The "best" human stem cells for your bone marrow transplant- PeopleBeatingCancer

The “best” human stem cells for your bone marrow transplant-

“his team reports that human stem cells (HSC) residing in the end (trabecular region) of the bones display the highest regenerative ability of the blood and immune system…”

I consider allogeneic stem cell transplants to be the most high risk, high reward procedure for blood cancers today. I had an autologous stem cell transplant for my multiple myeloma in 12/95. It put me into remission for less than a year. But other blood cancer patients can have a transplant and achieve a long-term remission or even be cured of their disease.

Let me be clear however. MM Patients undergoing an allogeneic stem cell transplant must use every therapy, conventional or non-conventional, that can increase their chance of a successful procedure.

The study linked and excerpted below is talking about allo (donor stem cells) not auto (your own stem cells). I have come to believe that not only is the local of human stem cells important but so is the conditioning of the stem cells. By conditioning I mean pre-habilitation. Nutrition, antioxidants, etc. before, during and after transplantation.

Your challenge is to choose the best hem./onc., working at the most experienced center (hospital), and choose the best procedure for the right risk/reward for you and your goals. All in a short period of time.

I am both a blood cancer survivor and cancer coach. Have you been diagnosed with a blood cancer? Are you considering a bone marrow transplant? What questions do you have? Please scroll down the page, post a question or comment and I will reply ASAP.

Thanks

David Emerson

Multiple Myeloma Survivor
MM Cancer Coach
Director PeopleBeatingCancer

Hematopoietic stem cell transplantation

“Hematopoietic stem cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood.^[1]^[2] It may be autologous (the patient’s own stem cells are used), allogeneic (the stem cells come from a donor) or syngeneic (from an identical twin)…”

Researchers Find Home of Best Stem Cells for Bone Marrow Transplants

“McMaster University researchers have revealed the location of human blood stem cells that may improve bone marrow transplants. The best stem cells are at the ends of the bone…It is hoped this discovery will lead to lowering the amount of bone marrow needed for a donation while increasing regeneration and lessening rejection in the recipient patients…

In a paper published online today by the journal Cell Stem Cell, his team reports that human stem cells (HSC) residing in the end (trabecular region) of the bones display the highest regenerative ability of the blood and immune system…”

Regional Localization within the Bone Marrow Influences the Functional Capacity of Human HSCs

“Our results reveal that direct characterization of indigenous human HSCs within the bone of humans uncovers unique interactions and location propensities that control HSC capacity in vivo…”