Magnesium Levels and Dementia

“In a study of more than 9,500 men and women, the highest or lowest levels of magnesium appeared to increase the chances for dementia by as much as 30 percent”

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It’s easy for researchers to say that blood levels of a mineral such as magnesium, too high or too low, cause dementia. While I think the study linked and excerpted below is an important finding, I think the study is only a first step. People need to close the loop if research indicates that we should keep an eye on our magnesium blood levels.

By “close the loop” I mean that an easy, cost-effective method for blood testing should be part of the discussion and a method for getting magnesium into our blood, again, easily and cheaply, must be advised.

I have my blood tested every year or so through LabCorp. The organization where I get many of my supplements, Life Extension Foundation, sells a bunch of different lab tests.

I take and recommend Life Extension Neuro-mag Magnesium L-threonate Dietary Supplements for several reasons. In addition to the benefits cited in the study below, this form of magnesium has been shown to help both my heart and brain function.

The Consumer lab.com evaluation of magnesium supplements that cites the benefits below requires membership log in

  • evaluated and approved by consumer lab.com for purity, absorbability-
  • plays an important role in brain cell functioning (minimizes my chemobrain…)
  • supports proper nervous system functioning
  • may prevent hearing loss from excessive noise
  • may decrease the risk of developing type 2 diabetes
  • may reduce the risk of stroke (I need this with chronic a-fib…)
  • may improve physical performance ( I need this with my nerve damage…)

I am both a cancer survivor and cancer coach. I take a variety of supplements but I don’t believe in “megadosing” of any single supplement. Please scroll down the page, post a question or comment and I will reply to you ASAP.

Thank you,

David Emerson

  • Cancer Survivor
  • Cancer Coach
  • Director PeopleBeatingCancer

High, Low Levels of Magnesium Linked to Dementia Risk

“In a study of more than 9,500 men and women, the highest or lowest levels of magnesium appeared to increase the chances for dementia by as much as 30 percent…

At this moment, magnesium levels are not routinely measured in daily clinical practice…”

“We already found that proton pump inhibitors [acid reflux drugs such as Nexium and Prilosec] are associated with a higher risk for abnormally low magnesium levels, but we continue looking into other drugs…”

 

Posted in chronic disease, dementia, diagnostic testing, Healthy Living Products, non-conventional therapies Tagged with:

Medicinal Marijuana – How can marijuana help with cancer or thyroid problems?

Medicinal Marijuana and its positive effects on modern medicine – How can marijuana help with cancer or thyroid problems?

Even though it has been a while since the views on marijuana in general have shifted and it has become far more acceptable to take part in the consumption of this substance, its use in medicine continues to be denied. However, for every person ready to stand against the claim that medicinal marijuana has a lot of beneficial uses, there is one who will defend these highly important benefits of using it.

Image result for image of Medicinal Marijuana

In order to fully understand the beneficial effects of marijuana on the suffering body, we must take a closer look at what it offers and interpret the situation for ourselves. With that being said, let’s start by looking at some important facts about marijuana, and how it is used in today’s medicine in various roles.

It’s a safe solution for many conditions

Despite being catalogues as a drug, it is also recognized as being a substance that is incredibly safe for consumption. As far as consumption for humans is concerned, marijuana is a very safe substance to ingest and compelling statistics show that there are virtually no risks that come with having this substance in your body. This is a great first step in showing that medicinal marijuana is a tool capable of doing good, not bad.

How it works

For those that don’t really understand how marijuana is supposed to help them from a medical perspective, it’s quite easy. Our bodies contain something called cannabinoids. These are also found in the cannabis plant, also known as marijuana. When the two, the body and the plant, come in contact, their individual sets of cannabinoids interact, thus creating a soothing reaction or a “feel good” reaction. This brings us to our next point of discussion, which is “how does marijuana help you exactly”.

There is a wide range of ailments that get easier to handle after consuming marijuana in one way or another.  Whether you’re battling cancer or are having trouble with thyroid health, it is believed that marijuana plays an important part in alleviating pain considerably and making sure that you get back on your feet as soon as possible. The main benefit of marijuana is the fact that it helps with the pain. Many medical conditions ale include a large amount of pain, and anything that might take the edge off is well appreciated. This brings us around to medicinal marijuana, which has that capability.

