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Multiple Myeloma Treatment- Antibiotic Prophylaxis?

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“…this result (less infection) was marginal in terms of statistical significance and that the risk of mortality appeared unaffected by antibiotic prophylaxis.”

If your immune system is in bad shape when you receive your multiple myeloma diagnosis, should you undergo antibiotics to prevent infections? Should prophylactic antibiotics be a part of your multiple myeloma treatment?

As the article linked and exempted below explains, conventional  prophylactic antibiotic use as a multiple myeloma treatment will reduce your risk of infection a bit but:

  • prophylactic antibiotics won’t reduce your risks much
  • it will not reduce your risk of mortality and
  • comes with potentially serious side effects

Consider taking a complementary/integrative approach to prophylactic antibiotics.

First and foremost, we know that most newly diagnosed MM patients have an increased risk of infection. The key is to figure out how to reduce that risk without relying on conventional antibiotics. Like combining conventional MM chemotherapy with non-conventional MM therapies, I believe that the patient benefits from less toxicity and fewer side effects.

I’m not saying that “natural antibiotics” are a silver bullet. I saying that, according to research, conventional prophylactic antibiotic MM treatment just doesn’t make sense. It isn’t worth it.

But reducing the dose of conventional antibiotics while adding evidence-based, natural antibiotics may get the newly diagnosed MM patients a reduced risk of infection combined with few side effects.

Have you been diagnosed with multiple myeloma? To learn more about both conventional and non-conventional multiple myeloma treatments, scroll down the page, post a question or comment and I will reply to you ASAP.

Hang in there,

David Emerson

  • MM Survivor
  • MM Coach
  • Director PeopleBeatingCancer

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Antibiotic Prophylaxis Shown to Reduce Infection Risk for Patients With Newly Diagnosed Multiple Myeloma

“For patients with newly diagnosed multiple myeloma (MM), the use of prophylactic antibiotics soon after diagnosis shows a trend of reducing infection risk, but it appears to have no effect on mortality, according to a recent pooled analysis published in the European Journal of Haematology.

In this meta-analysis of 3 randomized, controlled trials, patients with MM were evaluated for 3-month incidences of infection and mortality associated with either antibiotic prophylaxis (n=664) or a lack of antibiotic prophylaxis (control group; n=650).

The 3-month infection incidence was 18.4% among patients given antibiotic prophylaxis and 23.4% for the control group (risk ratio [RR], 0.79 [95% CI, 0.62-1.00]; P =.05). Grade 3 to 4 infections occurred in 8.0% of patients given antibiotic prophylaxis, while the incidence was 14.8% in the control group (P =.08).

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In a subgroup analysis by type of antibiotic, patients receiving prophylaxis with sulfamethoxazole/trimethoprim did not show a significantly different infection rate compared with the control (P =.45). However, fluoroquinolone prophylaxis was associated with a lower infection rate (P=.049).

The 3-month incidence of mortality did not differ statistically between the prophylaxis and control groups, with rates of 1.5% for those given antibiotics and 3.5% for the control (RR, 0.47 [95% CI, 0.17-1.27]; P =.60).

The investigators indicated that prophylactic antibiotics given during the first 2 to 3 months after MM diagnosis may reduce the incidence of infection at 3 months postdiagnosis. However, they noted that this result was marginal in terms of statistical significance and that the risk of mortality appeared unaffected by antibiotic prophylaxis.”

Common Side Effects from Antibiotics, and Allergies and Reactions

“All medications have side effects, including antibiotics. Antibiotics are medications that treat infections by killing bacteria or other organisms or slowing their growth. An antibiotic side effect occurs as an unwanted reaction that occurs in addition to the desirable therapeutic action of the antibiotic you are taking. Side effects of antibiotics can range from mild allergic reactions to severe and debilitating adverse events. When used appropriately, most antibiotics are relatively safe with few side effects. However, some side effects may interfere with your ability to finish the medication. In these cases, you should contact your doctor…”

10 most powerful natural antibiotics known to mankind

Choosing a Natural Antibiotic

Antibiotics can fight bacteria, fungi, and some parasites, but not viruses. That’s why doctors won’t prescribe you antibiotics for a viral infection or flu. In the same way, you shouldn’t attempt to use natural antibiotics to fight viruses- they simply won’t do anything. Natural antibiotics can be further divided into antibacterials and antifungals. While medicinal antibiotics are usually designed to do both, nature’s variety usually has pretty specific functions…

15 Impressive Herbs with Antiviral Activity

“Since ancient times, herbs have been used as natural treatments for various illnesses, including viral infections.

Due to their concentration of potent plant compounds, many herbs help fight viruses and are favored by practitioners of natural medicine.

At the same time, the benefits of some herbs are only supported by limited human research, so you should take them with a grain of salt.

Here are 15 herbs with powerful antiviral activity…”


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