Glioblastoma Multiforme Diagnosis- Conventional, Non-Convention Therapies

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Diagnosis of GBM, Resection, Radiation, Novocure Device, Steroids, Keppra, Temodar, What Else Can We Do?

Hi David-
I hope that you are doing well.  I read some of your information  and the way that you have given time to doing research on cancers. I found you to be very informative. Some family member of mine has glioblastoma multiform stage 4.

Real Brain Tumor New tool may better distinguish brain tumors from ...I dont know what to do. He had a resection then radiation and goes now to UPMC to get a needle on the inner thigh that is four needles once a month. Not sure of what it is called but that and combination of a head device novocure seems to be making him better.  He eats a lot of blueberries . he has lost his taste for many foods. At first he was put on steroids and got fat. At this time its been nine months since his resection. He is now 155 at 5’6 feet tall. He eats less every day. He says that he has totally lost taste for anything that he use to like . Chocolate and sugars which are not good for cancer has left his appetite. The only medication that he is on is Keppra. He use to take temodar but stopped as he could not tolerate the weakness and seizures that he got.

  • Can you tell me what diet I can give him?
  • Will you please tell me about immune therapy.
  • Tell me about new trial studies that he can involve himself with.


Hi Sharick-
Thank you for your kind words. I am sorry to read of your family member with glioblastoma (GBM) stage IV. As you know this is an aggressive cancer. Surgically removing the brain tumor (resection) is a good way of de-bulking the tumor. Excellent start. Further, the novocure device is one of the few FDA approved therapies shown to increase the length of life for GBM patients.
However, as you have probably been told, the likelihood of relapse, the GBM returning, is good. I encourage you to pursue additional therapies to both enhance your family member’s quality of life as well as length of life.
To address your question ” Can you tell me what diet I can give him?” yes, there are nutritional therapies that combine with antioxidant supplementation that studies have shown are cytotoxic (kill) GBM cancer.
As for lack of appetite, this may be a side effect called “cachexia” which is a side effect that is a leading cause of death for cancer patients. Yes, there are therapies to help fight this side effect by increasing the cancer patients appetite.
Keppra is a medication for seizures. It is not curative for GBM patients.
Please learn about antioxidant nutritional supplementation that may enhance the GBM killing ability of Temodar aka Temozoline while REDUCING its toxicity/side effects.
To answer your question “Will you please tell me about immune therapy” there are many vaccines that are being studied and tested for brain cancers. There are too many to talk about in one email. Please register as a member of PeopleBeatingCancerCoaching.org so I can further research this issue for you.
Like wise your question “Tell me about new trial studies that he can involve himself with there are dozens of studies for GBM patients to enlist in. I need to know where you live, where you are able to travel, what therapies you may be interested in, and more.

Sharick, as you can read above, there are issues and therapies that your family member can do, either personally or with an oncologist, that may help him/her manage his/her GBM. I am both a cancer survivor and a cancer coach. In order to spend the time needed to research your situation further, I need you or your family member to become a cancer coaching member.

Thanks and let me know if you have questions.
David Emerson
  • Cancer Survivor
  • Cancer Coach
  • Director PeopleBeatingCancer

Natural Bioactive Compounds: Alternative Approach to the Treatment of Glioblastoma Multiforme

“Glioblastoma multiforme (GBM) is the most frequent, primary malignant brain tumor prevalent in humans. GBM characteristically exhibits aggressive cell proliferation and rapid invasion of normal brain tissue resulting in poor patient prognosis.

The current standard of care of surgical resection followed by radiotherapy and chemotherapy with temozolomide is not very effective. The inefficacy of the chemotherapeutic agents may be attributed to the challenges in drug delivery to the tumor.

Several epidemiological studies have demonstrated the chemopreventive role of natural, dietary compounds in the development and progression of cancer.

Many of these studies have reported the potential of using natural compounds in combination with chemotherapy and radiotherapy as a novel approach for the effective treatment of cancer.

In this paper, we review the role of several natural compounds individually and in combination with chemotherapeutic agents in the treatment of GBM. We also assess the potential of drug delivery approaches such as the Gliadel wafers and role of nanomaterial based drug delivery systems for the effective treatment of GBM…”

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