Those that are dealing with cancer most likely are familiar with the nausea which comes with the chemotherapy sessions. It is known that medicinal marijuana is an excellent nausea alleviator and can help with getting rid of that sensation. It’s just one of its many uses, another one being the fact that it can help regulate eating disorders by interacting with the body’s appetite. Surely you’ve heard of the famous “munchies” effect of smoking marijuana. That’s no placebo effect or weird coincidence, but a triggered effect which signals to professionals that there is a lot more to be exploited on that front with the help of marijuana.

 Taking care of pain

Nausea is not the only thing that can get treated. Raw pain is also a problem when you are under the effects of terrible diseases such as cancer. Being in constant pain and feeling powerless are things that those who suffer from cancer can easily recognize from experience. However, it has been proven on multiple occasions that medicinal marijuana has a huge impact on negating that pain and soothing the smoker. It is not commonly used among people of all ages battling cancer, in order to make the experience as painless as possible for them.

Hands-on impact of marijuana in today’s diseases and symptoms

Now that we’ve went through the theoretical part of marijuana, you might be interested in getting some information regarding the practical side. What exactly does marijuana do? Sure, it takes the pain away, but does it have any deeper impact on the body, so that it might become a very frequent solution among those suffering from cancer or other diseases?

Combating, managing and keeping diseases away

There is an array of known problems which benefit from the introduction of marijuana in your daily lifestyle choices. For example, glaucoma patients often time benefit from tremendously from marijuana.  The same goes for Alzheimer’s patients, epileptic seizure patients but also Hepatitis C patients. It has been scientifically proven that marijuana plays an important part in how these diseases can be cured or how they might become curable in the future, thanks to marijuana and the various studies created around it.

Losing weight is also on the menu

Weed might be associated with the munchies, but did you know that this plant also helps you lose weight and maintain a healthy caloric intake? It would seem that marijuana is directly responsible for modifications found before consumption, regarding the body’s insulin production. It would seem that the process is a lot speedier when marijuana is involved,. With that said, now you know that the fact that most marijuana smokers are very skinny is not a stereotype. It’s merely a fact, due to how their metabolism has been enhanced and it has grown.

It is a powerful tool against depression and anxiety

Depression and anxiety are conditions that can surface on their own, or triggered by something happening in the patient’s life, but also as side effects to many of the terrible diseases and conditions known to man. A person struck by cancer can’t be expected to keep up a smile all the time, and on the inside, they are probably not smiling at all. This can eventually lead to depression and a deep sense of hopelessness. The same thing goes for anxiety, as it is an often met side effect. With the help of marijuana, these problems can be taken care of before they get very serious. The plant plays the role of a mild sedative here, but it’s completely safe to use. The fact that it is something that puts the user in an overall good mood is also encouraging, as it means that people suffering from diseases can attempt to put away their sorrow for a moment and enjoy life.

Reverse gateway

One thing that authorities used to say about marijuana is that it is a gateway drug. While this is true, and many people find their way to more dangerous drugs with much dire consequences, it often starts with the consumption of marijuana. Today you find out that the reverse effect can take place as well.  This means that those who are addicted to much more powerful substances have a very good chance of getting clean by starting to consume marijuana. Similar to how you would stick an arm patch on your arm when you are ready to give up smoking, marijuana can be used in order to go back from more serious drugs to plain old pot.  Still, it would still be an addiction but one that could help people forget about the other, more powerful drugs out there.

Mental focus

Creativity can be quite scarce when your body is fighting a war inside your body. Resources are pretty limited as well. However, there is always marijuana. While some look down upon it, smoking marijuana actually improves your keen eye for details and creativity. Remaining creative in an environment where everything around you seems to hinder your creative juices can be quite difficult. Once again, pot seems to do a fantastic job here as it is able to provide the necessary spur of imagination which might get you through the whole ordeal of dealing with a terrible disease faster.

Fix what tobacco broke

Marijuana isn’t the only thing that people like to smoke. People also like smoking cigarettes.  Over time, many people turn in to medical emergency rooms with serious neck, through and lung complications. However, it’s never too late to get help, not even about charcoal black lungs. You see, marijuana also has the ability to reverse the negative impact that faulty lungs may have. According to testing sessions, it would seem that people with damaged lungs were able to come out of the experience with a far better set of airbags.  This is by no means a way of saying “smoke as much tobacco as you want because you can fix the problem with marijuana anyway). It’s rather an attempt to make readers see the true power of this plant and how it can be used for borderline miraculous recoveries, granted it is an indentified and approved string from a licensed medicinal vendor.

