Silibinin Kills Lung Cancer Enhances Chemotherapy

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Integrative Therapies Cause Apoptosis in Lung Cancer and Can Enhance Toxic Chemotherapy

If you are reading this then you probably know that conventional oncology has little to offer lung cancer patients. Lung cancer is the deadliest of all cancers in the United States.  Depending on your stage at diagnosis, conventional oncology offers few curative therapies to lung cancer patients. Those chemotherapies that are cytotoxic to lung cancer “have limitations due to the associated acute and cumulative dose limiting toxicities and acquisition of drug resistance.”

While conventional oncology should be a component of your therapy it should be only one of several cancer therapies that will help you fight your aggressive, complicated cancer. There are dozens of studies that cite nutrition, supplementation (such as silibinin), lifestyle and other therapies that will work alongside whatever conventional therapies that your oncologist prescribes.

I am a long-term cancer survivor of an incurable cancer as well. I found it difficult to question my oncologist. He is a well-educated, experienced oncologist. It became clear to me, however, that conventional therapies such as radiation and chemotherapy weren’t going to help me beyond a year or two.

I have lived this long through evidence-based, cancer killing nutrition, supplementation, bone health, lifestyle and mind-body therapies.

The study linked and excerpted below cites silibinin (milk thistle) to be a nutraceutical that fights lung cancer. The brand of milk thistle that I take is Life Extension Foundation European Milk Thistle. I take this brand because it has been tested and approved by ConsumerLab.com, an independent evaluation service.

If you would like to learn more about non-conventional lung cancer therapies scroll down the page, post a question or a comment and I will reply to you ASAP.

Thank you

David Emerson

  • Cancer Survivor
  • Cancer Coach
  • Director PeopleBeatingCancer

Chemopreventive and anti-cancer efficacy of silibinin against growth and progression of lung cancer.

“The use of systemic chemotherapeutic drugs and molecular-targeted therapies in the treatment of patients with locally advanced or metastatic lung cancer has its limitations due to the associated acute and cumulative dose limiting toxicities and acquisition of drug resistance.

Prevention and therapeutic intervention by dietary agents including nutraceuticals which are non-toxic, cost-effective, and physiologically bioavailable, are emerging approaches in lung cancer management.

In this regard, silibinin, a natural flavonolignan, has been rigorously evaluated for the prevention and growth control of lung cancer through extensive in vitro and in vivo studies. Successful studies conducted so far, have established that silibinin is effective both alone and in combination with other agents (e.g., chemotherapeutic and epigenetic agents) in significantly inhibiting the growth of lung cancer cells.

In vivo, its effects have been shown to be mediated through inhibition of proliferation, angiogenesis and epigenetic-related events. Therefore, the present review focuses on encompassing the efficacy and mechanisms of silibinin against lung cancer.”


 Silibinin (INN), also known as silybin (both from Silybum, the generic name of the plant from which it is extracted), is the major active constituent of silymarin, a standardized extract of the milk thistle seeds, containing a mixture of flavonolignans consisting of silibinin, isosilibininsilicristinsilidianin and others.

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