Myeloma and Bovine Colostrum?

Myeloma and Bovine Colostrum? Yes, according to the research linked below. I combine the two because I am a long-term MM survivor, and I began including bovine colostrum powder in my smoothie each morning.

I am the first MM survivor to recommend that nutrition starts with a healthy diet. At the same time, I am compelled to tell my fellow MM survivors what other supplements I add to my healthy diet.

As MM survivors all know, remission, relapse, remission, etc., wear us down—especially our immune system and our gut health.

In the video below, Dr. Berg talks about the importance of gut health. There is a growing number of studies that cite the importance of gut health for MM patients.

What Is Colostrum ?

MM patients and survivors often turn to their oncologists and ask them about supplements of various types. Unfortunately, conventional medicine isn’t usually knowledgeable about nutritional supplements that are not FDA-approved. That’s fine. This is just how conventional medicine works.

Email me at David.PeopleBeatingCancer@gmail.com to learn more about managing your MM with both conventional and non-conventional therapies.

Good luck,

David Emerson

MM Survivor
MM Cancer Coach
Director PeopleBeatingCancer

Immunomodulatory potential of bovine colostrum: a holistic perspective on health, disease resistance, and aging

Abstract

Bovine colostrum (BC), rich in nutrients and bioactive components, is utilized in supplements that target a variety of health issues. These include:

diabetes,
inflammatory bowel disease,
various skin illnesses,
immunological and allergy problems,
cardiovascular diseases,
and neurological disorders like aging, dementia, and Alzheimer’s.

BC is also known to improve sports performance. BC’s promise in non-pharmaceuticals and nutraceuticals is supported by the current chapter’s preclinical and clinical findings.

Growth factors, oligosaccharides, B-type vitamins, and immunoglobulins (IgG, SIgA, IgM, IgA, IgD, and IgE) are all present. Because of its anti-inflammatory and antioxidant qualities, lactoferrin, and lactalbumin in BC are very crucial in cancer treatment.

In addition to lowering body fat, BC promotes the growth of the gastrointestinal tract, the immunological system, and muscle mass. Additionally, colostrum-based goods are readily accessible in global marketplaces and include powder, pills, and traditional food items.

Given the exorbitant prices of synthetic medications, especially in areas with limited resources, BC offers a practical and reasonably priced substitute. Further investigation into the effectiveness of BC in treating viral infections, such as COVID-19, may shed more light on its possible medical uses…

Biological activity of colostrum bioactive components

The complex nutrient-rich biological fluid known as colostrum is produced by female mammals as the first nourishment after birth. It gives a young animal a high-quality, nutritious diet and helps them establish their immunity by promoting development, tissue repair, and immunity^[5](Table 1 & Fig. 1)…

Bioactive proteins

Immunoglobulins

White blood cells’ main protein fraction of BC, immunoglobulins, which include antibodies like immunoglobulin G (IgG), Secretory Immunoglobulin A (SIgA), immunoglobulin A (IgA), immunoglobulin M (IgM), immunoglobulin E (IgE), and immunoglobulin D (IgD) and make up a sizable amount of the colostrum’s total protein, are essential for providing passive immunity to infants^[10]…

Lactoferrin

A type of glycoprotein that is a member of the transferrin family, lactoferrin has an exceptionally high affinity for iron, around 260 times more than serum transferrin. Mammals’ milk and colostrum, along with several other body secretions, contain it in large quantities. Its antibacterial, antifungal, antiviral, anticancer, anti-inflammatory, and antioxidant qualities allow it to perform a variety of roles in improving health^[21]…

Growth factors

To support growth and development in newborn calves, BC contains a variety of growth factors, such as insulin-like growth factors (IGF-I and IGF-II), platelet-derived growth factors (PDGF), transforming growth factors (TGF-β1 and TGF-β2), fibroblast growth factors (FGF1 and FGF2), epidermal growth factor (EGF), and betacellulin (BTC)^[2,28]. These are the comparatively adaptable polypeptides that cause cell surface receptors to either differentiate or proliferate cells^[26]…

Enzyme

Renowned for its diverse composition, BC contains a wide range of enzymes essential for many physiological functions, such as lactoperoxidase, proteinases, lysozyme, ribonucleases, cysteine-protease, alkaline phosphatase, and lipase, all of which are vital for digestion, immunity, and general health…

Interleukins and cytokines

Interleukins and cytokines are crucial for initiating and regulating immune responses. They act as signaling molecules that communicate between cells to trigger the body’s defense mechanisms against infections. Beyond defense, they are involved in maintaining homeostasis within the body^[19,40]. For instance, they help regulate cell growth, repair tissues, and control the mechanisms of inflammation. Given that a significant part of the immune system is associated with the gut, cytokines influence gut health by managing the balance of inflammatory and anti-inflammatory responses, which can affect overall wellness and digestion^[3,41]. Cytokines and interleukins enhance the body’s resistance to diseases by mobilizing immune cells like macrophages, T cells, and B cells to sites of infection, optimizing the clearance of pathogens…

Amino acids

Amino acids, the organic molecules that serve as the foundational components of proteins, primarily consist of carbon, hydrogen, and nitrogen atoms^[42]. These vital nutrients are grouped into three categories: essential, which must be obtained through diet; semi-essential, which is necessary under specific physiological conditions; and non-essential, which can be synthesized by the body^[43]…

Nutritional components

Vitamins

BC, containing varying concentrations of fat-soluble vitamins (vitamins A, D, and E), and water-soluble vitamins (vitamins B and C) influenced by factors like lactation stage and maternal diet, is essential for human health due to its rich content of these vital nutrients^[46]. In the complex matrix of BC, which is highly valued for its diverse nutritional profile, several vital vitamins, most notably vitamin A, are found in various metabolites such as retinal, retinoic acid, retinol, retinyl ester, and beta-carotene…

Minerals

Recent studies have unveiled that the mean concentrations of numerous essential minerals in colostrum markedly surpass those found in mature bovine milk, highlighting its unparalleled richness in trace and major minerals, predominantly present as ions or colloidal species intricately complexed with the casein protein^[26]…

Fatty acids

Fatty acids (FAs) in milk fat are critical components of the human diet, providing a range of health benefits^[8]. Although colostrum is often overlooked for its fat content, it plays a vital role in nutrition and thermogenesis, helping to regulate body temperature^[2]. However, concerns have been raised regarding colostrum fat due to its higher levels of saturated FAs, which have been linked to health issues such as obesity, weight gain, and cardiovascular diseases^[19]…

Carbohydrates

Carbohydrates exist as complex compounds either in conjunction with lipids and proteins or as standalone entities in BC. This includes a variety of complex carbohydrates such as oligosaccharides, glycoproteins, nucleotide sugars, and mucins^[2]…

Medical applications of BC

Enhancing immune function
Gastrointestinal health promotion

Conclusions

This systematic review, encompassing 187 published sources, examines the composition of BC, the factors affecting it, its function as a dietary supplement (commercial and traditional), the outcomes of clinical studies, and the health benefits of each component. This comprehensive overview guarantees that we are adequately informed. Given the varied research evidence, we can assert that BC is the ‘single most important food in the world…

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