 Helpful with PTSD

PTSD or Post Traumatic Stress Disorder is something that occurs in situations where the one suffering from this condition has faced some kind of shock at some point during their life. As a result, even thought people move on mentally. There is something holding them back, almost impossible to describe scientifically.  That might be a bit of an exaggeration as professionals have been able to easily identify the “palpable” roots of PTSD situations. With that said, PTSD can be added to the list of things which can be treated by marijuana.

PTSD is one of the top reasoning behind so many people getting their own medicinal marijuana license. With the promise of a tremendously easier lifestyle as a result and the law on their side, many people have turned towards medicinal marijuana locations all across the country. Surely, when faced with the dilemma of “the current moment” in regards to these diseases and conditions, there’s no risk in trying, right?

Body and mind

Who would have thought that a regular visit to thyroid pharmacist would have actually sent you to kushly. There is still much to be learned about marijuana in general, and with the current laws proving that they can be more flexible towards the subject, the future remains very bright and promising. This is the case not just for those already suffering from a condition but also for those that simply want to combat the effects of a terrible disease before they even hint at a possible problem.

Marijuana and mental health

Of course, everyone knows the unjust stigma hovering around marijuana, and the “hallow-mind” effect it promotes in its users. As a direct result, many are very concerned about the mental health effects consuming marijuana might have and how patients are supposed to deal with the situation. The truth of the matter however is that marijuana does not pose an imminent threat, or a threat at all for that matter. Those who consume marijuana frequently claim that there have been no signs of their minds being less efficient than they were previously.

There is also a different aspect of this issue that needs to be bought to your attention, and that is the fact that anxiety can be a direct effect of marijuana consumption. However, before you get too worried, know that this is only the case when THC, the substance within marijuana, is consumed in extremely high doses.  If you are close to going over that limit in terms of consumed quantities, it’s a clear sign that you need to ease up and be more tempered with your resources.

The studies regarding marijuana consumption and mental health continue, as more studies claim that marijuana is dangerous for one’s mind while another claims that it incredibly benefic.  One thing is for sure however, and that is the fact that marijuana will continue to play an important role in the evolution of medicinal solutions. As people will continue to be in pain as a result of cancer, or will experience nausea after their chemo sessions, marijuana will still be on the table as a valid and potent answer. The only thing that remains to be seen is just how much emphasis will be put on this substance from both patient and medical expertise points of view.

Posted in integrative therapy, non-conventional therapies, side effects ID and prevention Tagged with:

Cannabinoids- Psoriasis, Severe Itching, Dermatitis and Melanoma

“Cannabinoids – a class of chemicals found in cannabis – may be effective as a topical treatment for an array of skin diseases, including psoriasis, severe itching, and atopic and contact dermatitis.

Research continually reveals evidence-based, non-conventional therapies that are less expensive, cause few is any side effects and can be more effective than conventional (FDA approved) therapies. I am not saying that conventional medicine does not have it’s place in our medicine cabinet. I am saying that if you or a loved one has some sort of medical problem you will do well to research the spectrum of both conventional and non-conventional therapies.

Image result for image of cannabis salve

The two articles linked and excerpted below are examples of what I am talking about. Some sort of cannabis salve/cream/ointment may be able to address your skin issue more effectively than a prescription therapy.

And don’t get me started on melanoma therapies. If you have been diagnosed with this aggressive form of skin cancer, depending on your stage, your therapy options may be limited. And those conventional melanoma chemotherapies that may slow your cancer can include a host of toxic short, long-term and late stage side effects.

I am a cancer survivor and cancer coach. I have learned through experience and research that if you have an aggressive cancer like melanoma your long-term solution may be to integrative both conventional and non-convenventional therapies.

Please scroll down the page, post a question or comment and I will reply to you ASAP.

Thank you,

David Emerson

  • Cancer Survivor
  • Cancer Coach
  • Director PeopleBeatingCancer

The role of cannabinoids in dermatology

“In recent years, researchers have also investigated its use for the treatment of dermatologic conditions including pruritus, inflammatory skin disease, and skin cancer…

Cannabinoids may also have anti-inflammatory properties useful for the treatment of both allergic contact dermatitis and atopic dermatitis…

Limited studies on its uses for other skin conditions also exist. Cannabinoids may be useful for psoriasis, as THC, cannabidiol, cannabinol, and cannabigerol have been found to inhibit keratinocyte proliferation in hyperproliferating human keratinocyte cell lines...”

