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Multiple Myeloma an incurable disease, but I have spent the last 25 years in remission using a blend of conventional oncology and evidence-based nutrition, supplementation, and lifestyle therapies from peer-reviewed studies that your oncologist probably hasn't told you about.

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Cryotherapy Reduces Peripheral Neuropathy?

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“The condition (CIPN) can cause pain, numbness, and tingling, affect quality of life and often result in treatment delays, (to multiple myeloma patients) reduced treatment doses, or treatment discontinuation..”

Peripheral neuropathy is the long-term side effect that may not kill you but can make you wish you were dead. I don’t think I’m being histrionic when I say that.

I added the question mark in the headline because the study below documents how cryotherapy reduces CIPN in breast cancer patients not multiple myeloma patients. However because CIPN can be a painful multiple myeloma side effect,  I am offering cryotherapy as a possible therapy for MMers to consider- Because of the other linked study that cites the CIPN mechanism. A biological process that strikes me as being common to all chemotherapy regimens that cause CIPN.

I am trying to connect the dots below because there have been studies that document the benefits of cryotherapy for hair-loss as well. In short (from a layman’s perspective), cold seems to slow or stop the negative side effects caused by chemotherapy.

I am both a MM survivor and MM Cancer Coach. Having lived with MM since my diagnosis in early 1994 I approach MM with a patient’s perspective rather than an oncologist’s perspective.  I suffer from peripheral neuropathy myself.

To learn more about the evidence-based therapies I have followed for the past 23 years to manage my Multiple Myeloma, please watch the short video below:

Thank you,

David Emerson

  • MM Survivor
  • MM Cancer Coach
  • Director PeopleBeatingCancer

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Cryotherapy, as Frozen Gloves and Socks During Chemo, May Ease Neuropathy in Patients

“Cryotherapy, which makes use of the beneficial properties of extremely cold temperatures, could help prevent damage in the peripheral nerves of patients receiving chemotherapy, a study suggests…

Chemotherapy-induced peripheral neuropathy reflects damage to the peripheral nerves caused by chemotherapy. The condition can cause pain, numbness, and tingling, affect quality of life and often result in treatment delays, reduced treatment doses, or treatment discontinuation…

Cryotherapy was also seen to significantly delay the start of subjective neuropathy symptoms, like tactile and termosensory dysfunction…

“Ultimately a better understanding of the biologic mechanisms causing chemotherapy-induced peripheral neuropathy will improve our ability to effectively prevent and treat all components of this toxicity…””

Acupuncture Offers Protective Effect Against CIPN in Patients With Colorectal Cancer

“Patients with stage III colorectal cancer who are given acupuncture concurrently with the chemotherapy drug oxaliplatin experience some protection from chemotherapy-induced peripheral neuropathy (CIPN), according to research published in The Oncologist

The researchers observed significant changes from baseline for both groups for sensory NCV and questionnaire scores. However, they found that verum acupuncture was more protective than sham acupuncture on touch thresholds in the prevention of CIPN, and this beneficial effect on the touch threshold lasted for at least 6 months after the intervention was completed. No adverse effects were reported, they added.

“Our study found that the prophylactic use of acupuncture exerts neuroprotective effects to touch thresholds of all 4 limbs during chemotherapy and at 6 months of follow-up,” the researchers concluded. “Verum acupuncture appeared to exert a protective effect by reducing motor NCV values. Further studies with a larger sample, comprehensive assessments, and appropriate placebo controls are warranted…”

Peripheral Neuropathy After Chemotherapy: Mechanism Identified

“Researchers may have uncovered the mechanism for chemotherapy-induced peripheral neuropathy (CIPN) related to paclitaxel, according to a study published online in Neuron

Sarah E. Pease-Raissi, PhD, from Harvard Medical School in Boston, and colleagues sought to better understand the molecular mechanism of CIPN. They noted that CIPN is characterized by degeneration of long axons needed for transmission of sensory information and that there are no available treatments

“Together these data identify a Bclw-IP3R1-dependent cascade that causes axon degeneration, and suggest Bclw-mimetics could provide effective therapy to prevent CIPN,” conclude the authors.”


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Multiple Myeloma Side Effect- CIPN Therapies - PeopleBeatingCancer says a couple of years ago

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