As a long term survivor of an incurable cancer, Multiple Myeloma, it became clear to me many years ago that many cancer patients need to venture beyond conventional oncology in order to heal themselves. Pancreatic cancer patients face the same challenges as MM patients face. Low-Dose Naltrexone (LDN) is one such therapy.
Whether you would like to both enhance the efficacy of conventional oncologic chemotherapy or reduce the toxicity of a conventional therapy, the important thing is that there are evidence-based integrative therapies.
While Low-Dose Naltrexone (LDN) is controversial as a cancer therapy, it is a therapy that needs to be learned about for those cancer patients who want to look beyond conventional cancer care. LDN is one of many evidence-based non-conventional cancer therapies. Further, I have remained in complete remission from my incurable cancer with the help of evidence-based, non-toxic therapies such as nutrition, supplementation, bone health, detoxification and mind-body therapies. Again, all supported by research.
“A panel of researchers and clinicians was convened by the National Cancer Institute (NCI) on March 19, 2012 for presentations and a roundtable discussion about “The State of the Science of Alpha-Lipoic Acid plus Low-Dose Naltrexone for the Treatment of Cancer.” The meeting was hosted by the NCI Office of Cancer Complementary and Alternative Medicine (OCCAM) and the Cancer Therapy Evaluation Program (CTEP), both part of the NCI Division of Cancer Treatment and Diagnosis (DCTD)…”
“The authors, in a previous article, described the long-term survival of a man with pancreatic cancer and metastases to the liver, treated with intravenous alpha-lipoic acid and oral low-dose naltrexone (ALA/N) without any adverse effects. He is alive and well 78 months after initial presentation. Three additional pancreatic cancer case studies are presented in this article. At the time of this writing, the first patient, GB, is alive and well 39 months after presenting with adenocarcinoma of the pancreas with metastases to the liver. The second patient, JK, who presented to the clinic with the same diagnosis was treated with the ALA/N protocol and after 5 months of therapy, PET scan demonstrated no evidence of disease. The third patient, RC, in addition to his pancreatic cancer with liver and retroperitoneal metastases, has a history of B-cell lymphoma and prostate adenocarcinoma. After 4 months of the ALA/N protocol his PET scan demonstrated no signs of cancer…”
“Researchers at The Pennsylvania State University College of Medicine, Hershey, Pennsylvania have discovered the mechanism by which a low dose of the opioid antagonist naltrexone (LDN), an agent used clinically (off-label) to treat cancer and autoimmune diseases, exerts a profound inhibitory effect on cell proliferation…”
“LDN combined with cisplatin alleviated the toxicity (e.g. weight loss) associated with cisplatin. LDN treatment upregulated the expression of the opioid growth factor (OGF, chemical term ([Met(5)]-enkephalin) and its receptor, OGFr. Previous tissue culture studies have reported that OGF is the only opioid peptide with antiproliferative activity on ovarian cancer cells, with OGF action mediated by OGFr. Thus, the common denominator of intermittent opioid receptor blockade by short-term NTX or LDN on ovarian cancer proliferation and tumorigenesis recorded herein appears to be related to the OGF-OGFr axis. These preclinical data may offer a non-toxic and efficacious pathway-related treatment that can benefit patients with ovarian cancer.”