Topical cannabinoids may help to treat skin diseases

“Cannabinoids – a class of chemicals found in cannabis – may be effective as a topical treatment for an array of skin diseases, including psoriasis, severe itching, and atopic and contact dermatitis. This is the conclusion of a new review by researchers from the University of Colorado…

The team also noted a link between injection with tetrahydrocannabinol (THC) – the psychoactive compound in cannabis – and a reduction in tumor growth in mice with melanoma, the deadliest form of skin cancer…

In the United States, cannabis is becoming increasingly legalized for medicinal purposes, including for the treatment of nausea, pain, and inflammation

A number of studies have also investigated whether the active components of cannabis – known as cannabinoids – might show promise as a treatment for skin disorders…”

 

 

Posted in chronic disease, integrative therapy, non-conventional therapies Tagged with:

Antiangiogenic Inhibition of Angiosarcomas both Conventionally and Non-Conventionally

studies have demonstrated that inhibition of angiogenic pathways or disruption of established vasculature can attenuate the growth of sarcomas

Angio sarcomas are a rare and not-well studied cancer. As such therapies for the angio sarcoma patient are now well understood. The study linked and excerpted below cites conventional antiangiogenic chemotherapy to augment the standard chemotherapy regimens to fight angio sarcomas.

Liver Angiosarcoma Pictures

I am both a cancer survivor and cancer coach who lives in complete remission from his “incurable” cancer primarily through evidence-based, non-toxic antiagiogenic foods and supplementation.

Have you been diagnosed with a type of angiosarcoma? Please scroll down the page, post a question or comment and I will reply to you ASAP.

Thank you,

David Emerson

  • Cancer Survivor
  • Cancer Coach
  • Director PeopleBeatingCancer

Targeted antiangiogenic agents in combination with cytotoxic chemotherapy in preclinical and clinical studies in sarcoma

“In recent years, studies have demonstrated that inhibition of angiogenic pathways or disruption of established vasculature can attenuate the growth of sarcomas. However, when used as monotherapy in the clinical setting, these targeted antiangiogenic agents have only provided modest survival benefits in some sarcoma subtypes, and have not been efficacious in others. Preclinical and early clinical data suggest that the addition of conventional chemotherapy to antiangiogenic agents may lead to more effective therapies for patients with these tumors..”

Angiosarcoma

Angiosarcoma is a cancer of the cells that line the walls of blood vessels or lymphatic vessels. The lining of the vessel walls is called the endothelium. Cancers from the walls of blood vessels are called hemangiosarcomas, and cancers from the walls of lymphatic vessels are called lymphangiosarcomas…”

Angiosarcoma Prognosis

“Angiosarcoma patients are mostly diagnosed after the tumor has spread all over the body and this type of late identification may result in a poor prognosis. According to various studies, improved prognosis is achieved when patients have smaller tumors that can be easily removed from the body…”

What is Angiosarcoma?

“Sarcomas are soft tissue tumors that can develop in any part of the body. The term “sarcoma” has a Greek origin, which means “fleshy growth.” This category of tumors consists of more than 70 subtypes, which are classified on the basis of two factors—the tissue of origin and chromosomal abnormalities. Each of these has its own unique features…”

Posted in integrative therapy, non-conventional therapies Tagged with:

Evidence-based, Non-Toxic Therapies for Major Depressive Disorder

the large number of questions that were submitted suggest that there are many, many depressed patients who would benefit from having better-tolerated therapies, yet remarkably few controlled studies of potential remedies.”

I am not a psychiatrist or any sort of medical professional. I readily admit that depression is a complicate issue that I know little about. I am a long-term cancer survivor and cancer coach. I am blogging about the article linked and excerpted below because of my own experiences and research into a common occurrence in cancer care called “over-treatment.”

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I read the article below through the eyes of a cancer survivor who lives with long-term and late stage collateral damage brought on by several years of aggressive conventional oncologist therapies. Therapies that resulted in two remissions, two relapses and my oncologist remarking “there is nothing more we can do for you.”

My question is, is it me or is the author of the article below talking about experimenting on his patients hoping for a  response rate of 40%-60%?

The author refers to this “response rate” and then questions the many short, long-term and late stage side effects that aren’t known or researched.

Balance the experimentation and collateral damage (side effects) of toxic therapies for depression with studies that cite the same success rate with non-toxic depression therapies such as curcumin, omega-3 fatty acids and/or moderate exercise such as yoga and it seems clear to me that evidence-based, non-toxic depression therapies should be the first line of treatment for major depressive disorder.

