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Neuroprotective Effects of Coffee?

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Neuroprotective effects of coffee? Coffee helps my gut health, aka microbiome, gets me started each morning, and now research is telling me that coffee helps my chemobrain, too?

I almost forgot. Coffee enhances my heart health. Another of those chemotherapy-induced side effects is heart damage.

I am a long-term MM survivor. I live an anti-cancer, pro-healthy lifestyle in hopes of remaining cancer-free while I manage my long-term side effects and cancer pain.

I have linked this video for several reasons. First and foremost, the video includes specific biological info while keeping the tone light. Secondly, and most importantly, the video hits coffee’s effect on cognitive functions hard.



The bottom line is that if you are a MM survivor with chemobrain, consider having a couple of cups of joe each morning. Your brain will thank you.

Email me at David.PeopleBeatingCancer@gmail.com to learn more about both conventional and non-conventional MM therapies.

Good luck,

David Emerson

  • MM Survivor
  • MM Cancer Coach
  • Director PeopleBeatingCancer

Neurocognitive and Neurological Effects of Coffee and Caffeine: A Narrative Review

Abstract

Coffee, a popular beverage, is surprisingly complex and increasingly studied for its potential health benefits. In particular, coffee contains caffeine, which may play a role in alertness, cognition, and memory. Coffee also contains an abundance of polyphenols and other compounds, which may confer specific health benefits.

It is well known that coffee drinking can ward off drowsiness and fatigue, but the mechanisms behind this are not clearly understood. The caffeine in coffee can inhibit adenosine, but this mechanism is not well understood.

Whether or not coffee has protective effects against neurodegenerative conditions is being actively studied. Coffee may confer significant neuroprotective, anti-inflammatory, and cognitive benefits, which are of particular interest in aging populations and warrant greater study. A challenge in studying coffee’s neurocognitive aspects is that there are multiple types of coffee, and “dosing,” or how much coffee is consumed over time, can vary widely among studies…

Caffeine and cognition

Nearly all of the caffeine in coffee (99%) is absorbed in the stomach and small intestine within 45 minutes after ingestion [43]; it is metabolized via the cytochrome (CYP) 1A2 enzyme to mono-methylxanthine, dimethylxanthine, and methylated uracil derivatives [44]. Caffeine inhibits lipid peroxidation and can reduce the production of reactive oxygen species (ROS), thereby potentially reducing oxidative stress [45]. Caffeine enhances the activity of glutathione S-transferase and can prevent derangement and apoptosis of red blood cells [46]. Caffeine scavenges hydroxyl radicals, which support its neuroprotective effects [1]

Conclusions

Coffee is a natural, widely consumed, and complex natural product whose regular use has been linked to protection against neurodegenerative disorders, in particular Alzheimer’s and Parkinson’s diseases. It is not clear if the benefits of coffee are derived from caffeine or any of the other components of coffee, such as its numerous phytochemicals, and it is not unreasonable to think coffee’s benefits may involve an additive or synergistic interplay of multiple substances.

The evidence suggests that coffee may offer neuroprotective benefits, improve cognition and memory, alter brain morphology, and enhance attention.

Given that chronic pain is known to impair cognitive function, coffee’s mild analgesic benefits may also contribute indirectly to cognitive preservation. These complementary pathways highlight coffee’s complex, multimechanistic influence on the aging brain. With our graying population, these potential neuroprotective effects of coffee warrant further study.

Neuroprotective effects of coffee Neuroprotective effects of coffee Neuroprotective effects of coffee

 

 

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2 comments
Steve romanelli says a couple of weeks ago

sometimes got ice coffee at wawa but has alot of sugar going to try black coffee with cream thanks for this info

Reply
    David Emerson says a couple of weeks ago

    Hi Steve-

    I agree that sugar causes problems.

    David Emerson

    Reply
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