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PeopleBeatingCancer

Recently Diagnosed or Relapsed? Stop Looking For a Miracle Cure, and Use Evidence-Based Therapies To Enhance Your Treatment and Prolong Your Remission

Multiple Myeloma an incurable disease, but I have spent the last 25 years in remission using a blend of conventional oncology and evidence-based nutrition, supplementation, and lifestyle therapies from peer-reviewed studies that your oncologist probably hasn't told you about.

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Multiple Myeloma- Foods that Kill MM!

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Foods that starve Multiple Myeloma? Foods that build my blood? Foods that clean my liver/kidneys? Shakes vs. Smoothies? Help!

It is in the best interest of multiple myeloma (MM) patients and survivors to consider both conventional and non-conventional therapies to manage their MM. Especially if that multiple myeloma therapy is tasty and will promote  heart health and brain health.

One of the most common questions I receive and read in online MM groups is about nutrition, foods, etc. and the newly diagnosed MM. While I am the first MM survivor to go on record as saying that nutrition is not a silver bullet cure for MM, I will say that there are many studies that cite a specific food or type of food that can kill monoclonal proteins (mm cells) or support a certain condition.

 

The challenge faced by the newly diagnosed MM patient is tha there are different foods for different purposes.

I am both a MM survivor and MM cancer coach. Are you looking for nutritional anti-MM therapies? I talk about fruits, veggies, smoothies, nutraceuticals but none of these anti-cancer therapies are as easy to include in your diet as extra-virgin olive oil.

I don’t envision a MM patient or survivor relying solely on olive oil supplementation to cure his/her cancer. However I do envision cancer patients altering their daily diets to include olive oil, dark chocolate,  and organic fruits and veggies.

For more information about non-conventional multiple myeloma therapy such as nutrition or supplementation, scroll down the page, post a question or a comment and I will reply to you ASAP.

Thank you,

David Emerson

  • Long-term MM Survivor
  • MM Cancer Coach
  • Director PeopleBeatingCancer

Recommended Reading:

Oleocanthal inhibits proliferation and MIP-1α expression in human multiple myeloma cells.

“Here we report that this natural compound has a remarkable in vitro activity by inhibiting MIP-1 α expression and secretion in Multiple Myeloma cells. In addition, we also demonstrated that oleocanthal inhibits MM cells proliferation by inducing the activation of apoptosis mechanisms and by down-regulating ERK1/2 and AKT signal transduction pathways. This in vitro study suggests a therapeutic potential of oleocanthal in treating multiple myeloma…”

Anti-tumor Activity and Epigenetic Impact of the Polyphenol Oleacein in Multiple Myeloma

“Conclusions-

Our results indicate that oleacein, the most abundant EVOO secoiridoid, elicits significant anti-tumor activity by promoting cell cycle arrest and apoptosis, either as a single agent or in combination with the proteasome inhibitor carfilzomib. Moreover, our data highlight an epigenetic impact of oleacein in MM, as demonstrated by the impairment of the MM acetylome, likely via Sp1-dependent transcriptional inhibition of HDACs. Altogether, these findings provide the molecular rationale for potential epi-therapeutic anti-MM strategies based on natural agents…

Oleacein Enhances the Anti-MM Activity of Carfilzomib

HDAC inhibitors (HDACi) are part of the therapeutic armamentarium against MM, and clinical studies have shown promising therapeutic activity of pan- or selective-HDACi when used within combination regimens [].

On this basis, we investigated whether, similarly to pan-HDACi, oleacein treatment could trigger synergistic anti-MM activity in combination with clinically-relevant proteasome inhibitors.

With this aim, NCI-H929 cells were treated with different concentrations of oleacein with or without bortezomib or carfilzomib, and subsequently cell viability was analyzed by CTG; the occurrence of synergism was assessed by Calcusyn. Interestingly, oleacein synergistically enhanced the effects of carfilzomib (CI < 1.0) on the inhibition of cell viability (Figure 5A), while combination with bortezomib was generally antagonistic (CI > 1.0; Supplementary Figure S4).

The best cancer-fighting foods

“No foods protect people against cancer completely. The term cancer-fighting foods refers to foods that may lower the risk of developing cancer if a person adds them to their diet.

This article looks at the best cancer-fighting foods and explains the science that supports these claims.

Foods that contain naturally occurring compounds that have potent anticancer properties include:

Supplements and medications

Although the foods listed above are everyday products and readily available, some people may not want to make significant dietary or lifestyle changes. In this case, there are plenty of supplements and medications available that contain anticancer compounds.

Vitamins A, C, and E are notable for their anticancer properties and are available as supplements in most major grocery stores.

Most of the plant-based compounds listed throughout this article, such as phloretin, anthocyanin, and sulforaphane, come in pill form.

Over-the-counter medications, such as aspirin and ibuprofen, may also lower the risk of cancer in some people.

Always speak to a medical professional before starting a new medication or supplement regimen.

Takeaway

Research into preventing cancer through diet is still in the early stages and requires further testing. Scientists carried out most of the studies mentioned in cells or mice.

However, it is important to remember that eating a balanced diet high in fresh fruits, vegetables, and good fats will benefit overall health.”

The Benefit of the Neutropenic Diet: Fact or Fiction?

“There really should not be a debate about the use of neutropenic diet for cancer patients. Its usefulness has never been scientifically proven. However, neutropenic diets remain in place in many institutions even though their usefulness is controversial.

Neutropenic diets were once thought to be important in protecting patients from having to succumb to infection from neutropenia while undergoing chemotherapy. Although food may contain harmful organisms and research has shown that bacterial translocation is possible, recent studies have been unable to obtain significant differences between placebo and intervention groups.