Please scroll down the page, post a question or comment and I will reply to you ASAP.

Thank you,

David Emerson

  • Cancer Survivor
  • Cancer Coach
  • Director PeopleBeatingCancer 

Efficacy and safety of curcumin in major depressive disorder: a randomized controlled trial.

“This study provides first clinical evidence that curcumin may be used as an effective and safe modality for treatment in patients with MDD without concurrent suicidal ideation or other psychotic disorders.”

Omega-3 fatty acids in major depressive disorder A preliminary double-blind, placebo-controlled trial

“From the preliminary findings in this study, omega-3 PUFAs could improve the short-term course of illness and were well tolerated in patients with major depressive disorder…”

Solving Clinical Challenges in Major Depression

“Of course, the relevant change in DSM-5 reflects the fact that it is neither justified nor helpful to try to differentiate grief from depression when the individual presents with a full depressive syndrome (a recurrent episode of MDD in this case). Specifically, studies have shown that depressive episodes of bereaved individuals are very similar to those experiencing other kinds of stressful life events…

With respect to pharmacotherapy of depressive disorders, there were several questions about differentiating the role(s) of the more recently introduced antidepressants from the generically available first-line therapies, as well as questions reflecting abiding concerns about the widespread use of second generation antipsychotics (SGAs) relatively early in treatment algorithms. I think it is fair to say that vilazodone and vortioxetine are not simply “me too” drugs and both offer some potentially unique properties compared with FDA-approved SSRIs

No session on MDD is complete without a number of cases and a slew of questions about treatment-resistant depression. There is little uncertainty about the efficacy of SGAs when used as adjuncts to otherwise ineffective antidepressants: multiple positive placebo-controlled studies have established the efficacy of risperidone, aripiprazole, olanzapine, quetiapine, and brexpiprazole for this indication. However, real questions persist about cost-effectiveness and the best practices to mitigate risks of weight gain and other adverse metabolic effects and to help ensure patient safety during longer-term use of SGAs...

The results of a recently published study that compared therapies for veterans with treatment-resistant depression are generally consistent with this approach: adjunctive aripiprazole was only nominally more effective than adjunctive bupropion

Vigilant monitoring of weight during SGA therapy and assertive intervention when patients continue to gain weight despite sound clinical management are essential strategies to keep the benefit to risk ratio on the favorable side...

As reported by a Task Force of the American psychiatric Association,7 there is ample evidence that an infusion of a sub-anesthetic dose of ketamine (typically 0.4-0.5 mg/kg infused over 40 minutes) can have rapid and dramatic effects for people who have not responded to multiple trials of standard antidepressants. Antidepressant effects generally persist for 4 to 7 days after a single infusion and typically are not linked to psychotomimetic or dissociative adverse effects. Response rates typically range from 40% to 60% after one week of therapy and preliminary results suggest that the benefits may be sustained by once or twice weekly infusions on an ongoing basis

Nevertheless, there are many important questions to be answered about longer-term efficacy and safety of such extended courses of intravenous ketamine therapy.9,10 That said, the remarkably rapid efficacy of a treatment that does not directly target monoaminergic neurotransmission has had a revitalizing effect on drug development and it is possible that other medications with less “baggage” than ketamine will be identified that exert antidepressant effects via modulation of glutamatergic neurotransmission…

With respect to managing the adverse effects of our more and less commonly used treatments for depression, the large number of questions that were submitted suggest that there are many, many depressed patients who would benefit from having better-tolerated therapies, yet remarkably few controlled studies of potential remedies. Beyond weight gain, which is more strongly associated with use of adjunctive SGAs than antidepressant monotherapy, treatment-emergent sexual dysfunction is an endemic problem with the SSRIs and SNRIs…

 

 

 

 

 

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Posted in chronic disease, Healthy Living Products, non-conventional therapies, side effects ID and prevention Tagged with:

High Risk for Depression- Should you Take Antidepressants as a Preventative?

…although antidepressants are usually well tolerated, these medications can come with side effects ranging from headaches to diarrhea to life-threatening reactions.”

Remember that all medications have side-effects. Some side-effects may be relatively minor or take years to show themselves. But all medications change the body’s chemistry. That’s how they work.

The article linked and excerpted below asks if people at high risk for depression- cancer survivors, stoke patients and others, should take antidepressants prophylactically in an effort to not become depressed.

