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Probiotics as Therapy for Inflammatory Bowel Disease assoc. Colorectal Cancer

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“These results suggest that alteration of the gut microbiome with probiotics may become a new preventative or therapeutic strategy for patients at risk for inflammatory bowel disease (IBD)-associated Colorectal Cancer”

If you have inflammatory bowel disease (IBD), you have an elevated risk of colorectal cancer. If your IBD has already resulted in a diagnosis of colorectal cancer, then hopefully you caught the CC early in its developement and therefore your prognosis is good.

Either way, you have an interest in probiotics. Specifically, according to the research below, a probiotic called Lactobacillus reuteri 6475 may help both your IBC as well as your CC.

The question you may be asking yourself is “how do I get lacto- whatever its called into my gut?” And the answer is to consider a probiotic called Garden of Life RAW Probiotics Colon Care Shelf Stable. Though the label doesn’t distinquish which numbered strain of lactobacillus is contained in this probiotic, the label does list 10 different lactobacillus strains contained in each capsule.

Have you been diagnosed with IBD? Have you been diagnosed with CC? Would you like to learn about other complementary colon cancer therapies such as fiber, omega-3 fatty acids or curcumin? Scroll down the page, post a question or comment and I will reply to you ASAP.

Thank you,

David Emerson

  • Cancer Survivor
  • Cancer Coach
  • Director PeopleBeatingCancer

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Inflammatory bowel disease

Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine. Crohn’s disease and ulcerative colitis are the principal types of inflammatory bowel disease…

While patients of IBD do have an increased risk of colorectal cancer, this is usually caught much earlier than the general population in routine surveillance of the colon by colonoscopy, and therefore patients are much more likely to survive…”

New research on probiotics in the prevention and treatment of colon cancer

“These results suggest that alteration of the gut microbiome with probiotics may become a new preventative or therapeutic strategy for patients at risk for inflammatory bowel disease (IBD)-associated CRC…

Experimental mice were orally administered the probiotic Lactobacillus reuteri 6475, which is known to possess the histidine decarboxylase gene (hdc+) and is able to convert histidine to histamine; control animals received a placebo. The probiotic was administered both before and after the mice received a single dose of a colonic carcinogen (azoxymethane) plus an inflammation-inducing chemical (DSS) to induce tumor formation. Fifteen weeks later, the mice were sacrificed and the tissues removed for study…

The active probiotic also reduced inflammation induced by the carcinogen plus DSS…

“These observations are consistent with the conclusion that histamine-generating probiotic L. reuteri may attenuate AOM+DSS-induced colon carcinogenesis, at least in part, via enhanced maturation of circulating myeloid cells and concomitant reduction of pro-inflammatory cytokines.”

Probiotic use decreases intestinal inflammation and increases bone density in healthy male but not female mice.

“Osteoporosis can result from intestinal inflammation, as is seen with inflammatory bowel disease. Probiotics, microorganisms that provide a health benefit to the host when ingested in adequate amounts, can have anti-inflammatory properties and are currently being examined to treat inflammatory bowel disease…

 

 

 

 

 

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