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Recently Diagnosed or Relapsed? Stop Looking For a Miracle Cure, and Use Evidence-Based Therapies To Enhance Your Treatment and Prolong Your Remission

Multiple Myeloma an incurable disease, but I have spent the last 25 years in remission using a blend of conventional oncology and evidence-based nutrition, supplementation, and lifestyle therapies from peer-reviewed studies that your oncologist probably hasn't told you about.

Click the orange button to the right to learn more about what you can start doing today.

Multiple Myeloma- Enhance Bone Health w/ Probiotics-

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“Recent studies demonstrate that the GM (gut microbiota) is also a regulator of bone mass (bone health) and it is proposed that the effect of the GM on bone mass is mediated via effects on the immune system, which in turn regulates osteoclastogenesis…”

Whether we are talking about multiple myeloma (MM) itself or many of the MM therapies administered to manage one’s MM, your bone health can get hammered. MM chemo can damage your bone health and multiple myeloma therapy such as high-dose steroids (dexamethasone, prednisone) actually cause bone-loss. Therefore, non-toxic multiple myeloma therapy shown to enhance bone health are essential.

The type of cancer patient/survivor that is most at-risk of bone damage is that of an incurable blood cancer called multiple myeloma (MM):

The standard-of-care treatment for newly diagnosed MMers often  includes a bisphosphonate therapy. While drugs such as

can be an important tool in the MM patient’s toolbox, bisphophonates do have short and long-term side effects. I believe that all myeloma patients must manage toxicity at every point during their journey. Bone health therapies are no different.

While the studies linked and excerpted below are hardly conclusive when it comes to showing that probiotics enance bone health, they do point out specifics of interest to the MMer who is trying to strengthen his/her bone mineral density.

  • “Recent studies demonstrate that the GM is also a regulator of bone mass and it is proposed that the effect of the GM on bone mass is mediated via effects on the immune system, which in turn regulates osteoclastogenesis.”
  • “Throughout the duration of the study, DASH score, pain, CRPS score, wrist flexion and grip strength of patients receiving probiotics exhibited a significantly faster pace of improvement than those on placebo…”

I believe the most important finding of the studies below is the idea that probiotic supplementation can heal bone fractues significantly faster than those not supplementing with probiotics. That is to say that MM patient’s experience all manner of “bone involvement” throughout their lives as MMers. The key is to work to heal one’s bone involvement now and in the future.

I admit to taking the “more is better” approach when it comes to my own probiotic supplementation. I take Garden of Life – RAW Probiotics Men- 85 billion live cultures, 31 different strains. I can offer no research to support my thinking other than the fact that I’ve read a host of studies documenting various strains of probiotics reducing a host of different chronic diseases.

Have you been diagnosed with multiple myeloma? If so, what stage? What symptoms are you experiencing? Scoll down the page, post a question or comment and I will reply to you ASAP.

David Emerson

  • Multiple Myeloma Survivor
  • MM Cancer Coach
  • Director PeopleBeatingCancer

Recommended Reading:


Effects of the gut microbiota on bone mass.

“The gut microbiota (GM), the commensal bacteria living in our intestine, performs numerous useful functions, including modulating host metabolism and immune status. Recent studies demonstrate that the GM is also a regulator of bone mass and it is proposed that the effect of the GM on bone mass is mediated via effects on the immune system, which in turn regulates osteoclastogenesis. Under normal conditions, the skeleton is constantly remodeled by bone-forming osteoblasts (OBs) and bone-resorbing osteoclasts (OCLs), and imbalances in this process may lead to osteoporosis. Here we review current knowledge on the possible role for the GM in the regulation of bone metabolism and propose that the GM might be a novel therapeutic target for osteoporosis and fracture prevention.”

The effect of probiotic treatment on elderly patients with distal radius fracture: a prospective double-blind, placebo-controlled randomised clinical trial.

“Treatment outcomes were the DASH (disabilities of the arm, shoulder and hand) score, pain, complex regional pain syndrome (CRPS) score, active range of motion and grip strength, all of which were measured on a monthly basis. Throughout the duration of the study, DASH score, pain, CRPS score, wrist flexion and grip strength of patients receiving probiotics exhibited a significantly faster pace of improvement than those on placebo, with treatment outcomes of patients receiving Lactobacillus casei Shirota at month 4 at comparable levels with those of patients receiving placebo at month 6. In elderly patients with a fracture of the distal radius, administration of the probiotic could greatly accelerating the healing process.”

