Multiple Myeloma an incurable disease, but I have spent the last 25 years in remission using a blend of conventional oncology and evidence-based nutrition, supplementation, and lifestyle therapies from peer-reviewed studies that your oncologist probably hasn't told you about.
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It is in the best interest of multiple myeloma (MM) patients and survivors to consider both conventional and non-conventional therapies to manage their MM. Especially if that multiple myeloma therapy is tasty and will promote heart health and brain health.
One of the most common questions I receive and read in online MM groups is about nutrition, foods, etc. and the newly diagnosed MM. While I am the first MM survivor to go on record as saying that nutrition is not a silver bullet cure for MM, I will say that there are many studies that cite a specific food or type of food that can kill monoclonal proteins (mm cells) or support a certain condition.
The challenge faced by the newly diagnosed MM patient is tha there are different foods for different purposes.
I am both a MM survivor and MM cancer coach. Are you looking for nutritional anti-MM therapies? I talk about fruits, veggies, smoothies, nutraceuticals but none of these anti-cancer therapies are as easy to include in your diet as extra-virgin olive oil.
I don’t envision a MM patient or survivor relying solely on olive oil supplementation to cure his/her cancer. However I do envision cancer patients altering their daily diets to include olive oil, dark chocolate, and organic fruits and veggies.
For more information about non-conventional multiple myeloma therapy such as nutrition or supplementation, scroll down the page, post a question or a comment and I will reply to you ASAP.
“Here we report that this natural compound has a remarkable in vitro activity by inhibiting MIP-1 α expression and secretion in Multiple Myeloma cells. In addition, we also demonstrated that oleocanthal inhibits MM cells proliferation by inducing the activation of apoptosis mechanisms and by down-regulating ERK1/2 and AKT signal transduction pathways. This in vitro study suggests a therapeutic potential of oleocanthal in treating multiple myeloma…”
Our results indicate that oleacein, the most abundant EVOO secoiridoid, elicits significant anti-tumor activity by promoting cell cycle arrest and apoptosis, either as a single agent or in combination with the proteasome inhibitor carfilzomib. Moreover, our data highlight an epigenetic impact of oleacein in MM, as demonstrated by the impairment of the MM acetylome, likely via Sp1-dependent transcriptional inhibition of HDACs. Altogether, these findings provide the molecular rationale for potential epi-therapeutic anti-MM strategies based on natural agents…
HDAC inhibitors (HDACi) are part of the therapeutic armamentarium against MM, and clinical studies have shown promising therapeutic activity of pan- or selective-HDACi when used within combination regimens .
On this basis, we investigated whether, similarly to pan-HDACi, oleacein treatment could trigger synergistic anti-MM activity in combination with clinically-relevant proteasome inhibitors.
With this aim, NCI-H929 cells were treated with different concentrations of oleacein with or without bortezomib or carfilzomib, and subsequently cell viability was analyzed by CTG; the occurrence of synergism was assessed by Calcusyn. Interestingly, oleacein synergistically enhanced the effects of carfilzomib (CI < 1.0) on the inhibition of cell viability (Figure 5A), while combination with bortezomib was generally antagonistic (CI > 1.0; Supplementary Figure S4).
“No foods protect people against cancer completely. The term cancer-fighting foods refers to foods that may lower the risk of developing cancer if a person adds them to their diet.
This article looks at the best cancer-fighting foods and explains the science that supports these claims.
Foods that contain naturally occurring compounds that have potent anticancer properties include:
Although the foods listed above are everyday products and readily available, some people may not want to make significant dietary or lifestyle changes. In this case, there are plenty of supplements and medications available that contain anticancer compounds.
Vitamins A, C, and E are notable for their anticancer properties and are available as supplements in most major grocery stores.
Most of the plant-based compounds listed throughout this article, such as phloretin, anthocyanin, and sulforaphane, come in pill form.
Over-the-counter medications, such as aspirin and ibuprofen, may also lower the risk of cancer in some people.
Always speak to a medical professional before starting a new medication or supplement regimen.
Research into preventing cancer through diet is still in the early stages and requires further testing. Scientists carried out most of the studies mentioned in cells or mice.
However, it is important to remember that eating a balanced diet high in fresh fruits, vegetables, and good fats will benefit overall health.”
“There really should not be a debate about the use of neutropenic diet for cancer patients. Its usefulness has never been scientifically proven. However, neutropenic diets remain in place in many institutions even though their usefulness is controversial.
Neutropenic diets were once thought to be important in protecting patients from having to succumb to infection from neutropenia while undergoing chemotherapy. Although food may contain harmful organisms and research has shown that bacterial translocation is possible, recent studies have been unable to obtain significant differences between placebo and intervention groups.
The dietetic challenges neutropenic patients struggle with include decreased quality of life, malnutrition, gastrointestinal side effects, food aversion, and impaired cell-mediated immunity from vitamin deficiency. Unanswered questions in regard to the neutropenic diet include the following:
(a) which food should be included;
(b) which food preparation techniques improve patient compliance;
(c) which patient populations benefit most; and
(d) when should such a diet be initiated. Without scientific evidence, the best advice for neutropenic patients is to follow food safety guidelines as indicated by government entities…”