a phase II study evaluating resveratrol (RES) in patients with Alzheimer disease showed that resveratrol can delay cognitive decline in the ability to perform daily tasks119
Can Resveratrol (RES) slow aging, mental decline, chronic disease and multiple myeloma diagnosis all at the same time? According to the studies linked and excerpted below, it can.
It’s a pretty easy leap, mentally speaking, from the idea of “eating nutritiously” to adding specific nutritional supplements to your diet that can reduce inflammation, reduce your risk of chronic diseases, to reducing your risk of dementia to even reducing your risk of cancer.
I’m not saying that any specific nutritional supplement is a magic bullet. Supplementing with RES daily won’t do you much good if you drink a bottle of booze and eat a dozen twinkies each and every day.
But I have been supplementing with Resveratrol for years. Since my multiple myeloma diagnosis in early 1994 I have made my health a priority. And I have remained in complete remission from my incurable cancer, multiple myeloma, since 1999. Coincidence?
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- MM Survivor
- MM Cancer Coach
- Director PeopleBeatingCancer
“The sirtuins (SIRT1–7) are a family of nicotinamide adenine dinucleotide (NAD+)-dependent deacylases with remarkable abilities to prevent diseases and even reverse aspects of ageing. Mice engineered to express additional copies of SIRT1 or SIRT6, or treated with sirtuin-activating compounds (STACs) such as RES and SRT2104 or with NAD+ precursors, have improved organ function, physical endurance, disease resistance and longevity. Trials in non-human primates and in humans have indicated that STACs may be safe and effective in treating inflammatory and metabolic disorders, among others…
Since the discovery almost 80 years ago that calorie restriction can extend the lifespan of rats2, great strides have been made in understanding why reducing calorie intake results in profound health benefits…
More recently, a phase II study evaluating RES in patients with Alzheimer disease showed that RES can delay cognitive decline in the ability to perform daily tasks119, a finding consistent with studies of resveratrol and SIRT1 in mouse models of Alzheimer disease120. A comprehensive summary and meta-analysis of clinical data has been recently published, the conclusion of which is that the human data are consistent with rodent studies, although more studies are warranted121.
Inflammation, Chronic Disease, Cognitive Function, Cancer-
Chronic systemic inflammation becomes increasingly associated with risk of death, loss of cognitive function and increasing dependency
Could five nutritional supplements be the proverbial “fountain of youth?” Could taking these five supplements be the ideal life extension therapy? I added each of the five supplements to my diet as I came upon anti-cancer research for this website and my own learning as a long-term survivor of an “incurable” cancer called multiple myeloma. I came to learn that reducing inflammation is critical in reducing my risk of a secondary cancer but also in reducing my risk of many chronic diseases including Alzheimer’s Disease.
These five supplements are part of my diet and I recommend that you supplement with them as well.
Is it coincidence that five of the most effective nutrition supplements to reduce your risk of cancers and other chronic diseases are the same five supplements that are also reduce inflammation in your body? Considering the study linked and excerpted below, is also coincidence that inflammation is the best predictor of successful aging?
I’ve lived through aggressive conventional/traditional chemotherapy and radiation only to “fail” and told I was terminal. I pursued a controversial alternative medicine and achieved cancer-free status in early ’99 where I remain to this day.
I supplement with the five nutritional, anti-oxidant supplements below. I have no idea how long I’ll live obviously but I will admit that I enjoyed finding and reading the study linked below.
Check back with me every decade or so and you can find out how I’m doing.
“According to ConsumerLabs.com optimal blood levels of vitamin D3 may prevent cancer, enhance bone health, reduce the risk of Parkinson’s, rheumatoid arthritis, heart attacks, diabetes, hypertension, reduce symptoms of fibromyalgia, reduce the risk uterine fibroids, Alzheimer’sdisease, dementia, depression, and other conditions.”
“Omega 3’s as nutritional supplementation may treat cancer, reduce the risk of heart attacks, reduce blood pressure, reduce homocystine levels, reduce the risk of blood clots, treat ulcerative colitis, rheumatoid arthritis, diabetes, depression, anxiety, stress, Alzheimers-like brain disease, age-related cognitive decline and other conditions.”
“Curcumin as nutritional supplement may help treat cancer, inflammation, ulcerative colitis, rheumatoid arthritis, osteo arthritis, diabetes, depression, anxiety, cognitive function and fatigue, chronic anterior uveitis and other conditions.”
“Resveritrol supplementation may treat cancer, may lower bad cholesterol, may reduce levels of inflammation, improves insulin sensitivity in diabetics, may help memory function and may help prevent the onset of Alzheimer’s Disease dementia and other neurodegenerative disorders.”
- regular green tea consumption is associated with 20% less risk of coronary artery disease as well as a reduced risk of death caused by heart disease–
- consumption of three or more cups of green tea daily reduces risk of ischemic stroke by 21%
- regular consumption of green tea reduced the risk of many cancers including prostate, breast and lung cancers-
- may decrease the risk of developing type 2 diabetes–
- laboratory research has suggested a role of green tea extracts in shrinking uterine fibroids–
- higher consumption of green tea has been associated with a lower prevalence of cognitive impairment in older adults-
- We identify potential drivers of multiple dimensions of the ageing process up to 110 years of age.
- Inflammation is the prime candidate amongst potential determinants of mortality, capability and cognition up to extreme old age.
- Telomere length does not predict successful ageing in the very and extreme old, but centenarians and their offspring maintain telomeres better than non-centenarians.
Centenarians are less susceptible to the diseases, functional losses and dependencies of old age than the general public. Why centenarians age differently, i.e. which biological and pathophysiological processes drive ageing at this extreme old age, is not known. We found that chronic systemic inflammation becomes increasingly associated with risk of death, loss of cognitive function and increasing dependency, but did not predict multimorbidity. In contrast, long telomeres might be important to become a centenarian but did not predict the ageing process further on. Suppression of chronic inflammation could be an essential step towards further improvements in human healthy lifespan.”