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Are you related to the physicist named Robert Oppenheimer? I have a distant relative who worked on the Manhattan Project. Great name.
I am sorry to learn of your various health challenges.
Several things. Long-term PPI use is associated with several serious health problems. I would have to do more research but I believe that it is reasonable to believe that at least some of your health challenges are related to your long-term PPI use.
There may be a link between your MGUS and BE-
If you have discontinued PPI’s I think the real question is the relation between Zantac and MGUS and MM. As you can read from the study linked below Zantac use can prevent abosorbtion of minerals. This reduced mineral absorbtion can weaken your bones. MGUS can weaken bones.
Bone mineral density in patients taking H2-receptor antagonist.
In short, long-term PPI use causes a host of health issues including malabsorbtion of minerals. MGUS is a blood disorder but it can lead to bone health problems. I cannot say if PPI use leads to MGUS…
I encourage you to consider the Pre-Myeloma Cancer Coaching program. Not only will you undergo bone health therapies but one key supplement called curcumin reduced the risk of MM as well as reduces the risk of your BE becoming esophageal cancer.
Let me know if you have any questions.
Thanks and hang in there,
I was Dx’d with BE a year & a half ago, & took PPI’s till now. With my doctor’s advice, I stopped Protonix 10 days ago, started on 300 mg Zantac, & my GERDS is back in force – stomach aches, belching, & acid reflux. I already take probiotics & tumeric, could add aloe vera juice. What other natural remedies can I try?Reply
While the link below takes you to a long article I believe that you will find much of the info pertains to your situation. There are several therapies for your situation in the article. Let me know if you have any questions.
Thank you for this article, I was dx with BE in August, 2016 and have chosen not to take PPIs. I have an integrative Doctor and I am taking a huge dose of live probiotic (100 billion) each day and I am going to start Aloe Vera Juice (with the non-laxative effect, I can only find it in Australia “Nutralife Aloe Vera”. I would appreciate any information you may be able to share with me. Thank you.Reply
It sounds as though you are on the right track in managing your BE. The one evidence-based, non-toxic therapy that you should consider adding to your regime is curcumin. Please click this link to read more about curcumin on BE and EC.Reply
I was diagnosed with BE in 2000 and was on PPIs for over 15 years. I finally got off them 18 months ago and switched to Zantac (three 75mgs tabs a day).
Like Carolyn I had an initial return of symptoms, but these calmed down fairly quickly with the Zantac. I think the tendency to have a rebound effect is a very scary issue. I had tried to stop several times before and restarted due to pain.
But the truth is once I got through that stage I have been really comfy on my new regime..
I have had two episodes of pneumonia in tbe past and issues with weight gain, poor circulation in my legs and muscle loss/pain in my arms. I have also had memory problems. Most of these issues have begun to improve since stopping the PPI.
I also have MGUS so
am at risk for Multiple Myeloma and wonder if MGUS/MM could be another risk with taking PPIs?