You aska great question. Perhaps the ultimate question for newly diagnosed multiple myeloma patients. As you can imagine, the answer is complicated. Let me address your question by starting at the beginning.
Pre-Multiple Myeloma- MGUS, SMM-
The diagnostic information about this group would be, for example, serum proteins of less than 10%, no bone/kidney damage, an m-apike of less than 1.
Yes, it is possible to remain pre-MM solely with evidence-based, non-toxic, non-conventional therapies. I say this because I have worked with several MGUS patients who
have lived with a low m-spike for years. Yes, their m-spike may bounce up and down a bit. The patients I am thinking of are older people who know that toxic therapy will damage their lives. It is possible that pre-MM in the senior citizen grows slowly as well.
Also keep in mind that MGUS proceeds to MM at a rate of about 1-2% a year. It is theorized that MGUS patients can live for decades without knowing that they have MGUS. SMM progresses to MM at a rate of about 10% a year. Margaret of Margaret’s Corner
has lived with SMM for more than 15 years (I think).
This group- MGUS or SMM may be less interested spending a lot of time and/or money on non-conventional therapies. After all, they have not been diagnosed with cancer.
So, for example, while intravenous vitamin C has been shown to fight MM well, the user needs to undergo 3-4 infusions a week for several weeks for this therapy to be effective. This much therapy may be expensive and time consuming.
Early stage multiple myeloma- stage 1 but just barely.
By “just barely” I mean just over the line from pre-MM to full-blown MM but just barely. A key separation of pre and full blown MM is the amount of organ damage. If the newly diagnosed MM patient has no organ damage, he/she has just a small amount of MM in their blood and therefore can manage it more easily.
This group has been diagnosed with cancer and therefore may make more effort at undergoing non-toxic therapies. Intravenous vitamin C, anti-angiogenic nutrition, supplementation, daily exercise, daily whole-body hyperthermia/detox, homeopathic remedies, acupuncture- there is a lot of health stuff out there.
Full-blown MM stage II or III-
I don’t believe that this group of MM survivors can fight/cure/manage their MM solely with non-toxic therapies. Their bodies have sustained too much damage to be able to heal both their bodies and their bone marrow.
Keep in mind that after 4 years of aggressive toxic therapies, remission, relapse, remission, relapse- I was diagnosed at end-stage MM, was walking around with considerable bone involvement, pain, etc. I managed to undergo a non-toxic therapy (evidence-based but not for MM), and achieve complete remission where I have remained since.
I discuss that therapy in the non-conventional therapies guide- Antineoplaston Therapy- The Burzynski Research Institute. There are two distinct components to this. First, achieving complete remission from end-stage MM. I credit ANP exclusively for this.
I do not credit ANP for preventing a relapse of my MM or a treatment-related secondary cancer. After all of the chemotherapy and radiation I underwent from ’94-’97, the odds of a secondary cancer are overwhelming. I credit the MM CC program for preventing that nasty side effect.
The real issue, for the majority of MM patients and survivors, is a combination of toxic and non-toxic therapies. The reason why I posted the blog about “What is MM…”
is because most MM patients have to contend with the MM itself, symptoms, and side effects. I believe that each patient must balance all three in order to live the best life possible.
Let me know if you have any questions. I am going to post your question and my reply to Beating Myeloma- anonymously of course.
“High-dose chemotherapies to treat multiple myeloma (MM) can be life-threatening due to toxicities to normal cells and there is a need to target only tumor cells and/or lower standard drug dosage without losing efficacy.
We show that pharmacologically-dosed ascorbic acid (PAA), in the presence of iron, leads to the formation of highly reactive oxygen species (ROS) resulting in cell death.
PAA selectively kills CD138+MM tumor cells derived from MM and smoldering MM (SMM) but not from monoclonal gammopathy undetermined significance (MGUS) patients.
PAA alone or in combination with melphalan inhibits tumor formation in MM xenograft mice. This study shows PAA efficacy on primary cancer cells and cell lines in vitro and in vivo…”
“Example No. 1: David Emerson was 34 when diagnosed with multiple myeloma in February of 1994. He underwent induction therapy of 5 rounds of VAD (Vincristine, Adriamycin, Dexamethasone), 2 rounds of Cytoxan and an autologus bone marrow transplant, all in 1995. In October of ’96 he relapsed, underwent local palliative radiation to reduce the pain in his bones, relapsed again in September ’97, and was told “nothing more can be done for you…”