Recently Diagnosed or Relapsed? Stop Looking For a Miracle Cure, and Use Evidence-Based Therapies To Enhance Your Treatment and Prolong Your Remission
Multiple Myeloma an incurable disease, but I have spent the last 25 years in remission using a blend of conventional oncology and evidence-based nutrition, supplementation, and lifestyle therapies from peer-reviewed studies that your oncologist probably hasn't told you about.
Click the orange button to the right to learn more about what you can start doing today.
Multiple Myeloma Patients are concerned with reaching remission. But multiple myeloma patients can’t get to remission if their side effects lead to “dose reduction.”
Chemotherapy regimens such as Velcade (bortezomib), Revlimid (lenalidomide), Cytoxan (cyclophophomide) etc, are cytotoxic (kill) to multiple myeloma but also are toxic to human beings. Toxicity can lead to collateral damage aka multiple myeloma side effects.
Don’t expect your oncologist to discuss the issue of dose reduction until you complain of debilitating side effects from your induction therapy. While every MM patient hopes to reach MRD negative status, their chances of reaching it are limited if their induction therapy leads to severe side effects such as
Evidence-based integrative therapies can both reduce toxicity of chemotherapy while enhancing the efficacy of those chemotherapy regimens. Integrative therapies can give you relief from multiple myeloma side effects.
Please watch the video below to learn more about the evidence-based, integrative therapies to combat treatment side effects and enhance your chemotherapy.
“A recent study found that patients who took 1500 mg per day (500 mg, three times per day) of a more bioavailable oral form of curcumin (Meriva) had significantly fewer symptoms while undergoing chemotherapy or radiation therapy compared with placebo.”
“Based on a review of these studies, it is evident that better bioavailability of formulated curcumin (CU) products is mostly attributed to improved solubility, stability, and possibly low first-pass metabolism”
A search of the Pubmed database for the word curcumin yields 601 studies spaning health topics from multiple myeloma and colorectal cancer, to chemotherapies that synergizes with CU, to Alzheimer’s Disease, arthritis and more. Based on years of reading studies and personal accounts, I think it is safe to say that CU supplementation is safe and relatively inexpensive.
I have read about myeloma patients taking daily doses of CU from 400 milligrams to 8 grams (1000 milligrams = 1 gram). By almost any measure, CU is a safe, inexpensive wonder drug.
The only challenge is that CU is famously difficult to absorb in the body. In other words, a person has to mix curcumin with some sort of fat (coconut oil, chocolate, etc.) or take a brand of curcumin capsule that is already formulated to be more “bioavailable” in order to derive the full benefit of CU.
The study linked and exerpted below reviews different formulations of CU. The study itself lists the three most bioavailable formulation/brand of CU and I’ve added an excerpt from a further review from Consumerlab.com that lists four additional bioavailable brands of CU.
“Curcumin is a widely studied natural compound which has shown tremendous in vitro therapeutic potential. Despite that, the clinical efficacy of the native CU is weak due to its low bioavailability and high metabolism in the gastrointestinal tract. During the last decade, researchers have come up with different formulations with a focus on improving the bioavailability of curcumin. As a result, a significant number of bioavailable curcumin-based formulations were introduced with the varying range of enhanced bioavailability.
The purpose of this review is to collate the published clinical studies of CU products with improved bioavailability over conventional (unformulated) CU. Based on the literature search, 11 curcumin formulations with available human bioavailability and pharmacokinetics data were included in this review. Further, the data on clinical study design, analytical method, pharmacokinetic parameters and other relevant details of each formulation were extracted.
Based on a review of these studies, it is evident that better bioavailability of formulated curcumin products is mostly attributed to improved solubility, stability, and possibly low first-pass metabolism. The review hopes to provide a quick reference guide for anyone looking information on these bioavailable curcumin formulations.
exhibited over 100-fold higher bioavailability relative to reference unformulated CU. Suggested mechanisms accounting for improved bioavailability of the formulations and details on the bioanalysis methods are also discussed.”
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14 comments
Angels says
a couple of months ago
Hi. Are you still around. I didn’t see any activity in comments since 4 yrs ago. My husband was recently diagnosed with MM. stage 2. Of course hustles immediately into chemo by his oncologist who explained nothing. Prepping him for stem cell which we are not doing to their demise. We have so many questions. He had terrible side effects from kyrpolis they started him on. I honestly thought he was having seizures.
I am sorry to read of your husband’s MM diagnosis. I am happy to answer any questions you may have. There is a lot I don’t know about why your onc prescribed the induction therapy for your husband, but in my experience, oncology treats MM aggressively. Having said that, it’s important to know that you and your husband are in charge. Meaning, there are many different types of induction therapy for MM patients.
A board-certified MM specialist who practices a low-dose approach to MM care is named James Berenson. His results are, on average, significantly better than those of conventional oncology. https://berensoncancercenter.com
As for your decision to have/not have an ASCT, in general, I agree. However, see how your husband responds to induction therapy. If he reaches a deep remission (CR, sCR, VGPR), the additional toxicity of an ASCT will not add much to his therapy. If, however, he only responds partially to his induction, an ASCT may take him into a deeper remission.
Let me know if you have any questions. Hang in there.
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