Low-dose Maintenance Therapy Increases Multiple Myeloma Overall Survival

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Combine Conventional (Lenalidomide) with Evidence-based Non-Conventional Low-dose Maintenance Therapy to Increase OS While Decreasing Toxic Damage 

The issue in the study linked and excerpted below is not if lenalidomide (revlimid) is the reason for increased overall survival in multiple myeloma (MM), the issue is whether or not low-dose maintenance therapy is the reason for increases in overall survival in multiple myeloma.

What I mean by the above statement is that my research and personal myeloma experience is that hitting MM daily is the reason why I have remained in complete remission from my MM since my complete remission in 4/99.


There are three known facts about revlimid:

  1. revlimid is antiangiogenic
  2. revlimid causes secondary cancers
  3. low-dose maintenance therapy is “metronomic therapy”

Evidence-based anti-MM therapies such as curcumin, whole-body hyperthermia and exercise are also forms of metronomic therapy that can work synergistically with revlimid and do not cause secondary cancers. The Multiple Myeloma Cancer Coaching program discussed in the webinar to the right outlines dozens of evidence-based, non-toxic therapies that can work integratively and synergistically with revlimid.

I am both a myeloma survivor and myeloma cancer coach. Please scroll down the page and post a question or comment and I will reply to you ASAP.

Thank you,

David Emerson

  • Myeloma Survivor
  • Myeloma Cancer Coach
  • Director PeopleBeatingCancer

Lenalidomide extends myeloma survival after stem cell transplantation

“Maintenance therapy with lenalidomide following autologous hematopoietic stem cell transplantation reduced mortality rates by 25% compared with placebo or observation among patients with newly diagnosed multiple myeloma, according to results of a meta-analysis…

Patients treated with lenalidomide demonstrated improved Progression Free Survival compared with those who received placebo or observation…


David Emerson is a 23 year Multiple Myeloma survivor. He started PeopleBeatingCancer.org as a non-profit in 2004 to help cancer survivors and caregivers navigate the vast world of cancer issues by providing evidence-based information on the most pressing cancer issues. Since 2004, David has impacted over 600,000 people through this website. He is in the process of developing cancer-specific coaching program, and also does one-on-one coaching via phone or email. Thank you for visiting!

Posted in Multiple Myeloma, non-conventional therapies Tagged with:
4 comments on “Low-dose Maintenance Therapy Increases Multiple Myeloma Overall Survival
  1. JoAnn M. Stiles Cramer says:

    Found out I had MM in May, my doctor said I would have had 2 weeks to live if it was nit detected! My kidneys were clogged, and fell at the hospital and broke my arm( which was a blessing in disguise) spent 9 days and got cancer treatments and fluids immediately! Today my doctor said I’m doing so well my blood work doesn’t even look like I have cancer! They are so amazed at how the chemo, Revlimid and regular MM treatment is working on me! I’m really blessed!! My question is can the cannibis oil help with the cure??Will it interfere with my treatment?

    • David says:

      Hi JoAnn-

      I am sorry to read of your MM diagnosis though happy to read that you are now in remission. You are correct on two counts. Yes, conventional MM chemotherapy drugs such as revlimid will eventually stop working (MM eventually becomes resistant…). And yes, CBD oil has been shown to enhance the efficacy of revlimid (aka bortezomib). I cannot tell you that CBD cures MMers but it will synergize with chemo.

      I encourage you to add evidence-based but non-toxic therapies such as CBD oil, anti-MM nutrition, supplementation, bone health and other therapies to your regimen.

      Let me know if you have any questions.

      Hang in there,

      David Emerson

  2. Chris says:

    Hi David-
    I was diagnosed with stage1 MM in Sept 2016. Since then, I have gone thru autogolous SCT (Jan 2017), melphalan treatment prior to SCT, two cycles of RVD post SCT, and am currently on Revlimid maintance. I didn’t find Your site until recently and I have been intrigued. My most recent M spike results went from unquantifiable to sub 0.5. While that is still very low, I would like to do my part in some form of integrative therapies. Not knowing where to go or who to trust with this, I landed here and am writing you now.
    The CBD oil, curcumin and Omega-3 therapies seem to make the most sense. However, any suggestions you may have would be greatly appreciated.

    • David says:

      Hi Chris-

      I will send a guide about integrative MM therapies to you via your email address. This info will give you an understanding of “doing your part” in enhancing the anti-MM action of revlimid.

      You are correct. Your m-spike is still quite low which is excellent but the goal is to keep it there (low) for years if no decades. CBD oil is also mentioned as an integrative therapy but the efficacy of CBD oil depends on the state in which you live.

      Read over the integrative therapies guide and let me know if you have any questions.

      Hang in there,

      David Emerson

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