Multiple Myeloma an incurable disease, but I have spent the last 25 years in remission using a blend of conventional oncology and evidence-based nutrition, supplementation, and lifestyle therapies from peer-reviewed studies that your oncologist probably hasn't told you about.
Click the orange button to the right to learn more about what you can start doing today.
How best to restore myeloma gut health-diet or fecal transplant? I’m getting ahead of myself. The first issue is to establish the importance of a healthy gut for MM patients and survivors.
If you’ve been managing multiple myeloma, you’ve probably undergone chemotherapy. You may also have undergone antibiotics to reduce your risk of infection.
Because a healthy gut can help you manage infection in general or CAR-T therapy specifically, you want to know how best to enhance your gut health.
Back to my original question- how do you restore your gut health? According to the article linked below diet works better at restoring gut health.
Are you a MM patient? Have you undergone a lot of chemotherapy aka induction? Maybe an ASCT? Are you thinking about CAR-T cell therapy? I am a long-term MM survivor.
Email me at David.PeopleBeatingCancer@gmail.com to learn more about nutrition and supplementation that have been shown to enhance gut health.
Hang in there,
“A healthy diet is more effective than fecal transplants at restoring and protecting the gut microbiome.
Trillions of microbes live in your body. Far from being harmful, most of these microorganisms form a diverse and vital community that supports digestion, boosts the immune system, and helps protect against harmful pathogens.
When this microbial community is damaged or depleted, due to conditions like inflammatory bowel disease, antibiotic use, or bone marrow transplants, it becomes essential to restore it.
According to a new study published in Nature, the most effective way of rebuilding the microbiome is also the simplest: maintaining a healthy diet…”
A high-fat, low-fibre Western-style diet (WD) induces microbiome dysbiosis characterized by reduced taxonomic diversity and metabolic breadth1,2, which in turn increases risk for a wide array of metabolic3,4,5, immune6 and systemic pathologies.
Recent work has established that WD can impair microbiome resilience to acute perturbations such as antibiotic treatment7,8, although little is known about the mechanism of impairment and the specific consequences for the host of prolonged post-antibiotic dysbiosis.
Here we characterize the trajectory by which the gut microbiome recovers its taxonomic and functional profile after antibiotic treatment in mice on regular chow (RC) or WD, and find that only mice on RC undergo a rapid successional process of recovery.
Metabolic modelling indicates that a RC diet promotes the development of syntrophic cross-feeding interactions, whereas in mice on WD, a dominant taxon monopolizes readily available resources without releasing syntrophic byproducts.
Intervention experiments reveal that an appropriate dietary resource environment is both necessary and sufficient for rapid and robust microbiome recovery, whereas microbial transplant is neither.
Furthermore, prolonged post-antibiotic dysbiosis in mice on WD renders them susceptible to infection by the intestinal pathogen Salmonella enterica serovar Typhimurium.
Our data challenge widespread enthusiasm for faecal microbiota transplant (FMT) as a strategy to address dysbiosis, and demonstrate that specific dietary interventions are, at a minimum, an essential prerequisite for effective FMT, and may afford a safer, more natural and less invasive alternative.
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