Diagnosed with SMM, SPB, or MGUS?

Learn how you can stall the development of full-blown Multiple Myeloma with evidence-based nutritional and supplementation therapies.

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Pre-myeloma, MGUS and Fracture Risk-

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Monoclonal Gammopathy of Undetermined Significancer (MGUS) is a blood disorder, not cancer with a higher-risk of bone damage/fractures-

While conventional oncology considers all forms of pre-Myeloma to be “asymptomatic” as the studies linked and excerpted below explain, many MGUS patients experience symptoms such as bone pain, nerve pain and fractures.

Click the illustration below:

MGUS png Mind Map

MGUS at a glance-

My name is David Emerson. I am a long-term myeloma survivor and multiple myeloma cancer coach. I am writing about MGUS for two main reasons. First, because people who are diagnosed with MGUS are often told to “watch and wait.” And second,  22 plus years surviving multiple myeloma has taught me that there are many evidence-based, non-toxic therapies that MGUS/SMM/MM patients can pursue on their own.

To learn more about how to alleviate bone pain, along with other evidence-based therapies that can help you prevent the development of a Multiple Myeloma diagnosis, please watch the short video below:


Have you been diagnosed with MGUS or some other form of pre-MM? Are you experiencing bone pain? Scroll down the page, post a comment or a question and I will reply to you ASAP.

Consider MGUS Therapies such as:

  1. non-toxic, cytotoxic/apoptotic supplements,
  2. foods that starve growing blood blood vessels
  3. evidence-based mind-body therapies,
  4. detoxification therapies,
  5. Non-conventional bone health therapies

Thank you,

David Emerson

  • MM Survivor
  • MM Cancer Coach
  • Director PeopleBeatingCancer

Recommended Reading:

Fracture risk in monoclonal gammopathy of undetermined significance

“There was a 2.7-fold increase in the risk of axial fractures but no increase in limb fractures…

Altogether, 200 patients experienced 385 fractures. Compared with expected rates in the community, statistically significant increases were seen for fractures at most axial sites, for example, vertebrae

In a multivariate analysis, the independent predictors of any subsequent fracture were

  • age per 10-year increase,
  •  corticosteroid use;
  • greater weight at diagnosis,
  • and IgG monoclonal protein were protective.

Baseline monoclonal protein level, a determinant of myeloma progression, did not predict fracture risk.

Less strength and more fractures for MGUS bones

“In this issue of Blood, Farr et al showed that patients with monoclonal gammopathy of undetermined significance (MGUS) have increased cortical bone porosity and reduced bone strength,1 conditions that can lead to the increased fracture risk, which has been reported in MGUS patients…

The International Myeloma Working Group (IMWG) also suggests bisphosphonates in all MGUS patients with proven osteopenia or osteoporosis.9 Indeed, bisphosphonates increase bone strength through decreasing bone turnover…”

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