Flaxseed oil- Chemotherapy Synergy in Breast Cancer

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Flaxseed Oil did not interfere with Trastuzumab in breast cancer but rather enhanced its tumor-reducing effects and combined Flaxseed Oil and low dose Trastuzumab was as effective as high dose TRAS treatment.

I am both a cancer survivor and cancer coach. I often encourage cancer patients to add integrative therapies to their conventional chemotherapy and radiation. Research has repeatedly shown that the efficacy of chemo can be enhanced with many different integrative therapies. Flaxseed oil is one of those integrative therapies.

Flaxseed oil (FO), according to the study linked below, enhances the efficacy of Trastuzumab (TRAS). In fact, there are a number of evidence-based supplements that work with conventional chemotherapies to both enhance efficacy while reducing toxicity.

To learn more about interactive therapies for breast cancer, scroll down the page, post a question or comment and I will reply ASAP.

Thank you,

David Emerson

  • Cancer Survivor
  • Cancer Coach
  • Director PeopleBeatingCancer

Flaxseed oil-trastuzumab interaction in breast cancer.

“Flaxseed oil (FO), which is rich in n-3 fatty acid, is commonly consumed by breast cancer patients because of its potential anti-cancer effects. Trastuzumab (TRAS) is the primary drug for epidermal growth factor receptor 2 (HER2) positive breast cancer.

We investigated in athymic mice whether combining dietary FO (8%) with TRAS treatment (2.5 or 5mg/kg body weight) can cause better or adverse effect on established human breast tumors overexpressing HER2 (BT-474). Control tumors significantly grew 187%, TRAS2.5 treated tumors did not change, while TRAS5, FO+TRAS2.5 and FO+TRAS5 treated tumors significantly regressed 75%, 89% and 84%, respectively, after 4weeks treatment.

Two weeks after stopping TRAS treatment while continuing on same diet, tumor size in FO+TRAS2.5 group was 87% lower than in TRAS2.5 group and was not different from TRAS5 group with or without FO. Combined TRAS2.5 treatment with FO caused a significantly lower tumor cell proliferation and higher apoptosis compared to TRAS2.5 treatment alone and showed similar effect to TRAS5 treatment with or without FO.

Hence, FO did not interfere with TRAS but rather enhanced its tumor-reducing effects and combined FO and low dose TRAS was as effective as high dose TRAS treatment.”

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