Multiple Myeloma an incurable disease, but I have spent the last 25 years in remission using a blend of conventional oncology and evidence-based nutrition, supplementation, and lifestyle therapies from peer-reviewed studies that your oncologist probably hasn't told you about.
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And those are just the multiple myeloma stem cell transplant side effects that I live with…
The main problem highlighted in the article linked and excerpted below is that multiple myeloma is a bone disease almost as much as it is a blood cancer.
Meaning, according to research, 80-90% of MM survivors will confront bone damage at some point during their MM experience.
People who are diagnosed with multiple myeloma are told that while myeloma is incurable it is treatable. This means that while MMers relapse and eventually succumb to this cancer, there are many chemotherapies that have the ability to kill myeloma cells.
The trick then, is to figure out which chemotherapy, singly or in combination, high-dose, low-dose, etc. will result in the greatest overall survival. This is oncology speak for length of life.
Starting in the ’90’s (I was diagnosed in ’94) the autologus stem cell transplant (ASCT) became the go-to therapy for MMers. The ASCT is aggressive, high-dose chemotherapy. There are no two ways about it. A hematopoietic stem-cell transplant can mean a host of short, long-term and late stage collateral damage.
While many MMers do experience long remissions after an ASCT, many do not. I relapsed after my ASCT in ’95 after 10 months.
Along with overall survival (OS), MMers must think about quality of life after an ASCT. The study linked and excerpted below talks about bone loss and bone fracture as late effects of HSCT.
Fortunately, there are a number of therapies, both conventional and non-conventional, that are evidence-based bone strengthening therapies such as bisphosphate therapy, vitamin D, calcium, and others.
I am both a long-term Cancer Survivor and Cancer Coach. For more information about evidence-based, non-toxic bone therapies in addition to other evidence-based but non-toxic cancer therapies, scroll down the page, post a question or a comment and I will reply ASAP.
“The number of long-term survivors after hematopoietic stem-cell transplantation (HSCT) for malignant and nonmalignant disorders is increasing, and late effects are gaining importance. Osteoporosis and fractures can worsen the quality of life of HSCT survivors, but the burden of the disease is unknown…
A total of 7,620 patients underwent an HSCT from 1997 to 2011 at the MD Anderson Cancer Center of whom 602 (8%) developed a fracture. Age, underlying disease, and HSCT type were significantly associated with fracture. Age- and sex-specific fracture incidence rates after HSCT were significantly greater than those of the US general population in almost all subgroups. The striking difference was an approximately eight times greater risk in females and approximately seven to nine times greater risk in males age 45 to 64 years old when compared with the National Health Interview Survey and National Hospital Discharge Survey fracture rates.
Conclusion The incidence of fractures is compellingly higher after HSCT.”