I am both a cancer survivor and cancer coach. The idea of taking antidepressants prophylactically is copying an idea that is entrenched in the world of cancer. Over-treatment is a common practice for early stage cancers such as breast, prostate and thyroid cancers.

A more effective, less expensive therapy for head and neck cancer survivors, as an example, would be for survivors to undergo an evidence-based, non-toxic, non-conventional therapy. Studies have cited curcumin as being cytotoxic to head and neck cancer. At the same time, curcumin has been shown to reduce depression.

Rather than take a toxic, side-effect causing drug, it may be more effective, more prophylactic and reduce the patient’s risk of relapse simply by taking curcumin.

I have lived in complete remission from my “incurable” cancer since 1999. I have supplemented with curcumin, among other evidence-based, anti-cancer therapies, for years. I supplement with Life Extension Super Bio-Curcumin for this formula’s enhanced bioavailability.

I find that in health often the simple therapies are the most effective.

Thanks,

David Emerson

  • Cancer Survivor
  • Cancer Coach
  • Director PeopleBeatingCancer

Should people without depression take medication to prevent it?

“For years, physicians have prescribed antidepressants to treat people grappling with depression. Some people can benefit from taking these medications during an acute episode. Others with a history of recurrent depression may take antidepressants to help prevent relapses

But researchers are studying a new use for these medications: to prevent depression in people who may have never had it before.

It has long been known that people with head and neck cancer are vulnerable to becoming depressed. These types of cancers can impair functionality at the most basic levels, like speaking or swallowing. Treatments, such as surgery and radiation, for these diseases can be debilitating. Some studies have estimated that up to half of patients with head and neck cancers may experience depression…

A group of researchers in Nebraska examined what would happen if non-depressed patients were given antidepressants before receiving treatment for head and neck cancer. Published in 2013, the results of the randomized, placebo-controlled trial were startling: Patients taking an antidepressant were 60 percent less likely to experience depression compared with peers who were given a placebo…

A meta-analysis published in 2014 found that prophylactic antidepressants cut down the incidence of depressive episodes among people receiving therapy for hepatitis C by more than 40 percent. Randomized trials suggest that patients who take antidepressants early after a stroke experience significantly lower rates of depression. Small studies have also found that people receiving treatment for melanoma may be less likely to develop depressive symptoms if they are pre-treated with antidepressants…

And although antidepressants are usually well tolerated, these medications can come with side effects ranging from headaches to diarrhea to life-threatening reactions…

 

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Posted in chronic disease, non-conventional therapies Tagged with:

Evidence-based Non-Toxic Therapies for Extramedullary Multiple Myeloma

“Most multiple myeloma patients that present with extramedullary disease will need aggressive treatment.”

According to the article linked and excerpted below,”extramedullary multiple myeloma is the clonal plasma cell spread to tissues outside of bone marrow.” To put this in layman’s terms, when MM spreads outside of the bone it forms extramedullary tumors.

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A MM specialist is quoted in the article below by saying that extramedullary disease can happen after a person relapses 7 or 8 times. If a MMer has relapsed repeatedly wouldn’t they want to try an integrative or non-toxic approach to their MM therapy?

I am both a long-term MM survivor and MM cancer coach. I have lived in complete remission from my MM since 1999. I live an evidence-based, non-toxic, anti-MM lifestyle through nutrition, supplementation, bone health and other therapies.

If you have extramedullary MM and you would like to learn more about evidence-based, non-toxic MM therapies please register for the free webinar linked on the right hand side of the page.

Please scroll down the page, post a question or comment if you would like to ask me a question.

Thank you,

David Emerson

  • MM Survivor
  • MM Cancer Coach
  • Director PeopleBeatingCancer

Paths Forward for Confronting Extramedullary Multiple Myeloma

“Extramedullary dissemination of multiple myeloma portends more aggressive disease but no predictive circulating biomarkers for this condition are yet available and the molecular mechanisms involved in extramedullary progression are still being learned…

“Extramedullary MM is the clonal plasma cell spread to tissues outside of bone marrow; it is present at the time of diagnosis in 7% to 20% of patients and occurs with disease progression and relapse...

Is not uncommon for patients to have other features of advancing myeloma including renal failure or hypercalcemia,” Dr Fonseca explained. “Most patients that present with extramedullary disease will need aggressive treatment.”

Physicians need to be aware that these can be confused with other tumors, Dr Fonseca said. “These clinical presentations are atypical for what we normally think about MM.”

