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Got Androgen Deprivation Therapy? (ADT)-Get Nutritional Supplementation-

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This review summarizes pre-clinical and clinical studies investigating the ability of dietary supplements to alleviate adverse effects arising from Androgen Deprivation Therapy. In particular, we focus on herbal compounds, phytoestrogens, selenium (Se), fatty acids (FA), calcium, and Vitamins D and E

Prostate cancer is the most common cancer among men in western societies. Androgen Deprivation Therapy (ADT) has is a major therapeutic strategy for Prostate Cancer. The challenge is that men who undergo this therapy many experience side effects including hot flashes, cardiotoxicity, metabolic and musculoskeletal alterations.

Image result for image of adt side effects prostate cancer

As the study at the bottom of this blog illuminates omega 3 fatty acids, calcium and vitamin D supplementation can go a long way in managing many of the worst side effects due to ADT

I am a long-term cancer survivor and cancer coach. I have taken omega 3 fatty acids and vitamin D3 for years for several reasons. In short, taking these two evidence-based supplements has helped me remain cancer-free from my “incurable” cancer while I manage my chemo-induced brain, heart and nerve damage.

I take Life Extension Super Omega 3   (1 capsule daily) as well as Life Extension Vitamin D3 (3 x 1000mg daily) as well as other supplements.

Have you been diagnosed with prostate cancer? Are you undergoing ADT? Please scroll down the page, post a question or comment and I will reply to you ASAP.

thanks

David Emerson

  • Cancer Survivor
  • Cancer Coach
  • Director PeopleBeatingCancer

Recommended Reading:


Hormone Treatment for Prostate Cancer Tied to Heart Risks

“A common treatment for prostate cancer may increase the risk for heart disease…

Men who did not have pre-existing cardiovascular disease who underwent A.D.T. had an 81 percent increased relative risk for heart failure compared with men who did not get the drug regimen. They also had slightly increased risks for heart rhythm disorders…

The lead author, Reina Haque, a research scientist at Kaiser Permanente in Pasadena, Calif., said that the results could be particularly important for prostate patients who have risk factors for heart disease. The study, she said, provides “a way to begin a conversation about whether A.D.T. is a treatment you should use…””

Androgen-Deprivation Therapy in Prostate Cancer and Cardiovascular Risk

“There is a substantial amount of data demonstrating that ADT adversely affects traditional cardiovascular risk factors, including serum lipoproteins, insulin sensitivity, and obesity….”

The Use of Dietary Supplements to Alleviate Androgen Deprivation Therapy Side Effects during Prostate Cancer Treatment

“This review summarizes pre-clinical and clinical studies investigating the ability of dietary supplements to alleviate adverse effects arising from ADT. In particular, we focus on herbal compounds, phytoestrogens, selenium (Se), fatty acids (FA), calcium, and Vitamins D and E…

Fatty Acids (FA)

The relative amounts and different types of dietary FA are thought to play critical roles in PCa associated MetS. Total FA intake and the ratio of omega-3 (ω-3) to omega-6 (ω-6) polyunsaturated FA (PUFAs) in the Western diet have increased significantly since the Industrial Revolution []. The effects of ω-3 PUFAs on CV disease, cancer as well as MetS have been investigated extensively…

Calcium and Vitamin D

Osteoporosis is a common and one of the most debilitating side effects of ADT. The most important nutritional factors contributing to osteoporosis include deficiencies in Vitamin D and calcium…

Complications of Androgen Deprivation Therapy in Men With Prostate Cancer

“The standard treatment for men with metastatic prostate cancer is androgen deprivation therapy (ADT). This therapy is associated with a multitude of side effects that can impact quality of life. These include:

  • vasomotor complications (in particular, hot flushes),
  • sexual dysfunction and gynecomastia,
  • osteoporosis,
  • metabolic syndrome, and
  • depression…”

 

 

 

 

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