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Red Wine and Myeloma
I am a long-term survivor blood cancer called multiple myeloma. Because I enjoy a glass of wine with dinner most nights, I am continually looking for research into the pros and cons of red wine and myeloma.
As you can see from the long list of treatment-induced side effects in the link above, I worry about my heart, brain, etc. health.
The study linked below focuses mainly on the polyphenol content of red wine. The three emails linked below illustrate how I think about both polyphenols as well as red wine for MM patients.
- Lower Hypertension w/ Polyphenols
- Myeloma and Infection!?
- Can Multiple Myeloma Survivors Drink Red Wine???
What is Resveratrol?
I will be direct. Resveratrol, polyphenols, etc. in red wine are icing on the cake. I have a glass of red wine with dinner because it relaxes me not because I think red wine is good for my health. But research like the info below as well as the video above give me hope that wine, in moderation, is okay for me.
Do you have MM? What do you think about drinking red wine? Email me at David.PeopleBeatingCancer@gmail.com and let me know what you think.
Thanks,
David Emerson
- MM Survivor
- MM Cancer Coach
- Director PeopleBeatingCancer
Beneficial Effects of Red Wine Polyphenols on Human Health: Comprehensive Review
Abstract
Polyphenols are secondary plant metabolites synthesized during the development of the grape berry as a response to stress conditions. They are important constituents in red wines that contribute to the sensory properties and antioxidant activity of wines.
Due to the development of highly sophisticated analytical devices, it is now possible to characterize the structure of highly polymerized polyphenols and obtain a full polyphenol profile of red wines.
Red wine polyphenols include the ones present in grapes as well as new polyphenol products formed during the winemaking process. Among them, the most important groups and their representatives are
- flavanols (catechin),
- stilbenes (trans-resveratrol),
- flavonols (quercetin)
- and hydroxybenzoic acids (gallic acid).
It is known that polyphenols exhibit beneficial effects on human health, such as
- anti-inflammatory,
- anticarcinogenic a
- nd cardio-protective effects.
Many studies have been conducted on the health effects of red wine polyphenols in cancer chemopreventive activities, neuroprotective effects and impact on cardiovascular diseases, gut microbiota in humans, etc.
This review will provide major scientific findings on the impact of red wine polyphenols on human health as well as a review of polyphenols present in red wines and their main features…
Over 500 compounds have been characterized in wine so far and the main components are sugars, organic acids, alcohols, minerals, pigments, polyphenols, nitrogenous substances, gums, pectins, mucilages, volatile compounds, salts, vitamins and sulfur dioxide [1,3]. Major bioactive compounds in wine are ethanol and polyphenols [3]. Polyphenols are secondary metabolites of plants widely present in fruits, vegetables and their derived products…
A glass of red wine contains around 200 mg of total polyphenols, while in the same quantity of white wine, there is around 30 mg of total polyphenols [3]…
Polyphenols possess many biological properties, such as anti-inflammatory responses, antiviral, carcinostatic properties, prevention of low-density lipoprotein oxidation, antihypertensive effect, antimicrobial, antiaging properties, etc. [10,12].
Further, higher polyphenol exposure resulted in lower levels of inflammatory biomarkers [13]. An explanation of some mechanisms for health benefits of polyphenols is their ability to interact with biological systems through modulation of gene expression…
Conclusions and Future Perspectives
In this review, the impact of red wine polyphenols on human health was discussed and, more specifically, its impact on
- cardiovascular disease,
- cancer prevention and treatment,
- gut microbiota,
- oral health
- and diabetes.
From the reviewed animal and human studies, it can be concluded that there is a high potential in the polyphenols of wine, i.e., in its moderate consumption.
Among scientists, there is no consensus on whether these health benefits are due to ethanol or polyphenols’ presence in red wine. However, it can be concluded from all the above-mentioned studies that polyphenols are responsible to a greater extent for these properties.
Future studies should be more focused on investigating the impact of red wine polyphenols on the prevention and treatment of some other diseases.”
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