If the disease is able to grow outside the regular niche (the bone marrow), that is a sign that the tumor cells have a more aggressive biology and the disease is more resistant to conventional therapy,” he explained. “Therapy may result in a response, but on average, the disease is more likely to relapse again. Systemic therapy is used to treat a patient with bone marrow involvement and additional extramedullary disease.”

 

 

Posted in Multiple Myeloma Tagged with:

Evidence-based, Non-toxic Arthritis Therapy

“Treatment with omega-3 fatty acids has been associated with improvement in some outcome measures in rheumatoid arthritis…they do provide a compelling justification for curcumin’s use as a dietary adjunct to conventional therapy”

It may sound odd for a cancer survivor and cancer coach to be writing about arthritis (art). Art and cancer have two important things in common.

Image result for image of arthritis in knee

  1. Both of these diseases are caused by inflammation and
  2. both of these diseases are managed by curcumin and omega 3 fatty acids

I hope you noticed that I used the word managed and not cured. Too many articles on the Internet talk about curing this disease and that disease. While omega 3’s and curcumin may eliminate your art completely I find it more reasonable to talk about the studies below that cite fish oil and curcumin to work synergistically with conventional therapies. This integrative approach to therapy is the future of cancer therapy as well.

I have supplemented with Life Extension Super Omega 3 for years now. In addition I have been taking Life Extension Super BioCurcumin for years as well. Both formulas have been evaluated and approved by ConsumerLab.com, an independent testing service. I take these supplements because studies confirm their benefit to both my brain and heart function.

If you would like to learn more about anti-inflammatory nutrition and supplementation please scroll down the page, post a question or comment and I will reply to you ASAP.

Thank you,

David Emerson

  • Cancer Survivor
  • Cancer Coach
  • Director PeopleBeatingCancer

Omega-3 fatty acids in rheumatoid arthritis: an overview.

“To review background, pharmacological properties, mechanisms of action, and published clinical experience using omega-3 fatty acids in rheumatoid arthritis…

Omega-3 fatty acids are superior with respect to placebo in improving some outcome measures, and decrease the long-term requirements for nonsteroidal antiinflammatory drugs…

Treatment with omega-3 fatty acids has been associated with improvement in some outcome measures in rheumatoid arthritis….”

Efficacy of Turmeric Extracts and Curcumin for Alleviating the Symptoms of Joint Arthritis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials

“We systemically evaluated all RCTs of turmeric extracts and curcumin for treating arthritis symptoms to elucidate the efficacy of curcuma for alleviating the symptoms of arthritis. Literature searches were conducted using 12 electronic databases, including PubMed, Embase, Cochrane Library, Korean databases, Chinese medical databases, and Indian scientific database…

In conclusion, although the studies used in this meta-analysis do not have sufficient number of subjects to permit a definitive recommendation for the use of curcumin as a treatment for arthritis, they do provide a compelling justification for its use as a dietary adjunct to conventional therapy. Furthermore, they also provide sufficient evidence to support larger clinical trials that could eventually lead to its acceptance as a standard therapy for many forms of arthritis and possibly other inflammatory conditions.”

 

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Posted in chronic disease, Healthy Living Products, integrative therapy

Evidence-Based, Non-Toxic Protection from Chemo-Induced Bladder Damage

“These results suggest that taurine offers a protective effect against CP-induced urinary bladder damage… Moringa leaves play an important role in ameliorating and protecting the bladder from CP toxicity”

The bad news is that if you undergo a chemotherapy regimen called cytoxan aka cyclophosphomide, you will probably end up with bladder damage. The damage may be more or less serious but your bladder will take a serious dose of toxicity. There is even an annual increase in developing a “treatment-related secondary cancer” in the form of bladder cancer.

Mild Interstitial Cystitis

The good news is that you can prevent damage to your bladder from cytoxan toxicity by supplementing with either/or taurine or Moringa oleifera. The studies linked and excerpted below say that you should supplement both before cytoxan as well as after. If you are reading this before you undergo cytoxan chemotherapy then you are all set.

If you are reading this blog post after you have already undergone cytoxan chemotherapy then you are in the position that I am. I developed bladder damage several years after cytoxan/cyclophosphomide therapy. I underwent cytoxan in September of 1995 and I am supplementing to reduce my risk of bladder cancer.

I am both a cancer survivor and cancer coach. Have you been diagnosed with cancer? If you would like to learn more about evidence-based integrative therapies to both enhance chemotherapy while reducing toxicity please scroll down the page, post a question or comment and I will reply to you ASAP.

