Recently Diagnosed or Relapsed? Stop Looking For a Miracle Cure, and Use Evidence-Based Therapies To Enhance Your Treatment and Prolong Your Remission

Multiple Myeloma an incurable disease, but I have spent the last 25 years in remission using a blend of conventional oncology and evidence-based nutrition, supplementation, and lifestyle therapies from peer-reviewed studies that your oncologist probably hasn't told you about.

Click the orange button to the right to learn more about what you can start doing today.

Multiple MyelomaTherapy- Thymoquinone both Cytotoxic and Integrative

Share Button

“In the present report, we investigated whether thymoquinone (TQ), the main component isolated from the medicinal plant Nigella sativa, modulated the STAT3 signalling pathway in MM cells…”

Living with multiple myeloma (MM) since 2/1994 has taught me one clear truth. Depending on type and stage of your MM, conventional multiple myeloma therapies aren’t enough for the majority of multiple myeloma patients, survivors and caregivers. Don’t take my word for it, ask your oncologist if the multiple myeloma therapy that he/she is recommending to manage your MM is curative. It isn’t.

Thymoquinone (TQ) is an example of a non-conventional, evidence-based, non-toxic therapy that kills several types of cancer by itself and can enhance the efficacy of bortezomib/velcade as the studies linked and excerpted show. The studies below cite thymoquinone as a cytotoxic to multiple myeloma and can enhance the efficacy of chemotherapy to MM.

Further, an anti-angiogenic diet, intravenous vitamin C therapy and frequent, moderate exercise are all well-documented complementary therapies for the MM patient or survivor.

I recommend Herbal Secrets Black Seed Oil Natural Dietary Supplement- This brand of thymoquinone is well-reviewed on Amazon and is their best seller.

I am a MM survivor and MM cancer coach. For more information about integrative therapies, scroll down the page, post a question or comment and I will reply ASAP.

Thank you,

David Emerson

  • MM Survivor
  • MM Cancer Coach
  • Director PeopleBeatingCancer

Recommended Reading:

Thymoquinone inhibits proliferation, induces apoptosis and chemosensitizes human multiple myeloma cells through suppression of signal transducer and activator of transcription 3 activation pathway

“In the present report, we investigated whether thymoquinone (TQ), the main component isolated from the medicinal plant Nigella sativa, modulated the STAT3 signalling pathway in MM cells…

TQ also significantly potentiated the apoptotic effects of thalidomide and bortezomib in MM cells.


Our study has identified STAT3 signalling as a target of TQ and has thus raised its potential application in the prevention and treatment of MM and other cancers…

Thymoquinone overcomes chemoresistance and enhances the anticancer effects of bortezomib through abrogation of NF-κB regulated gene products in multiple myeloma xenograft mouse model.

“Multiple myeloma (MM) is a B cell malignancy characterized by clonal proliferation of plasma cells in the bone marrow. With the advent of novel targeted agents, the median survival rate has increased to 5 -7 years.

However, majority of patients with myeloma suffer relapse or develop chemoresistance to existing therapeutic agents. Thus, there is a need to develop novel alternative therapies for the treatment of MM.

Thus in the present study, we investigated whether thymoquinone (TQ), a bioactive constituent of black seed oil, could suppress the proliferation and induce chemosensitization in human myeloma cells and xenograft mouse model. Our results show that TQ inhibited the proliferation of MM cells irrespective of their sensitivity to doxorubicin, melphalan or bortezomib…

TQ also potentiated the apoptotic effects of bortezomib in various MM cell lines through the activation of caspase-3, resulting in the cleavage of PARP.

Overall, our results demonstrate that TQ can enhance the anticancer activity of bortezomib in vitro and in vivo and may have a substantial potential in the treatment of MM…”

Thymoquinone as an anticancer agent: evidence from inhibition of cancer cells viability and invasion in vitro and tumor growth in vivo.

“Exposure of cells derived from lung (LNM35), liver (HepG2), colon (HT29), melanoma (MDA-MB-435), and breast (MDA-MB-231 and MCF-7) tumors to increasing TQ concentrations resulted in a significant inhibition of viability through the inhibition of Akt phosphorylation leading to DNA damage and activation of the mitochondrial-signaling proapoptotic pathway…

In view of the available experimental findings, we contend that thymoquinone and/or its analogues may have clinical potential as an anticancer agent alone or in combination with chemotherapeutic drugs such as cisplatin.”

Leave a Comment:

1 comment
Add Your Reply