Diagnosed with Cancer? Your two greatest challenges are understanding cancer and understanding possible side effects from chemo and radiation.  Knowledge is Power!

Learn about conventional, complementary, and integrative therapies.

Dealing with treatment side effects? Learn about evidence-based therapies to alleviate your symptoms.

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Neuropathic Pain Therapies

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Neuropathic pain caused by chemotherapy is not well studied and poorly controlled by conventional oncology.  My definition of this sometimes short and/or long-term side effect  is simply the tingling, numbness and burning pain in a cancer survivors hands and feet caused by chemo regimens as varied as:

  • taxanes,
  • platinums,
  • vinca alkaloids,
  • epothilones,
  • eribulin,
  • bortezomib and 
  • lenalidomide

Like my blood cancer, multiple myeloma, if there is no reasonably affective conventional therapy to undergo, patients and survivors will inevitably turn to anything that might help.

The four studies linked and excerpted below offer four different types of evidence-based but non-conventional therapies to try.

For one of the most complete discussion of chemotherapy-induced peripheral neuropathy and potential therapies- click now. 

The two posts linked below offer additional evidence-based neuropathic pain therapies.

Are you struggling with neuropathic pain? Scroll down the page, post a question or comment and I will reply to you ASAP.

Hang in there.

David Emerson

  • Cancer Survivor
  • Cancer Coach
  • Director PeopleBeatingCancer

IV Ketamine Shown to Be Effective and Safe for Cancer-Related Neuropathic Pain

“According to research results published in Pain Medicine, intravenous (IV) ketamine has shown to be an effective and safe protocol for the treatment of cancer-related neuropathic pain (CNP) in patients with refractory pain control…

According to researchers, “Each patient’s pain was identified as being secondary to direct tumor compression (n = 13), CIPN (n = 25), surgery (n = 13), or radiation (n = 6).”According to researchers, “Each patient’s pain was identified as being secondary to direct tumor compression (n = 13), CIPN (n = 25), surgery (n = 13), or radiation (n = 6)…”

Overall, 73.7% (P<0.01) of the patients were responders. While on the IV ketamine protocol, all responders reported having improvement in function and mobility. Of the 42 responders, 26.7% (P=0.0003) discontinued treatment due to unsatisfactory pain relief or adverse effects. 71.8% of the responders had pain relief for more than 3 weeks (P< 0.01)…

Effect of cannabis on oxaliplatin-induced peripheral neuropathy among oncology patients: a retrospective analysis

“Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a common and dosage-limited oxaliplatin-related toxicity. To date, there are no successful interventions for CIPN prevention or treatment. A therapeutic role for cannabis in diabetic and HIV-related peripheral neuropathy and a protective role in CIPN have been suggested. We examined the effect of cannabis on oncologic patients with CIPN…



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