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Multiple Myeloma an incurable disease, but I have spent the last 25 years in remission using a blend of conventional oncology and evidence-based nutrition, supplementation, and lifestyle therapies from peer-reviewed studies that your oncologist probably hasn't told you about.

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Multiple Myeloma Diagnosis- “My dad- 70, SBP, now full blown MM?

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Seems like my dad’s multiple myeloma has become active again. I Wanna know best treatment options from your experience and research

My dad had solitary plasmacytoma in November 2015 in his  T8-T10 in spinal cord. He underwent surgery for removal of that tumor. He had 8% multiple myeloma cells in the bone marrow biopsy. No other symptoms other than spinal cord compression. My dad has received radiation at that time. No other treatment was given. 

Further:
  • My dad is 70 and general overall health is very good.
  • he exercises regularly
  • nutrition is very good
But lately he has been feeling weak and unable to continue with his exercise.
What are your thoughts? What treatment options are there?
Ken

 Hi Ken-

My thinking is that your dad’s single plasmacytoma (pre-myeloma not full blown MM) has become full blown MM. This is perfectly normal. In fact, I too had a single plasmacytoma that eventually became frank MM. My guess is that your dad’s MM is still early based on his SBP and BMB results.
Your first step should be to see an oncologist. He/she will confirm whether or now your dad’s diagnosis of pre-MM has become frank MM. My guess that your dad is feeling weak because of his MM causing anemia. Again, your oncologist should confirm this.
Depending on the degree and type of MM (IgG and IgA are most common…) , your oncologist will recommend “induction” therapy. Common chemo cocktail would be RVd (revlimid, velcade, dex) or some other “singlet” or “doublet.”
The goal of this therapy will be to put your dad’s MM into remission. Remission or reducing the level of MM in your dad should help him feel better.
Since your dad is 70 I don’t think your oncologist will push an autologous stem cell transplant. An ASCT is aggressive, high dose chemotherapy- lots of toxicity and difficult for older patients to manage.
Keep in mind that curcumin is notoriously difficult for the body to absorb. Please scroll down the page to learn about the most bioavailable forms of curcumin.
It is probable that your dad’s oncologist will encourage more chemotherapy than I would. I believe in the philosophy that “less is more” in MM therapy when it comes to toxicity.
If you would like to communicate with me about your dad’s progress I will need you to get specifics for at least the items below-
  1.   get your dad’s monoclonal or m-spike- we will compare his before and after his chemo cocktail
  2.   get your dad’s blood work- often called his “complete blood count” or CBC. Red blood cells, (anemia) creatinine (kidney function) others, we can keep an eye on.
  3.   Your dad’s stage and therapy plan- your dad’s oncologist should give you this information.

Please watch the video below to learn more about the evidence-based, integrative therapies to combat treatment side effects and enhance your chemotherapy.

Let me know if you have any questions.
Hang in there,
David Emerson
  • Myeloma Survivor
  • Myeloma Cancer Coach
  • Director PeopleBeatingCancer 

Recommended Reading:


The Most BioAvailable Curcumin Formulas

“Based on a review of these studies, it is evident that better bioavailability of formulated curcumin (CU) products is mostly attributed to improved solubility, stability, and possibly low first-pass metabolism”

A search of the Pubmed database for the word curcumin yields 601 studies spaning health topics from multiple myeloma and colorectal cancer, to chemotherapies that synergizes with CU, to Alzheimer’s Disease, arthritis and more. Based on years of reading studies and personal accounts, I think it is safe to say that CU supplementation is safe and relatively inexpensive.

 

I have read about myeloma patients taking daily doses of CU from 400 milligrams to 8 grams (1000 milligrams = 1 gram). By almost any measure, CU is a safe, inexpensive wonder drug.

The only challenge is that CU is famously difficult to absorb in the body. In other words, a person has to mix curcumin with some sort of fat (coconut oil, chocolate, etc.) or take a brand of curcumin capsule that is already formulated to be more “bioavailable” in order to derive the full benefit of CU.