Lactobacillus reuteri reduces bone loss in older women with low bone mineral density – a randomized, placebo-controlled, double-blind, clinical trial.

“Ninety women were included and 70 completed the study. L. reuteri 6475 reduced loss of total vBMD compared to placebo both in the intention-to-treat (ITT) analysis... In general, similar but smaller effects were observed in the secondary bone variable outcomes, but these differences did not reach statistical significance in the ITT population…”

Effects of Lactobacillus helveticus fermented milk on bone cells in vitro.

“…The Lh-whey increased bone formation 1.3-1.4 times with the 1 x 10(-5), 1 x 10(-4) and 1 x 10(-3) solutions. The IPP and VPP peptides also demonstrated a significant 5-fold activation of bone formation in in vitro osteoblast cultures, whereas the sour milk whey and calcium had no effect. No significant effects were observed on osteoclasts in vitro with any of the study products. L. helveticus fermented milk whey contains bioactive components that increase osteoblastic bone formation in vitro…”

Leave a Comment:

13 comments
Angelica Griffith says a few months ago

Good evening Mr. Emerson.
My name is Angelica and my mother Lidia 85 years old is been diagnose with MM.
I’m grateful I found you over the Internet!
We have chosen alternative treatment and she seems to respond well for her. Her pain its almost gone. However her itchiness it no. I want to ask you if you might have any suggestions to treat the itchiness.
Thank you in advance for your time.
Angelica

Reply
    David Emerson says a few months ago

    Hi Angelica-

    I am sorry to learn of your mom’s MM diagnosis. It’s good to read that your mom is responding to treatment. It is difficult for me to hazard a guess as to what is causing her skin itchiness without knowing what treatments she is undergoing.

    Has your mom undergone any diagnostic testing? Blood work may be able to indicate something about red or white blood cells or if any other levels are above or below normal. Levels such as sodium, potassium, glucose, etc.

    Regardless of the type of treatment, your mom will benefit from the usual diagnostic testing in order to understand what is happening to her blood, marrow, organs, bones, etc.

    Let me know if you have any other questions.

    Good luck,

    David Emerson

    Reply
Leela jacob says a few months ago

I am diagnosed with Multiple myeloma. Advised Chemo therapy RVD treatment and radiation for back pain if needed for four months. Please let know how I need to overcome this ailment

Reply
    David Emerson says a few months ago

    Hi Leela-

    I am sorry to read of your MM diagnosis. “Overcome” this ailment as you say requires a long reply. How about if I give you tips to enhance
    your induction therapy (RVD) and therefore postponing the need for what your oncologist will push for as the next step of treatment- an autologous stem cell transplant.

    Before you begin RVD therapy, “PRE- habilitate.” Like getting in shape for the big game or for any big endeavor. Clean up your diet, try to moderately exercise daily (go for a brisk walk), take a supplement called curcumin (I will link below), try to get a good nights sleep regularly, try to stress yourself less, if at all.

    Studies show that PRE-habilitation will help your induction be more effective, help you recover from it more quickly and require fewer coursed (your oncologist may push for 5 or 6 monthly courses but if you respond well after, say 2-3, you will not have to undergo as much chemo aka toxicity.)

    The big question is the need for an autologous stem cell transplant. If you reach MRD, complete remission or very good partial remission, studied confirm that you will not benefit from an immediate ASCT and will only increase your risk of short, long-term and late stage side effects.

    As for your radiation for your back pain- if your oncologist is recommending local radiation, it means the you have a MM lesion in one of your vertebras. A little amount of local radiation can be a good thing to zap your lesion.

    Ask your oncologist about kyphoplasty/vertebroplasty (bone cement) to stabilize your spine once you nuke the lesion.

    I will email you the MM CC bone health guide to undergo non-toxic therapies to enhance your bone health.

    Let me know if you have any questions. Let me know how you do, how you feel going forward. Keep in touch and hang in there,

    David Emerson

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