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MGUS- Whole-Body Hyperthermia, Sauna?

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“As hyperthermia is nonmyelosuppressive and can potentiate the tumoricidal effects of radiation, chemotherapy, and immunotherapy, its use as part of a multimodality treatment approach..”

I have just been diagnosed with MGUS (monoclonal gammopathy of undermined significance) from my Kappa Light Chain, Free, Serum reading of 23.8 (range 3.3-19.4).

I was wondering what  your opinion on sauna use being helpful to possibly prevent the onset of MM? 

I have the same question pertaining to sitting in a hot tub (spa).   Congratulations on being in submission for so many years, especially in light of what the medical literature states as the 5 year survival rate.
Hi Rich, 
I am sorry to read of your diagnosis of monoclonal gammopathy of undermined significance (MGUS). I want to make sure I understand what you are saying. 
You are saying that your Kappa Free Light chain is 23.8. And the normal range for a Kappa Free Light Chain test is 3.3-19.4? See the linked info below. 
While a diagnosis of MGUS is difficult for many reasons, I tell pre-MM patients that they are in the pre-cancer sweet spot. By this I mean that they do not have cancer (MGUS is considered to be a blood disorder…) but their risk of a multiple myeloma diagnosis is increased. 
A diagnostic marker of a kappa FLC of 23.8, while above the normal range, is still quite low. Yes, your FLC Kappa is high and yes, a diagnosis of MGUS increases your risk of MM by an estimated 1% annually, but there are many evidence-based, non-toxic therapies shown to reduce your risk of MM. 
This is why I call this diagnosis the cancer sweet spot. You have an incentive to undergo anti-MM nutrition, supplementation, lifestyle therapies such as frequent, moderate exercise, whole body hyperthermia, etc. All shown by research to reduce your risk of MM. But you do not have cancer currently and you may never have cancer. 
Specifically to address your question- I was wondering what  your opinion on sauna use being helpful to possibly prevent MGUS from the onset of MM? 
Two issues. First, whole body hyperthermia aka sauna, has been shown to sweat out heavy metals (see the article below). Heavy metals detox. can reduce your risk of MM. 
Secondly, increasing your internal body temperature, according to the study linked below, has been shown to be anti-neoplastic. This is a fancy word meaning internal higher body temps can kill cancer. MM/MGUS cells have been shown to be sensitive to heat. 
Regarding your question about a hot tube, my interpretation of the studies below are that the key issue is increasing a person’s internal body temperature. Whenever I have been in a hot tube, I sweat. So I would think that my internal temperature increases. 
  • Do you know what your m-spike is?
  • Have you had a bone marrow biopsy?
  • Do you have any symptoms such as bone pain or nerve tingling?
Just curious. 
Let me know if you have any other questions. 
David Emerson 
  • MM Survivor
  • MM Cancer Coach
  • Director PeopleBeatingCancer 

Recommended Reading

Blood, urine, and sweat (BUS) study: monitoring and elimination of bioaccumulated toxic elements

 Toxic elements were found to differing degrees in each of blood, urine, and sweat. Serum levels for most metals and metalloids were comparable with those found in other studies in the scientific literature. Many toxic elements appeared to be preferentially excreted through sweat. Presumably stored in tissues, some toxic elements readily identified in the perspiration of some participants were not found in their serum. Induced sweating appears to be a potential method for elimination of many toxic elements from the human body…

Whole body hyperthermia in the treatment of neoplastic disease (MGUS)

“As hyperthermia is nonmyelosuppressive and can potentiate the tumoricidal effects of radiation, chemotherapy, and immunotherapy, its use as part of a multimodality treatment approach is attractive. Three forms of hyperthermia have been developed for clinical application: local, regional, and whole body. As WBH addresses the issue of cancer as a systemic disease, it has perhaps the greatest potential for curative success when used as an adjunct to other therapeutic modalities…”



This test measures the blood levels of the different antibodies (also called immunoglobulins). There are several different types of antibodies in the blood: IgA, IgD, IgE, IgG, and IgM. Each type of antibody fights a different type of infection. The levels of these immunoglobulins are measured to see if any are abnormally high or low. In multiple myeloma, one type of immunoglobulin has overgrowth that crowds out the other types of immunoglobulins, which is why you may be susceptible to certain kinds of infections, like pneumonia. The electrophoresis tests will identify the type of immunoglobulin you have (such as IgG Kappa, IgA Lambda, etc.) …

Plasma cells have heavy and light chains attached together (a “bound” chain). When they detach, you can have too many “free” light chains (or unattached chains) in your blood. This blood test is more accurate than the SERUM FREE LIGHT CHAINS test as the kidneys’ job is to keep protein.


normal range of 3.3-19.40

Leave a Comment:

Karen Weir says 7 months ago

I’m looking at my Free Kappa Light Chain lab & the normal range is listed as: 0.33- 1.94mg/dl
–k. weir

    David Emerson says 7 months ago

    Hi Karen-

    You are correct, the normal range for the kappa reading of your freelight chain assay is .33-1.94. Do you have a question?

    David Emerson

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