Multiple Myeloma an incurable disease, but I have spent the last 25 years in remission using a blend of conventional oncology and evidence-based nutrition, supplementation, and lifestyle therapies from peer-reviewed studies that your oncologist probably hasn't told you about.
Click the orange button to the right to learn more about what you can start doing today.
The bad news is that if you underwent certain chemotherapy regimens to treat multiple myeloma your risks of heart disease increase annually. The good news? You can do something about it. I am a multiple myeloma survivor who underwent several cardio-toxic chemotherapy regimens.
I underwent a chemo called adriamycin in the Spring/Summer of ’95 and cytoxan, busulfan and melphalan in the Fall of the same year. All four of those chemotherapy regimens cause heart damage. I developed chronic atrial fibrillation in the fall of 2010.
Once I developed A-fib I began researching evidence-based, non-toxic therapies for heart health. The study linked and excerpted below cites exercise as a therapy. I do that daily in addition to nutrition and heart healthy supplementation.
The good news is that I just had a complete work-up with two different cardiologists over the past two months (fall of 2015). My echo, ekg, etc. tests confirm that my ejection fraction is stable. My distending aortic root has NOT grown since my last echo in 2006.
I’m not saying that my heart function is normal. I’m saying that my long list on non-coventional therapies such as frequent moderate exercise, CoQ10, omega 3 fatty acids and others, is keeping my chemo-induced heart damage from getting worse. Scroll down to read the many health benefits provided by omega-3 fatty acid supplementation.
I am both a MM survivor and MM cancer coach. For more information about therapies to manage chemo-induced or radiation-induced heart damage scroll down the page and post a question. I will reply ASAP.
Preclinical studies have elucidated the underlying cardiac pathomechanisms of irreversible proteasome inhibition by carfilzomib. However, the molecular mechanisms are not yet fully understood, and only few cardioprotective strategies have been tested in preclinical studies and practically none in clinical studies.
Few case series have been published indicating that medication withdrawal or dose reduction and heart failure medication might reverse cardiomyopathy in some cases (23,52,53). Some of them report resolved cardiac dysfunction without discontinuation of carfilzomib (53). These findings have to be systematically confirmed in clinical studies. Meanwhile, cardiovascular toxicity under carfilzomib therapy could be addressed by reducing the dose, changing to bortezomib or ixazomib based regimens, and treating the cardiovascular side effects according to current guidelines (54,55).
So far, there is no risk stratification available. Baseline echocardiography, cardiovascular risk factors, and biomarkers are not conclusive when assessing the individual risk for cardiotoxicity (20,21)…
“The treatment of multiple myeloma is considered a continuously evolving paradigm as a result of the growing availability of new and highly effective drugs, including first- and second-generation proteasome inhibitors, immunomodulatory agents, and monoclonal antibodies…
Although the overall toxicity profile of the recommended regimens can be considered favorable, their increasing complexity and prolonged use warrant a heightened vigilance for early and late side effects, a priori because real-life patients can be more frail or present with 1 or more comorbidities…
Accurate knowledge in recognizing and managing the potential side effects of present-day treatment regimens is therefore a cornerstone in myeloma care. Using 5 case vignettes, we discuss how to prevent and manage the most common nonhematological adverse events of anti–myeloma treatment regimens containing proteasome inhibitors, immunomodulatory drugs, and monoclonal antibodies…”
I’m a long-term cancer survivor living with chemobrain, chemo-induced heart damage, radiation-induced nerve damage and a risk of treatment related secondary cancers. I believe that omega 3 fatty acid supplementation helps me maintain my health each and every day.
I take one capsule daily of Life Extension Super Omega 3 EPA/DHA with Sesame Lignans and Olive Fruit to insure all I get all of the health benefits below and I encourage you to do so as well.
Metabolic syndrome is a collection of conditions.
It is a major public health concern, since it increases your risk of developing many other diseases. These include heart disease and diabetes (51).
Inflammation is incredibly important. We need it to fight infections and repair damage in the body.
Cancer is one of the leading causes of death in the Western world, and omega-3 fatty acids have long been claimed to reduce the risk of certain cancers.
Asthma is a chronic lung disease with symptoms like coughing, shortness of breath and wheezing.
Menstrual pain occurs in the lower abdomen and pelvis, and often radiates to the lower back and thighs.
Good sleep is one of the foundations of optimal health.
Omega-3s can also protect your skin from sun damage. EPA helps block the release of substances that eat away at the collagen in your skin after sun exposure (101).