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Is “Plasma Cell Dyscrasia” a Diagnosis of MGUS, SMM or MM?
“Plasma cell dyscrasias (MGUS, SMM, MM) are a heterogeneous group of disorders caused by the monoclonal proliferation of lymphoplasmacytic cells in the bone marrow. Multiple myeloma is the most serious and prevalent plasma cell dyscrasia..”
David, my oncologist says I have plasma cell dyscrasia. As far as I can find out that is the same as MGUS (monoclonal gammopathy of undetermined significance). Not full-blown multiple myeloma (MM).
What dose of CBD oil would you suggest and what other supplements? Can you give me a list with doses? Thank you so much for caring and for your help. – Ned
Dear Ned,
Plasma cell dyscrasia is the general family of blood disorders for MM, MGUS, SMM. The next step is for you to determine your degree or amount of mm cells are in your blood- how advanced your PCD is. If your m-spike or monoclonal protein is under 3.0, you have pre-MM, MGUS or SMM. The pre-MM cancer coaching program contains evidenced-based, non-toxic therapies to reduce your risk of a full-blown MM diagnosis.
CBD oil has been shown to ba antiangiogenic and is integrative or synergizes with Velcade (a MM chemotherapy regimen). There has not been enough research done as to whether CBD actually is cytotoxic (kills) MM. To answer your question about CBD dosing, first find a strain of CBD oil with a high percentage of cannbinoids. Most MMers think a small percentage of THC is most efficatious for killing MM but as I said, it is still an open question as to whether or not CBD kills MM.
Once you find a CBD oil with a high percentage of cannabinoids ( I will link a blog post with the names of several high percentage strains below), when you are ready to take your first dose (most people recommend dosing before bed in case you feel tired) simply put several drops under your tongue.
The idea is to start slowly and to increase your daily dose in an effort to see how you respond.
My point is that while research into CBD oil has concluded that CBD can reduce pain, reduce anxiety, build bones, others, research has not confirmed efficacy of MM cytotoxicity. My advice to you is to consider the evidence-based, non-toxic therapies in the Pre-MM CC program. For example, curcumin has been shown to be cytotoxic to MM.
If you have pre-myeloma, either MGUS or SMM, your goal is to prevent a diagnosis of full-blown or frank multiple myeloma. Hopefully, for the rest of your life.
Let me know if you have any questions.
David Emerson
- MM Survivor
- MM Cancer Coach
- Director PeopleBeatingCancer
Recommended Reading:
- Cancer Coaching- What is the Best Brand of C-B-D oil for Myeloma?
- Myeloma Bone Pain- Cannabinoids, Opioids, Bone Health Therapies?
- A Long-term Multiple Myeloma Survivor’s Diet, Nutrition Plan-
5 High Cannabinoid Percentage C-B-D Oil Strains for Multiple Myeloma
“I don’t like the feeling of being high. There, I said it. But I am a long-term multiple myeloma (MM) survivor and MM cancer coach so I want to learn all I can about the health benefits of C-B-D oil. Myeloma survivors and caregivers frequently contact me asking about C-B-D oil and its possible efficacy as a therapy for them. Unfortunately, I can make only vague statements related to the ideas outlined below.
Studies of cannabinoids, while still somewhat thin, indicate that
- C-B-D oil can synergize with certain multiple myeloma chemotherapy regimens,
- C-B-D can manage pain from multiple myeloma and
- cannabinoids may even be cytotoxic to MM itself.
I follow an anti-MM diet, an anti-MM nutritional supplementation regimen and I may also be able to supplement with a non-psychotropic, high cannabinoid C-B-D oil.
But here’s the thing. Many C-B-D oils have a very low percentage of cannabinoids IN them. Since it is cannabinoids that are the medicine aka the good stuff, then low percentages of the good stuff is not what I want. I want as high a percentage of cannabinoids IN the C-B-D oil I buy as possible.
Another fly in the ointment is that C-B-D strains are all over the place, from the perspective of availability. I want to be able to walk into a medical marijuana dispensary and ask for the highest cannabinoid percentage C-B-D oil possible.”