, prednisone, for your daughter’s elevated liver enzymes. High dose steroids have been shown to boost one’s immune system.

    David Emerson

    Reply
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