The study linked and exerpted below reviews different formulations of CU. The study itself lists the three most bioavailable formulation/brand of CU and I’ve added an excerpt from a further review from Consumerlab.com that lists four additional bioavailable brands of CU.


Recommended Reading:


Curcumin

CU is a bright yellow chemical produced by some plants. It is the principal curcuminoid of turmeric (Curcuma longa), a member of the ginger family, Zingiberaceae. It is sold as an herbal supplement, cosmetics ingredient, food flavoring, and food coloring.[1]

Bioavailable curcumin formulations: A review of pharmacokinetic studies in healthy volunteers.

“Curcumin is a widely studied natural compound which has shown tremendous in vitro therapeutic potential. Despite that, the clinical efficacy of the native CU is weak due to its low bioavailability and high metabolism in the gastrointestinal tract. During the last decade, researchers have come up with different formulations with a focus on improving the bioavailability of curcumin. As a result, a significant number of bioavailable curcumin-based formulations were introduced with the varying range of enhanced bioavailability.

The purpose of this review is to collate the published clinical studies of CU products with improved bioavailability over conventional (unformulated) CU. Based on the literature search, 11 curcumin formulations with available human bioavailability and pharmacokinetics data were included in this review. Further, the data on clinical study design, analytical method, pharmacokinetic parameters and other relevant details of each formulation were extracted.

Based on a review of these studies, it is evident that better bioavailability of formulated curcumin products is mostly attributed to improved solubility, stability, and possibly low first-pass metabolism. The review hopes to provide a quick reference guide for anyone looking information on these bioavailable curcumin formulations.

Based on the published reports,

exhibited over 100-fold higher bioavailability relative to reference unformulated CU. Suggested mechanisms accounting for improved bioavailability of the formulations and details on the bioanalysis methods are also discussed.”

According to Consumerlab.com:

“Novasol has the highest bioavailability (185 x compared to unforumulated CU), followed by Curcuwin (136 x), Longvida (100 x), Meriva (48 x), BCM-95 (27 x), Curcumin C3 Complex + Bioperene (20 x), and then Theracumin (16 x).”

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4 comments
Multiple Myeloma Treatments- Long-term Stabilization with Curcumin - PeopleBeatingCancer says a couple of years ago

[…] Cancer Coach-“My dad- 70, SBP, now multiple myeloma? […]

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Myeloma Cancer Coaching- Research of Long-term Stabilization with Curcumin - PeopleBeatingCancer says 3 years ago

[…] Cancer Coach-“My dad- 70, SBP, now multiple myeloma? […]

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Denise says 4 years ago

I have so many questions .. dad was just diagnosed with this where did it come from ? What’s it all about ?is it a major cancer ? Can he get rid of it for good? What is more severe this cancer or Parkinson’s

Reply
    David Emerson says 4 years ago

    Hi Denise-

    I am going to assume that your dad has been diagnosed with multiple myeloma. I can answer your questions as far as the research goes.

    1) no way to determine “where did it come from?” The best research can do is say that certain industries have an increased risk of MM- commercial printing and farming.

    2) “Is it a major cancer?” While MM is considered to be incurable by conventional oncology, MM is very treatable. There is a long and growing list of both conventional (FDA approved) and evidenced based non-conventional therapies. I know of many MMers who have lived with their cancer for more than 10 years. I was first diagnosed with MM in 1994.

    3) As for the severity of MM compared to Parkinson’s, that all depends on your dad’s stage at diagnosis, symptoms and his therapy plan. While the average prognosis for newly diagnosed MM patients is 3-5 years, much of your dad’s prognosis depends on many variables.

    If you can give me more info about your dad I can provide more info. For example, is your dad experiencing any symptoms such as bone damage, fatigue (exhaustion) or kidney issues? Do you know your dad’s stage or blood markers?

    I encourage you to combine the best of both conventional and non-conventional MM therapies.

    Let me know if you have more info.

    Hang in there,

    David Emerson

    Reply
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