Thank you,

David Emerson

  • Cancer Survivor
  • Cancer Coach
  • Director PeopleBeatingCancer

Protective effect of taurine against cyclophosphamide-induced urinary bladder toxicity in rats.

“Conversely, pretreatment with taurine (1% in drinking water to reach a dose of 1 g/kg per day) for 7 days before and 1 day after CP injection produced a significant decrease in urinary bladder weight (oedema) and a marked decrease in vascular congestion and haemorrhage, as well as a profound improvement in histological structure. Moreover, taurine pretreatment resulted in a significant decrease in lipid peroxide in urinary bladder tissue and glutathione content was greatly restored…

These results suggest that taurine offers a protective effect against CP-induced urinary bladder toxicity and may, therefore, decrease the limitation on its clinical application…”

The protective effect of Moringa oleifera leaves against cyclophosphamide-induced urinary bladder toxicity in rats.

“Cyclophosphamide (CP), an alkylating antineoplastic agent is widely used in the treatment of solid tumors and B-cell malignant disease. It is known to cause urinary bladder damage due to inducing oxidative stress…

From the results obtained in this work, we can say that Moringa leaves play an important role in ameliorating and protecting the bladder from CP toxicity…”

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Posted in chronic disease, Healthy Living Products, non-conventional therapies, side effects ID and prevention Tagged with:

Melanoma Therapy- Kills or Inhibits Melanoma Growth by 69% “Without Harming Healthy Cells”

In the study, the compound caused human melanoma cells to die and inhibited tumor growth by about 69 percent in a mouse model…

Normally, I never blog about therapies that “show promise” are “hopeful” or are anything other than results based on research. I am breaking my rule because of the cancer, melanoma, (mel) that is the cancer being studied. Not only is mel an incredibly aggressive disease but it has taken two of my best friends in their twenties. Melanoma is personal.

 

Equally as important, when a cancer therapy kills a cancer cells “without harming nearby healthy cells” I admit that I take notice. I live with long-term and late stage side effects from the conventional therapies that I underwent when I was first diagnosed. As the saying goes, “the cure is worse than the disease.”

Have you been diagnosed with melanoma? As a cancer survivor and cancer coach I can research clinical trials testing NISC-6. Scroll down the page, post a question or comment and I will reply to you ASAP.

In the meantime please consider supplementing with cruciferous vegetables. I take a Standard Process – Cruciferous Complete because if the anti-cancer action of naturally occurring isothiocyanates.

Thank you,

David Emerson

  • Cancer Survivor
  • Cancer Coach
  • Director PeopleBeatingCancer

Compound shows promise in treating melanoma

“While past attempts to treat melanoma failed to meet expectations, an international team of researchers are hopeful that a compound they tested on both mice and on human cells in a petri dish takes a positive step toward creating a drug that can kill melanoma cancer cells without harming nearby healthy cells

In the study, the compound caused human melanoma cells to die and inhibited tumor growth by about 69 percent in a mouse model

The isoselenocynate moiety was designed based on naturally occurring isothiocyanates, which can be found in vegetables, such as broccoli and cauliflower, and are known for their cancer prevention properties…

“There are a lot of recommendations that, for example, broccoli can reduce your chances of getting cancer,” said Sharma. “Those are OK recommendations for prevention, but the compounds in the vegetables alone may not be potent enough to be used in a therapeutic environment.”

To improve the effectiveness, the researchers modified the drug by replacing the sulfur in a compound they studied earlier with selenium, as well as varying the length of the alkyl chain to create isoselenocynate. Several variations were screened before the researchers arrived at a compound that they thought could kill the cancer cells without increasing toxicity levels…

Sharma said NISC-6 may also work on other forms of cancer, which will likely be included in future research…”

Design, synthesis, and identification of a novel napthalamide-isoselenocyanate compound NISC-6 as a dual Topoisomerase-IIα and Akt pathway inhibitor, and evaluation of its anti-melanoma activity.

“Furthermore, NISC-6 effectively induced apoptosis in human melanoma cells, inhibited tumor growth by ∼69% in a melanoma mouse xenograft model, and showed excellent compliance with the Lipinski’ rule of five, suggesting both its efficacy and drug-like behavior under physiological conditions…”

Posted in Healthy Living Products, side effects ID and prevention Tagged with:

You Can Take Control of Your Multiple Myeloma

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