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Multiple Myeloma an incurable disease, but I have spent the last 25 years in remission using a blend of conventional oncology and evidence-based nutrition, supplementation, and lifestyle therapies from peer-reviewed studies that your oncologist probably hasn't told you about.

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Whole-Body Hyperthermia (sauna) vs. Multiple Myeloma

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“We aimed to clarify the therapeutic effects on Multiple Myeloma cells and their progenitors by hyperthermia. Heat treatment at 43°C time-dependently induced MM cell death.”

Whole-body hyperthermia (WBH) is too good to be true. It is the ultimate lifestyle therapy. At least it may be for multiple myeloma patients and survivors. I say this because research shows that

I am not saying that WBH will cure your multiple myeloma. I’m saying that cancer coaching since 2015 has taught me that neither conventional (traditional) therapies nor evidence-based non-conventional therapies alone will give you the combination of quality and quantity of life that you are searching for.

Most MM patients need induction therapy (RVd-D) in order to stabilize their incurable blood cancer. And it is those same myeloma patients who undergo 2,4,6 etc. cycles of induction therapy that need to enhance their immune function while weakening their monoclonal stem cells with whole-body hyperthermia.

The six blog posts that talk about WBH linked below explain the ins and outs of this non-conventional myeloma therapy.  Let me know what you think.

To Learn More About Your Prognosis for Multiple Myeloma click now

Thank you,

David Emerson

  • MM Survivor
  • MM Cancer Coach
  • Director PeopleBeatingCancer

Effective impairment of myeloma cells and their progenitors by hyperthermia

“Multiple myeloma (MM) remains incurable, and MM-initiating cells or MM progenitors are considered to contribute to disease relapse through their drug-resistant nature. In order to improve the therapeutic efficacy for MM, we recently developed novel superparamagnetic nanoparticles which selectively accumulate in MM tumors and extirpate them by heat generated with magnetic resonance.

We here aimed to clarify the therapeutic effects on MM cells and their progenitors by hyperthermia. Heat treatment at 43°C time-dependently induced MM cell death.

The treatment upregulated endoplasmic reticulum (ER) stress mediators, ATF4 and CHOP, while reducing the protein levels of Pim-2, IRF4, c-Myc and Mcl-1. Combination with the proteasome inhibitor bortezomib further enhanced ER stress to potentiate MM cell death. The Pim inhibitor SMI-16a also enhanced the reduction of the Pim-2-driven survival factors, IRF4 and c-Myc, in combination with the heat treatment. The heat treatment almost completely eradicated “side population” fractions in RPMI8226 and KMS-11 cells and suppressed their clonogenic capacity as determined by in vitro colony formation and tumorigenic capacity in SCID mice. These results collectively demonstrated that hyperthermia is able to impair clonogenic drug-resistant fractions of MM cells and enhance their susceptibility to chemotherapeutic drugs.

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3 comments
Evan & Terri says a couple of months ago

Thank you David. My husband will be on Daratemumab, Velcade, Revlimid and Dexamethasome. Good to know the sauna (we like traditional Finnish too) will help Velcade. Does anyone know if it can help the other meds? So much to know – it feels overwhelming but hoping to be as prepared as possible. Lots of toxins to sweat out for sure…

Reply
Evan & Terri says a couple of months ago

Would you recommend a traditional sauna to help with the toxic effects of induction therapy – is it better to wait a day after getting injected? I imagine it helps detox the chemicals. New to this site and trying to work out a plan to help my husband. Any thoughts or advice most welcome.

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    David Emerson says a couple of months ago

    Two answers- I myself use a Finnish aka traditional sauna because I like to sweat and found one study that cited heavy metals found in sweat. Sweat happens from other forms of sauna as well- I just sweat more in a traditional sauna.

    The other issue is the science of whole body hyperthermia- it is all about increasing the INTERNAL body temp of the person. All forms of sauna increase the internal body temp of the person.

    As for “waiting a day” I believe that different regimens stay in the person for different amounts of time. For example, I believe that vitamin C (oral dose) will stay in the body for about 24 hours. Velcade (bortizemib) stays in the body for days. Side note- sauna (increasing internal body temperature) enhances the efficacy of velcade.

    Thanks,
    David Emerson

    Reply
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