The dietetic challenges neutropenic patients struggle with include decreased quality of life, malnutrition, gastrointestinal side effects, food aversion, and impaired cell-mediated immunity from vitamin deficiency. Unanswered questions in regard to the neutropenic diet include the following:

(a) which food should be included;

(b) which food preparation techniques improve patient compliance;

(c) which patient populations benefit most; and

(d) when should such a diet be initiated. Without scientific evidence, the best advice for neutropenic patients is to follow food safety guidelines as indicated by government entities…”

 

Leave a Comment:

8 comments
Diana Brumfield says 7 months ago

I recently had some labs drawn and they came back indicative of possibly MM (IGg 1890, Ferritin 600, Vit B12 1934, Monoclonal protein abnormal). I have been a clean food eater for the most part. I am interested in your thoughts on raw food juicing.

Reply
    David Emerson says 7 months ago

    Hi Diana-

    I think juicing fruits and veggies is an excellent way to get nutrition into your body. I myself did a lot of juicing when I was first diagnosed. I admit that I got lazy and found smoothies to be easier and allowed me to add powders, nuts, etc. turning this practice into a meal.

    Good luck with your probable diagnosis and let me know if you have any questions.

    David Emerson

    Reply
Diane says last year

I was diagnosed 1yr ago with MM. I responded remarkably well to my treatments and as of Feb am in remission. I have a great deal of confidence in my oncologist and how he has handled my journey with one exception. My diagnosis was do to a broken rib and it was discovered that I had a large tumor on my spine and a number of smaller ones all over my body. Consequently I had a great deal of pain in the beginning. It took a bit to get it under control do to my reluctance to using opioids. In the end I ended up on morphine. I only take 15mg extended release every 12 hrs. I have approached him several times about getting off the morphine but he is extremely reluctant to do that but I can’t understand why. I realize everyone’s pain tolerance is different but since you have dealt with this for so long what have you used for pain management. I have read several of the CBD articles and I don’t get a feeling that you are entirely sold on that as a pain management replacement for narcotics. Can you help me find a replacement for morphine. My oncologist tells me it’s a very small dosage and he feels like I should remain on it. I’m concerned about long term use. I know I’m not promised 20 yrs or even two for that matter but I don’t want to find myself down the road even 5 yrs on 50mg of morphine because we have to keep upping the dosage because of the amount of time I’ve been on it. I appreciate any input you might have for me. Thank you

Reply
    David Emerson says last year

    I replied to you via email, Diane-

    David Emerson

    Reply
Anita Whitfield says last year

My MM journey began in 2006. Tumors @ T-11 & L2, multiple back surgeries @MDAnderson, followed by autologous stem cell transplants in 2007 & 2017. Velcade Maint. shots from 2017 to 2021. Currently on Revlamid 15 mg, dex. & bi-weekly empliciti IV. Now that rev. has gone generic, my insurance co. will only pay generic. I’ve fought MM battle for 16 yrs, have exhausted all stem cell transplants & must rely on chemo.. Any input/info. is appreciated as it looks like this 65 yr old grandmother must now do some of my own research for alternatives. Can’t help but be frustrated with big pharma right now…

Reply
    David Emerson says last year

    Hi Anita-

    First and foremost Anita, you must know that are an exemplary MM survivor. Congratulations on your 16 year survival thus far. I’m guessing of course but I believe that you:

    Were stage II or stage III at diagnosis? I say this because of your bone involvement at diagnosis.
    Proof that autologous stem cell transplantation can increase overall survival aka OS.
    Proof that low-dose maintenance therapy can increase OS as well- both velcade and bortezomib in your case.

    To clarify your treatment history, your induction therapy and first ASCT stabilized you and you reached remission and stopped all therapy in ’06,’07? You enjoyed a remission until 2016-17 when you underwent a second ASCT?

    After your second ASCT, you added low-dose Velcade as maintenance therapy? And you remained in remission until 2021? At some point last year (2021) you decided to switch from Velcade maintenance to Expliciti , Revlimid, dex.?

    In my experience, your therapies going forward will depend on your MM having become refractory to a previous therapy. This is obvious, I know, I’m just laying a base…

    In theory, your mm is refractory to protease inhibitors (velcade) and immunomodulatory drugs (revlimid). Ask your onc. if you are refractory to these two classes of chemo. The link below is to info about Panobinostat combined with Velcade.

    https://cdrjournal.com/article/view/4316

    Another possibility is Daratumumab aka darzelex. Though this drug is similar to empliciti, it seems as if this therapy is different enough that it may be worth a try.

    Finally, and this therapy may have already been discussed, you can try CAR-T therapy. If you have the option, I would hold off CAR-T therapy as long as possible only because oncology seems to be improving this therapy regularly.

    Those are conventional therapy options.

    Evidence-based but non-conventional therapies would be treatments that are not FDA approved- I have read studies that cite several integrative therapies- this would be curcumin, thymoquinone, etc. enhancing the efficacy of protease inhibitors.

    Further, therapies such as antineoplaston therapy, insulin-potentiation therapy, etc. Therapies that don’t have the support of studies/research and are therefore difficult for the patient (you) to assess.

    I’m mentioning therapies that are not FDA approved simply to give you an idea of what is out there.

    I have thrown many ideas at you. Let me know if you have any questions.

    Hang in there,

    David Emerson

    Reply
Andrew Wasil says last year

Hi sir,

I found out about you through reading about a lawsuit you had against Ohio medical insurance company. My mother in law was recently diagnosed with MM. I was looking for your insight on the antineoplaston therapy.

Reply
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