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Serum Vitamin D3 – Colorectal Cancer

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These results suggest that higher 25OHD levels at surgery may be associated with a better survival rate of patients with colorectal cancer.

Numerous studies and articles posted on PeopleBeatingCancer cite vitamin D3 blood serum levels as both a predictor of cancer survival as well as a non-conventional therapy to manage cancer and the side effects that come with conventional therapies. The study linked and excerpted below suggests that vitamin D3 may be beneficial for colorectal cancer (CC) patients too.

This is another interesting article dealing with vitamin D levels and cancer, in this case, colorectal cancer and the levels of 250HD at the time of surgery.  I was interested in the fact that “serum 250HD levels were measured in 257 patients [and] only 3% had sufficient levels (30 ng/ml and greater).”  I hope much more vitamin D research will be conducted.

A large and growing number of studies point to supplementation as being an essential part of surviving cancer. I know that supplementation has been important to my own long-term survival.
Have you been diagnosed with colorectal cancer? Are you considering surgery? Please consider “prehabilitation” to prepare for your surgery.
thank you,
David Emerson 
  • Cancer Survivor
  • Cancer Coach
  • Director PeopleBeatingCancer

Recommended Reading:

Vitamin D May Help To Prevent CC In Young People

“The number of people affected by young-onset colorectal cancer has been steadily rising over the past few decades, but researchers aren’t currently sure why this is happening. Now a new study published in the journal Gastroenterology has indicated that consuming higher amounts of vitamin D may help to protect against developing colorectal cancer and pre-cancerous polyps in people under 50.

The overall numbers of people being diagnosed with CC are falling, but not in people under 50. Sadly, high-profile deaths of young people like Black Panther star Chadwick Boseman are hitting the news more frequently as awareness grows about the disease in younger people…

“Vitamin D has known activity against CC in laboratory studies,” said Kimmie Ng, MD, MPH, Director of the Young-Onset CC Center at Dana-Farber Cancer Institute in Boston and senior author of the study. “Because vitamin D deficiency has been steadily increasing over the past few years, we wondered whether this could be contributing to the rising rates of CC in young individuals,” added Ng.

Dietary intake of vitamin D from foods such as fish, eggs, milk and mushrooms has reduced in recent years, but no study to-date has investigated the potential link between this and increased incidence of colorectal cancer in young people…

Our results further support that vitamin D may be important in younger adults for health and possibly CC prevention. It is critical to understand the risk factors that are associated with young-onset CC so that we can make informed recommendations about diet and lifestyle, as well as identify high risk individuals to target for earlier screening,” said Ng…”

Serum vitamin D levels and survival of patients with colorectal cancer: Post-hoc analysis of a prospective cohort study

BACKGROUND: Recently, serum 25-hydroxyvitamin D (25OHD) levels were shown to be associated with the survival of patients with CC. However, 25OHD levels were measured a median of 6 years before diagnosis or were predicted levels. In this study, we directly measured serum 25OHD levels at surgery and examined the association with survival among patients with CC.

RESULTS: Serum 25OHD levels were measured in 257 patients. Only 3% had sufficient levels (30 ng/ml and greater).

Conclusions These results suggest that higher 25OHD levels at surgery may be associated with a better survival rate of patients with CC.

New study shows high vitamin D levels increase survival of patients with metastatic colorectal cancer

“According to a new study led by researchers at Dana-Farber Cancer Institute, clinical trial patients with metastatic CC who had high levels of vitamin D in their bloodstream prior to treatment with chemotherapy and targeted drugs, survived longer, on average, than patients with lower levels of the vitamin…

The research, based on data from more than 1,000 patients with metastatic CC who enrolled in a phase 3 clinical trial of chemotherapy plus biologic therapies, adds to vitamin D’s already impressive luster as a potential cancer-inhibiting agent. In the study, patients with the highest blood levels of vitamin D survived for a median period of 32.6 months, compared to 24.5 months for those with the lowest levels…”

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